| The mechanism of insulin resistance caused by HIV protease inhibitor therapy H Murata, PW Hruz, M Mueckler Journal of Biological Chemistry 275 (27), 20251-20254, 2000 | 727 | 2000 |
| Investigating the cellular targets of HIV protease inhibitors: implications for metabolic disorders and improvements in drug therapy H Murata, PW Hruz, M Mueckler Current Drug Targets-Infectious Disorders 2 (1), 1-8, 2002 | 586 | 2002 |
| Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations H Murata, PW Hruz, M Mueckler Aids 16 (6), 859-863, 2002 | 320 | 2002 |
| Trehalose inhibits solute carrier 2A (SLC2A) proteins to induce autophagy and prevent hepatic steatosis. BJ DeBosch, MR Heitmeier, AL Mayer, CB Higgins, JR Crowley, TE Kraft, ... Science Signaling 9 (416), 1-13, 2016 | 264 | 2016 |
| Disruption of hepatic adipogenesis is associated with impaired liver regeneration in mice E Shteyer, Y Liao, LJ Muglia, PW Hruz, DA Rudnick Hepatology 40 (6), 1322-1332, 2004 | 263 | 2004 |
| Structural analysis of the GLUT1 facilitative glucose transporter MMM Paul W. Hruz Molecular membrane biology 18 (3), 183-193, 2001 | 225 | 2001 |
| HIV protease inhibitors acutely impair glucose-stimulated insulin release JC Koster, MS Remedi, H Qiu, CG Nichols, PW Hruz Diabetes 52 (7), 1695-1700, 2003 | 169 | 2003 |
| The role of protease inhibitors in the pathogenesis of HIV-associated lipodystrophy: cellular mechanisms and clinical implications OP Flint, MA Noor, PW Hruz, PB Hylemon, K Yarasheski, DP Kotler, ... Toxicologic pathology 37 (1), 65-77, 2009 | 141 | 2009 |
| Genetic disruption of myostatin reduces the development of proatherogenic dyslipidemia and atherogenic lesions in Ldlr null mice P Tu, S Bhasin, PW Hruz, KL Herbst, LW Castellani, N Hua, JA Hamilton, ... Diabetes 58 (8), 1739-1748, 2009 | 133 | 2009 |
| Delayed hepatocellular mitotic progression and impaired liver regeneration in early growth response-1-deficient mice Y Liao, ON Shikapwashya, E Shteyer, BK Dieckgraefe, PW Hruz, ... Journal of Biological Chemistry 279 (41), 43107-43116, 2004 | 129 | 2004 |
| Indinavir induces acute and reversible peripheral insulin resistance in rats PW Hruz, H Murata, H Qiu, M Mueckler Diabetes 51 (4), 937-942, 2002 | 124 | 2002 |
| A structural basis for the acute effects of HIV protease inhibitors on GLUT4 intrinsic activity J Hertel, H Struthers, CB Horj, PW Hruz Journal of Biological Chemistry 279 (53), 55147-55152, 2004 | 121 | 2004 |
| GLUT4, GLUT1, and GLUT8 are the dominant GLUT transcripts expressed in the murine left ventricle L Aerni-Flessner, M Abi-Jaoude, A Koenig, M Payne, PW Hruz Cardiovascular diabetology 11, 1-10, 2012 | 110 | 2012 |
| HIV protease inhibitors act as competitive inhibitors of the cytoplasmic glucose binding site of GLUTs with differing affinities for GLUT1 and GLUT4 RC Hresko, PW Hruz PloS one 6 (9), e25237, 2011 | 105 | 2011 |
| SLC2A8 (GLUT8) is a mammalian trehalose transporter required for trehalose-induced autophagy AL Mayer, CB Higgins, MR Heitmeier, TE Kraft, X Qian, JR Crowley, ... Scientific reports 6 (1), 38586, 2016 | 103 | 2016 |
| Liver regeneration is impaired in lipodystrophic fatty liver dystrophy mice V Gazit, A Weymann, E Hartman, BN Finck, PW Hruz, A Tzekov, ... Hepatology 52 (6), 2109-2117, 2010 | 95 | 2010 |
| Cysteine-scanning mutagenesis of transmembrane segment 7 of the GLUT1 glucose transporter PW Hruz, MM Mueckler Journal of Biological Chemistry 274 (51), 36176-36180, 1999 | 87 | 1999 |
| 3-Hydroxy-3-methylglutaryl coenzyme A lyase (HL). Cloning of human and chicken liver HL cDNAs and characterization of a mutation causing human HL deficiency. GA Mitchell, MF Robert, PW Hruz, S Wang, G Fontaine, CE Behnke, ... Journal of Biological Chemistry 268 (6), 4376-4381, 1993 | 85 | 1993 |
| Effects of the HIV protease inhibitor ritonavir on GLUT4 knock-out mice AK Vyas, JC Koster, A Tzekov, PW Hruz Journal of Biological Chemistry 285 (47), 36395-36400, 2010 | 83 | 2010 |
| Direct comparison of the acute in vivo effects of HIV protease inhibitors on peripheral glucose disposal Q Yan, PW Hruz JAIDS Journal of Acquired Immune Deficiency Syndromes 40 (4), 398-403, 2005 | 82 | 2005 |
Brian DeBoschAssistant Professor of Pediatrics and Cell Biology and PhysiologyVerified email at kids.wustl.edu
