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Jakob Franke
Jakob Franke
Associate Professor (Tenure Track), Leibniz University Hannover
Verified email at botanik.uni-hannover.de - Homepage
Title
Cited by
Cited by
Year
Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle
L Caputi, J Franke, SC Farrow, K Chung, RME Payne, TD Nguyen, ...
Science 360 (6394), 1235-1239, 2018
3002018
Genomics‐Driven Discovery of Burkholderic Acid, a Noncanonical, Cryptic Polyketide from Human Pathogenic Burkholderia Species
J Franke, K Ishida, C Hertweck
Angewandte Chemie 124 (46), 11779-11783, 2012
1312012
Terpenoid biosynthesis off the beaten track: unconventional cyclases and their impact on biomimetic synthesis
M Baunach, J Franke, C Hertweck
Angewandte Chemie International Edition 54 (9), 2604-2626, 2015
1202015
A three enzyme system to generate the Strychnos alkaloid scaffold from a central biosynthetic intermediate
EC Tatsis, I Carqueijeiro, T Dugé de Bernonville, J Franke, TTT Dang, ...
Nature communications 8 (1), 316, 2017
1132017
Biomimetic thioesters as probes for enzymatic assembly lines: synthesis, applications, and challenges
J Franke, C Hertweck
Cell Chemical Biology 23 (10), 1179-1192, 2016
892016
Gene Discovery in Gelsemium Highlights Conserved Gene Clusters in Monoterpene Indole Alkaloid Biosynthesis
J Franke, J Kim, JP Hamilton, D Zhao, GM Pham, K Wiegert‐Rininger, ...
ChemBioChem 20 (1), 83-87, 2019
802019
Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes
TTT Dang, J Franke, IST Carqueijeiro, C Langley, V Courdavault, ...
Nature chemical biology 14 (8), 760-763, 2018
552018
Nitro versus hydroxamate in siderophores of pathogenic bacteria: effect of missing hydroxylamine protection in malleobactin biosynthesis.
J Franke, K Ishida, M Ishida‐Ito, C Hertweck
Angewandte Chemie 125 (32), 2013
542013
A pair of bacterial siderophores releases and traps an intercellular signal molecule: An unusual case of natural nitrone bioconjugation
F Trottmann, J Franke, K Ishida, M García‐Altares, C Hertweck
Angewandte Chemie International Edition 58 (1), 200-204, 2019
382019
Dual Catalytic Activity of a Cytochrome P450 Controls Bifurcation at a Metabolic Branch Point of Alkaloid Biosynthesis in Rauwolfia serpentina
TTT Dang, J Franke, E Tatsis, SE O'Connor
Angewandte Chemie 129 (32), 9568-9572, 2017
382017
Cyclopropanol Warhead in Malleicyprol Confers Virulence of Human‐ and Animal‐Pathogenic Burkholderia Species
F Trottmann, J Franke, I Richter, K Ishida, M Cyrulies, HM Dahse, ...
Angewandte Chemie International Edition 58 (40), 14129-14133, 2019
322019
Biosynthetic code for divergolide assembly in a bacterial mangrove endophyte
Z Xu, M Baunach, L Ding, H Peng, J Franke, C Hertweck
ChemBioChem 15 (9), 1274-1279, 2014
312014
Structural basis of cycloaddition in biosynthesis of iboga and aspidosperma alkaloids
L Caputi, J Franke, K Bussey, SC Farrow, IJC Vieira, CEM Stevenson, ...
Nature chemical biology 16 (4), 383-386, 2020
292020
Plasticity of the malleobactin pathway and its impact on siderophore action in human pathogenic bacteria
J Franke, K Ishida, C Hertweck
Chemistry–A European Journal 21 (22), 8010-8014, 2015
282015
Evolution of siderophore pathways in human pathogenic bacteria
J Franke, K Ishida, C Hertweck
Journal of the American Chemical Society 136 (15), 5599-5602, 2014
262014
Dugé de Bernonville T, Ameyaw B, Jones DM, Vieira IJC, Courdavault V, O’Connor SE (2018) Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar …
L Caputi, J Franke, SC Farrow, K Chung, RME Payne, TD Nguyen, ...
Science 360 (6394), 1235-1239, 0
26
Sulfonium Acids Loaded onto an Unusual Thiotemplate Assembly Line Construct the Cyclopropanol Warhead of a Burkholderia Virulence Factor
F Trottmann, K Ishida, J Franke, A Stanišić, M Ishida‐Ito, H Kries, ...
Angewandte Chemie 132 (32), 13613-13617, 2020
242020
Divergolide congeners illuminate alternative reaction channels for ansamycin diversification
L Ding, J Franke, C Hertweck
Organic & Biomolecular Chemistry 13 (6), 1618-1623, 2015
232015
Terpenoid‐Biosynthese abseits bekannter Wege: unkonventionelle Cyclasen und ihre Bedeutung für die biomimetische Synthese
M Baunach, J Franke, C Hertweck
Angewandte Chemie 127 (9), 2640-2664, 2015
172015
Isolation and characterisation of irinans, androstane-type withanolides from Physalis peruviana L.
A Stein, D Compera, B Karge, M Brönstrup, J Franke
Beilstein Journal of Organic Chemistry 15 (1), 2003-2012, 2019
142019
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