Seek & Destroy, use of targeting peptides for cancer detection and drug delivery V Le Joncour, P Laakkonen Bioorganic & medicinal chemistry 26 (10), 2797-2806, 2018 | 104 | 2018 |
A novel anti-HER2 antibody–drug conjugate XMT-1522 for HER2-positive breast and gastric cancers resistant to trastuzumab emtansine V Le Joncour, A Martins, M Puhka, J Isola, M Salmikangas, P Laakkonen, ... Molecular cancer therapeutics 18 (10), 1721-1730, 2019 | 60 | 2019 |
ARX788, a novel anti-HER2 antibody-drug conjugate, shows anti-tumor effects in preclinical models of trastuzumab emtansine-resistant HER2-positive breast cancer and gastric cancer M Barok, V Le Joncour, A Martins, J Isola, M Salmikangas, P Laakkonen, ... Cancer letters 473, 156-163, 2020 | 58 | 2020 |
Selenoprotein T deficiency leads to neurodevelopmental abnormalities and hyperactive behavior in mice MT Castex, A Arabo, M Bénard, V Roy, V Le Joncour, G Prévost, ... Molecular neurobiology 53, 5818-5832, 2016 | 48 | 2016 |
Neuroprotective effects of PACAP against ethanol-induced toxicity in the developing rat cerebellum B Botia, V Jolivel, D Burel, V Le Joncour, V Roy, M Naassila, M Bénard, ... Neurotoxicity research 19, 423-434, 2011 | 45 | 2011 |
Vulnerability of invasive glioblastoma cells to lysosomal membrane destabilization V Le Joncour, P Filppu, M Hyvönen, M Holopainen, SP Turunen, H Sihto, ... EMBO molecular medicine 11 (6), e9034, 2019 | 44 | 2019 |
Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression J Eriksson, V Le Joncour, P Nummela, T Jahkola, S Virolainen, ... Oncotarget 7 (12), 15065, 2016 | 42 | 2016 |
Chemotactic G protein-coupled receptors control cell migration by repressing autophagosome biogenesis PM Coly, N Perzo, V Le Joncour, C Lecointre, MT Schouft, L Desrues, ... Autophagy 12 (12), 2344-2362, 2016 | 34 | 2016 |
Monotherapy efficacy of blood–brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma J Merisaari, OV Denisova, M Doroszko, V Le Joncour, P Johansson, ... Brain Communications 2 (1), fcaa002, 2020 | 30 | 2020 |
CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity P Filppu, JT Ramanathan, KJ Granberg, E Gucciardo, H Haapasalo, ... JCI insight 6 (9), 2021 | 27 | 2021 |
Impact of meriolins, a new class of cyclin-dependent kinase inhibitors, on malignant glioma proliferation and neo-angiogenesis M Jarry, C Lecointre, C Malleval, L Desrues, MT Schouft, V Lejoncour, ... Neuro-oncology 16 (11), 1484-1498, 2014 | 27 | 2014 |
Octreotide conjugates for tumor targeting and imaging E Figueras, A Martins, A Borbély, V Le Joncour, P Cordella, R Perego, ... Pharmaceutics 11 (5), 220, 2019 | 25 | 2019 |
Signaling switch of the urotensin II vasosactive peptide GPCR: prototypic chemotaxic mechanism in glioma C Lecointre, L Desrues, JE Joubert, N Perzo, PO Guichet, V Le Joncour, ... Oncogene 34 (39), 5080-5094, 2015 | 25 | 2015 |
Prolyl 4‐hydroxylase subunit alpha 1 (P4HA1) is a biomarker of poor prognosis in primary melanomas, and its depletion inhibits melanoma cell invasion and disrupts tumor blood … J Eriksson, V Le Joncour, T Jahkola, S Juteau, P Laakkonen, O Saksela, ... Molecular oncology 14 (4), 742-762, 2020 | 21 | 2020 |
Synthesis and biological evaluation of a novel 99mTc labeled 2-nitroimidazole derivative as a potential agent for imaging tumor hypoxia Y Joyard, V Le Joncour, H Castel, CB Diouf, L Bischoff, C Papamicaël, ... Bioorganic & Medicinal Chemistry Letters 23 (13), 3704-3708, 2013 | 19 | 2013 |
Evaluation of the impact of the cancer therapy everolimus on the central nervous system in mice M Dubois, V Le Joncour, MC Tonon, Y Anouar, F Proust, F Morin, ... PloS one 9 (12), e113533, 2014 | 16 | 2014 |
Predicting in vivo payloads delivery using a blood-brain tumor-barrier in a dish V Le Joncour, S Karaman, PM Laakkonen JoVE (Journal of Visualized Experiments), e59384, 2019 | 15 | 2019 |
Prostate‐specific membrane antigen expression in the vasculature of primary lung carcinomas associates with faster metastatic dissemination to the brain J Tanjore Ramanathan, S Lehtipuro, H Sihto, J Tóvári, L Reiniger, ... Journal of cellular and molecular medicine 24 (12), 6916-6927, 2020 | 13 | 2020 |
Synthesis, Biological Evaluation, and in Vivo Imaging of the first Camptothecin–Fluorescein Conjugate A Chevalier, M Dubois, V Le Joncour, S Dautrey, C Lecointre, A Romieu, ... Bioconjugate chemistry 24 (7), 1119-1133, 2013 | 10 | 2013 |
Circumventing drug treatment? Intrinsic lethal effects of polyethyleneimine (pei)-functionalized nanoparticles on glioblastoma cells cultured in stem cell conditions N Prabhakar, J Merisaari, V Le Joncour, M Peurla, DŞ Karaman, E Casals, ... Cancers 13 (11), 2631, 2021 | 9 | 2021 |