Differentiation of cardiomyocytes and generation of human engineered heart tissue K Breckwoldt, D Letuffe-Brenière, I Mannhardt, T Schulze, B Ulmer, ... Nature protocols 12 (6), 1177-1197, 2017 | 263 | 2017 |
CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for … D Mosqueira, I Mannhardt, JR Bhagwan, K Lis-Slimak, P Katili, E Scott, ... European heart journal 39 (43), 3879-3892, 2018 | 213 | 2018 |
Human iPSC-derived cardiomyocytes cultured in 3D engineered heart tissue show physiological upstroke velocity and sodium current density MD Lemoine, I Mannhardt, K Breckwoldt, M Prondzynski, F Flenner, ... Scientific reports 7 (1), 5464, 2017 | 199 | 2017 |
Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy M Prondzynski, MD Lemoine, ATL Zech, A Horváth, V Di Mauro, ... EMBO Molecular Medicine 11 (12), e11115, 2019 | 104 | 2019 |
Evaluation of MYBPC3 trans-splicing and gene replacement as therapeutic options in human iPSC-derived cardiomyocytes M Prondzynski, E Krämer, SD Laufer, A Shibamiya, O Pless, F Flenner, ... Molecular Therapy-Nucleic Acids 7, 475-486, 2017 | 94 | 2017 |
Human induced pluripotent stem cell–derived engineered heart tissue as a sensitive test system for QT prolongation and arrhythmic triggers MD Lemoine, T Krause, JT Koivumäki, M Prondzynski, ML Schulze, ... Circulation: Arrhythmia and Electrophysiology 11 (7), e006035, 2018 | 89 | 2018 |
Gene therapy strategies in the treatment of hypertrophic cardiomyopathy M Prondzynski, G Mearini, L Carrier Pflügers Archiv-European Journal of Physiology 471, 807-815, 2019 | 69 | 2019 |
Blinded contractility analysis in hiPSC-cardiomyocytes in engineered heart tissue format: comparison with human atrial trabeculae I Mannhardt, A Eder, B Dumotier, M Prondzynski, E Krämer, M Traebert, ... Toxicological sciences 158 (1), 164-175, 2017 | 69 | 2017 |
Activation of Autophagy Ameliorates Cardiomyopathy in Mybpc3-Targeted Knockin Mice SR Singh, ATL Zech, B Geertz, S Reischmann-Düsener, H Osinska, ... Circulation: Heart Failure 10 (10), e004140, 2017 | 57 | 2017 |
Functional role of the interaction between polysialic acid and myristoylated alanine-rich C kinase substrate at the plasma membrane T Theis, B Mishra, M Von Der Ohe, G Loers, M Prondzynski, O Pless, ... Journal of Biological Chemistry 288 (9), 6726-6742, 2013 | 52 | 2013 |
Chronic intermittent tachypacing by an optogenetic approach induces arrhythmia vulnerability in human engineered heart tissue M Lemme, I Braren, M Prondzynski, B Aksehirlioglu, BM Ulmer, ... Cardiovascular research 116 (8), 1487-1499, 2020 | 47 | 2020 |
Increased Reactive Oxygen Species–Mediated Ca2+/Calmodulin-Dependent Protein Kinase II Activation Contributes to Calcium Handling Abnormalities and … X Liu, S Wang, X Guo, Y Li, R Ogurlu, F Lu, M Prondzynski, ... Circulation 143 (19), 1894-1911, 2021 | 43 | 2021 |
Gene therapy for inherited arrhythmias VJ Bezzerides, M Prondzynski, L Carrier, WT Pu Cardiovascular Research 116 (9), 1635-1650, 2020 | 25 | 2020 |
ACTN2 Mutant Causes Proteopathy in Human iPSC-Derived Cardiomyocytes ATL Zech, M Prondzynski, SR Singh, N Pietsch, E Orthey, E Alizoti, ... Cells 11 (17), 2745, 2022 | 14 | 2022 |
In vivo dissection of chamber-selective enhancers reveals estrogen-related receptor as a regulator of ventricular cardiomyocyte identity Y Cao, X Zhang, BN Akerberg, H Yuan, T Sakamoto, F Xiao, ... Circulation 147 (11), 881-896, 2023 | 13 | 2023 |
Case Report on: Very Early Afterdepolarizations in HiPSC-Cardiomyocytes—An Artifact by Big Conductance Calcium Activated Potassium Current (Ibk,Ca) A Horváth, T Christ, JT Koivumäki, M Prondzynski, ATL Zech, M Spohn, ... Cells 9 (1), 253, 2020 | 11 | 2020 |
Mechanistic role of the CREB-regulated transcription coactivator 1 in cardiac hypertrophy K Morhenn, T Quentin, H Wichmann, M Steinmetz, M Prondzynski, ... Journal of molecular and cellular cardiology 127, 31-43, 2019 | 8 | 2019 |
Low‐Fouling Zwitterionic Polymeric Colloids as Resuscitation Fluids for Hemorrhagic Shock R Kumar, JG Mancebo, R Patenaude, K Sack, M Prondzynski, ... Advanced Materials 34 (47), 2207376, 2022 | 4 | 2022 |
Tbx5 maintains atrial identity in postnatal cardiomyocytes by regulating an atrial-specific enhancer network ME Sweat, Y Cao, X Zhang, O Burnicka-Turek, C Perez-Cervantes, ... Nature Cardiovascular Research 2 (10), 881-898, 2023 | 1 | 2023 |
Advances in pluripotent stem cell-based in vitro models of the human heart for cardiac physiology, disease modeling and clinical applications M Prondzynski, JM Pioner, L Sala, M Bellin, V Meraviglia Frontiers in Physiology 15, 1378495, 2024 | | 2024 |