| Engineered alterations in RNA editing modulate complex behavior in Drosophila: regulatory diversity of adenosine deaminase acting on RNA (ADAR) targets JEC Jepson, YA Savva, C Yokose, AU Sugden, A Sahin, RA Reenan Journal of biological chemistry 286 (10), 8325-8337, 2011 | 78 | 2011 |
| Human SOD1 ALS Mutations in a Drosophila Knock-In Model Cause Severe Phenotypes and Reveal Dosage-Sensitive Gain- and Loss-of-Function Components. GSRR Asli Şahin, Aaron Held, Kirsten Bredvik, Paxton Major, Toni-Marie ... Genetics 205 (2), 707-723, 2017 | 59 | 2017 |
| Auto-regulatory RNA editing fine-tunes mRNA re-coding and complex behaviour in Drosophila YA Savva, JEC Jepson, A Sahin, AU Sugden, JS Dorsky, L Alpert, ... Nature communications 3 (1), 790, 2012 | 55 | 2012 |
| Circuit dysfunction in SOD1-ALS model first detected in sensory feedback prior to motor neuron degeneration is alleviated by BMP signaling A Held, P Major, A Sahin, RA Reenan, D Lipscombe, KA Wharton Journal of Neuroscience 39 (12), 2347-2364, 2019 | 37 | 2019 |
| Genome-encoded cytoplasmic double-stranded RNAs, found in C9ORF72 ALS-FTD brain, propagate neuronal loss S Rodriguez, A Sahin, BR Schrank, H Al-Lawati, I Costantino, E Benz, ... Science translational medicine 13 (601), eaaz4699, 2021 | 32 | 2021 |
| Age-dependent degeneration of an identified adult leg motor neuron in a Drosophila SOD1 model of ALS A Agudelo, V St. Amand, L Grissom, D Lafond, T Achilli, A Sahin, ... Biology open 9 (10), bio049692, 2020 | 6 | 2020 |
| Genome-encoded cytoplasmic double-stranded RNAs, found in C9ORF72 ALS-FTD brain, provoke propagated neuronal death S Rodriguez, BR Schrank, A Sahin, H Al-Lawati, I Costantino, E Benz, ... BioRxiv, 248328, 2018 | 6 | 2018 |
| Auto-regulatory RNA editing fine-tunes mRNA re-coding and complex behaviour in YA Savva, JEC Jepson, A Sahin, AU Sugden, JS Dorsky, L Alpert, ... Drosophila. Nat Commun 3, 2012 | 6 | 2012 |
| From microbiome composition to functional engineering, one step at a time SD Burz, S Causevic, A Dal Co, M Dmitrijeva, P Engel, D Garrido-Sanz, ... Microbiology and Molecular Biology Reviews 87 (4), e00063-23, 2023 | 5 | 2023 |
| Optimal enzyme utilization suggests that concentrations and thermodynamics determine binding mechanisms and enzyme saturations A Sahin, DR Weilandt, V Hatzimanikatis Nature Communications 14 (1), 2618, 2023 | 4 | 2023 |
| Optimality principles for the analysis of biological processes across scales: From enzyme kinetics to microbiome dynamics A Sahin EPFL, 2024 | | 2024 |
| A constraint-based framework to reconstruct interaction networks in microbial communities O Oftadeh, A Sahin, E Vayena, V Hatzimanikatis bioRxiv, 2024.01. 30.577913, 2024 | | 2024 |
| Optimal enzyme utilization suggests concentrations and thermodynamics favor condition-specific saturations and binding mechanisms A Sahin, DR Weilandt, V Hatzimanikatis bioRxiv, 2022.04. 12.488028, 2022 | | 2022 |
| HUMAN-DERIVED MUTANTS OF THE dSOD1 GENE IN DROSOPHILA AND METHODS OF MAKING AND USING R Reenan US Patent App. 14/741,534, 2016 | | 2016 |
| LCSB S Andreozzi, L Angeles Martinez, P Angelino, M Ataman, Y Berset, ... | | |
