| Systematic structure modifications of multitarget prostate cancer drug candidate galeterone to produce novel androgen receptor down-regulating agents as an approach to … P Purushottamachar, AM Godbole, LK Gediya, MS Martin, TS Vasaitis, ... Journal of medicinal chemistry 56 (12), 4880-4898, 2013 | 126 | 2013 |
| Synthesis and biological evaluations of putative metabolically stable analogs of VN/124-1 (TOK-001): head to head anti-tumor efficacy evaluation of VN/124-1 (TOK-001) and … RD Bruno, TS Vasaitis, LK Gediya, P Purushottamachar, AM Godbole, ... Steroids 76 (12), 1268-1279, 2011 | 96 | 2011 |
| Autophagy inhibition synergistically enhances anticancer efficacy of RAMBA, VN/12-1 in SKBR-3 cells, and tumor xenografts AM Godbole, P Purushottamachar, MS Martin, C Daskalakis, VCO Njar Molecular cancer therapeutics 11 (4), 898-908, 2012 | 18 | 2012 |
| New insights into the androgen-targeted therapies and epigenetic therapies in prostate cancer AM Godbole, VCO Njar Prostate Cancer 2011, 2011 | 18 | 2011 |
| VN/14-1 induces ER stress and autophagy in HP-LTLC human breast cancer cells and has excellent oral pharmacokinetic profile in female Sprague Dawley rats AM Godbole, S Ramalingam, VP Ramamurthy, A Khandelwal, RD Bruno, ... European journal of pharmacology 734, 98-104, 2014 | 8 | 2014 |
| Androgen receptor down-regulating agents and uses thereof VCO Njar, LK Gediya, P Purushottamachar, A Godbole, A Kwegyir-Afful, ... US Patent 9,439,912, 2016 | 7 | 2016 |
| Murine toxicology and pharmacokinetics evaluation of retinoic acid metabolism blocking agent (RAMBA), VN/12-1 AM Godbole, P Purushottamachar, MS Martin, VCO Njar Cancer chemotherapy and pharmacology 70, 339-344, 2012 | 5 | 2012 |
| Anti-tumor effects of a novel retinoic acid metabolism blocking agent VN/14-1 in the N-methyl-N-nitrosourea-induced rat mammary carcinoma model and its effects … PE Goss, S Qi, H Hu, LK Gediya, P Purushottamachar, AM Godbole, ... Breast cancer research and treatment 133, 137-144, 2012 | 2 | 2012 |
| Prostate Cancer: Current and Emerging Therapies AM Godbole, VCO Njar Current Cancer Treatment-Novel Beyond Conventional Approaches, 2011 | 1 | 2011 |
| Mechanisms of Action and Efficacy Modulation of Novel Retinoic Acid Metabolism Blocking Agent (RAMBA) VN/12-1 in Estrogen Receptor-α Negative Breast Cancer Model Systems … AM Godbole University of Maryland, Baltimore, 2011 | 1 | 2011 |
| AGENT FOR ANDROGEN RECEPTOR DOWNWARD CONTROL AND USES THEREOF VCO Njar, LK Gediya, P Purushottamachar, A Godbole, A Kwegyir-Afful, ... | | 2016 |
| Androgen receptor down-regulating agents and uses thereof VCO Njar, LK Gediya, P Purushottamachar, A GODBOLE, ... | | 2014 |
| Development of second generation atypical RAMBAs for triple negative breast cancer therapy LK Gediya, AM Godbole, S Ramlingam, M Law, MS Martin, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 244, 2012 | | 2012 |
| Autophagy Inhibition Synergistically Enhances Anticancer Efficacy of RAMBA, VN/12-1 in SKBR-3 Cells, and Tumor XenograftsEfficacy Modulation of RAMBAs by Autophagy Inhibition AM Godbole, P Purushottamachar, MS Martin, C Daskalakis, VCO Njar Molecular cancer therapeutics 11 (4), 898-908, 2012 | | 2012 |
| Exploitation of multitarget prostate cancer clinical candidate VN/124-1 (TOK-001) to develop a novel class of androgen receptor down regulating agents for prostate cancer therapy PP Puranik, AM Godbole, LK Gediya, Z Ates-Alagoz, VCO Njar ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 242, 2011 | | 2011 |
| Inhibiting autophagy improves the efficacy of VN/12-1 over all-trans retinoic acid in a HER2 over-expressing SK-BR3 breast cancer xenograft model AM Godbole, P Purushottamachar, L Gediya, VCO Njar Cancer Research 71 (8_Supplement), 659-659, 2011 | | 2011 |
| Abstract LB-340: Inhibition of autophagy enhances the anticancer activity of the retinoic acid derivative VN/12-1 in endocrine resistant human breast cancer cell lines AM Godbole, P Purushottamachar, LK Gediya, VCO Njar Cancer Research 70 (8_Supplement), LB-340-LB-340, 2010 | | 2010 |
| Inhibition of autophagy enhances the anticancer activity of the retinoic acid derivative VN/12-1 in endocrine resistant human breast cancer cell lines AM Godbole, P Purushottamachar, LK Gediya, VCO Njar CANCER RESEARCH 70, 2010 | | 2010 |
| RAMBAs for Breast Cancer Prevention and Treatment VC Njar, J Mehta, LK Gediya, A Khandelwa, A Godbole, P Puranik, ... | | 2009 |
| 27 INVITED Novel atypical retinoic acid metabolism blocking agents (RAMBAs)/CYP26 inhibitors for breast cancer therapy LK Gediya, P Purushottamachar, A Khandelwal, J Mehta, A Godbole, ... Ejc Supplements 12 (6), 12, 2008 | | 2008 |
