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| Chemistry and biology of taxol KC Nicolaou, WM Dai, RK Guy Angewandte Chemie International Edition in English 33 (1), 15-44, 1994 | 897 | 1994 |
| Inactivation of the p53 pathway in retinoblastoma NA Laurie, SL Donovan, CS Shih, J Zhang, N Mills, C Fuller, A Teunisse, ... Nature 444 (7115), 61-66, 2006 | 700 | 2006 |
| Chemical genetics of Plasmodium falciparum WA Guiguemde, AA Shelat, D Bouck, S Duffy, GJ Crowther, PH Davis, ... Nature 465 (7296), 311-315, 2010 | 644 | 2010 |
| Structural analyses reveal phosphatidyl inositols as ligands for the NR5 orphan receptors SF-1 and LRH-1 IN Krylova, EP Sablin, J Moore, RX Xu, GM Waitt, JA MacKay, ... Cell 120 (3), 343-355, 2005 | 482 | 2005 |
| High-throughput assays for promiscuous inhibitors BY Feng, A Shelat, TN Doman, RK Guy, BK Shoichet Nature chemical biology 1 (3), 146-148, 2005 | 412 | 2005 |
| Copper-mediated cross-coupling of aryl boronic acids and alkyl thiols PS Herradura, KA Pendola, RK Guy Organic Letters 2 (14), 2019-2022, 2000 | 397 | 2000 |
| Total synthesis of taxol. 2. Construction of A and C ring intermediates and initial attempts to construct the ABC ring system KC Nicolaou, JJ Liu, Z Yang, H Ueno, EJ Sorensen, CF Claiborne, ... Journal of the American Chemical society 117 (2), 634-644, 1995 | 351 | 1995 |
| A surface on the androgen receptor that allosterically regulates coactivator binding E Estébanez-Perpiñá, LA Arnold, P Nguyen, ED Rodrigues, E Mar, ... Proceedings of the National Academy of Sciences 104 (41), 16074-16079, 2007 | 347 | 2007 |
| Rapid repurposing of drugs for COVID-19 RK Guy, RS DiPaola, F Romanelli, RE Dutch Science 368 (6493), 829-830, 2020 | 308 | 2020 |
| Total synthesis of taxol. 1. Retrosynthesis, degradation, and reconstitution KC Nicolaou, PG Nantermet, H Ueno, RK Guy, EA Couladouros, ... Journal of the American Chemical society 117 (2), 624-633, 1995 | 301 | 1995 |
| Open source drug discovery with the malaria box compound collection for neglected diseases and beyond WC Van Voorhis, JH Adams, R Adelfio, V Ahyong, MH Akabas, P Alano, ... PLoS pathogens 12 (7), e1005763, 2016 | 294 | 2016 |
| Nanomolar affinity small molecule correctors of defective ΔF508-CFTR chloride channel gating H Yang, AA Shelat, RK Guy, VS Gopinath, T Ma, K Du, GL Lukacs, ... Journal of Biological Chemistry 278 (37), 35079-35085, 2003 | 264 | 2003 |
| An antagonist of dishevelled protein-protein interaction suppresses β-catenin–dependent tumor cell growth N Fujii, L You, Z Xu, K Uematsu, J Shan, B He, I Mikami, LR Edmondson, ... Cancer research 67 (2), 573-579, 2007 | 261 | 2007 |
| (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium MB Jiménez-Díaz, D Ebert, Y Salinas, A Pradhan, AM Lehane, ... Proceedings of the National Academy of Sciences 111 (50), E5455-E5462, 2014 | 259 | 2014 |
| MAGI-1, a membrane-associated guanylate kinase with a unique arrangement of protein-protein interaction domains I Dobrosotskaya, RK Guy, GL James Journal of Biological Chemistry 272 (50), 31589-31597, 1997 | 259 | 1997 |
| Total synthesis of taxol. 3. Formation of taxol's ABC ring skeleton KC Nicolaou, Z Yang, JJ Liu, PG Nantermet, CF Claiborne, J Renaud, ... Journal of the American Chemical society 117 (2), 645-652, 1995 | 254 | 1995 |
| High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening T Ma, L Vetrivel, H Yang, N Pedemonte, O Zegarra-Moran, LJV Galietta, ... Journal of Biological Chemistry 277 (40), 37235-37241, 2002 | 252 | 2002 |
| Quinolone-3-diarylethers: a new class of antimalarial drug A Nilsen, AN LaCrue, KL White, IP Forquer, RM Cross, J Marfurt, ... Science translational medicine 5 (177), 177ra37-177ra37, 2013 | 245 | 2013 |
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Kyriacos NicolaouRice UniversityVerified email at rice.edu
