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Dennis Kostka
Dennis Kostka
Verified email at pitt.edu - Homepage
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Year
A high-resolution map of human evolutionary constraint using 29 mammals
K Lindblad-Toh, M Garber, O Zuk, MF Lin, BJ Parker, S Washietl, ...
Nature 478 (7370), 476-482, 2011
12422011
Regulatory networks define phenotypic classes of human stem cell lines
FJ Müller, LC Laurent, D Kostka, I Ulitsky, R Williams, C Lu, IH Park, ...
Nature 455 (7211), 401-405, 2008
3882008
Gibbon genome and the fast karyotype evolution of small apes
L Carbone, R Alan Harris, S Gnerre, KR Veeramah, B Lorente-Galdos, ...
Nature 513 (7517), 195-201, 2014
3552014
The complex genetics of hypoplastic left heart syndrome
X Liu, H Yagi, S Saeed, AS Bais, GC Gabriel, Z Chen, KA Peterson, Y Li, ...
Nature genetics 49 (7), 1152-1159, 2017
1972017
Finding disease specific alterations in the co-expression of genes
D Kostka, R Spang
Bioinformatics 20 (suppl_1), i194-i199, 2004
1822004
Integrating diverse datasets improves developmental enhancer prediction
GD Erwin, N Oksenberg, RM Truty, D Kostka, KK Murphy, N Ahituv, ...
PLoS computational biology 10 (6), e1003677, 2014
1812014
scds: Computational annotation of doublets in single-cell RNA sequencing data
AS Bais, D Kostka
Bioinformatics 36 (4), btz968, 2019
1622019
Nested effects models for high-dimensional phenotyping screens
F Markowetz, D Kostka, OG Troyanskaya, R Spang
Bioinformatics 23 (13), i305-i312, 2007
1242007
The role of GC-biased gene conversion in shaping the fastest evolving regions of the human genome
D Kostka, MJ Hubisz, A Siepel, KS Pollard
Molecular biology and evolution 29 (3), 1047-1057, 2012
1032012
Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment
H Liu, CH Zhang, N Ammanamanchi, S Suresh, C Lewarchik, K Rao, ...
Science translational medicine 11 (513), eaaw6419, 2019
842019
MicroRNA-17~ 92 is required for nephrogenesis and renal function
AK Marrone, DB Stolz, SI Bastacky, D Kostka, AJ Bodnar, J Ho
Journal of the American Society of Nephrology 25 (7), 1440-1452, 2014
822014
A model-based analysis of GC-biased gene conversion in the human and chimpanzee genomes
JA Capra, MJ Hubisz, D Kostka, KS Pollard, A Siepel
PLoS genetics 9 (8), e1003684, 2013
802013
DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans
FRG Amrit, EM Steenkiste, R Ratnappan, SW Chen, TB McClendon, ...
PLoS genetics 12 (2), e1005788, 2016
672016
The importance of being cis: evolution of orthologous fish and mammalian enhancer activity
DI Ritter, Q Li, D Kostka, KS Pollard, S Guo, JH Chuang
Molecular biology and evolution 27 (10), 2322-2332, 2010
642010
Expression of late cell cycle genes and an increased proliferative capacity characterize very early relapse of childhood acute lymphoblastic leukemia
R Kirschner-Schwabe, C Lottaz, J Tödling, P Rhein, L Karawajew, ...
Clinical cancer research 12 (15), 4553-4561, 2006
622006
Genome-wide enhancer annotations differ significantly in genomic distribution, evolution, and function
ML Benton, SC Talipineni, D Kostka, JA Capra
Bmc Genomics 20, 1-22, 2019
552019
Random forest based similarity learning for single cell RNA sequencing data
MB Pouyan, D Kostka
Bioinformatics, 34 (13), i79–i88, 2018
502018
Large-scale inference of competing endogenous RNA networks with sparse partial correlation
M List, A Dehghani Amirabad, D Kostka, MH Schulz
Bioinformatics 35 (14), i596-i604, 2019
402019
Microarray based diagnosis profits from better documentation of gene expression signatures
D Kostka, R Spang
PLoS computational biology 4 (2), e22, 2008
352008
Analyzing gene perturbation screens with nested effects models in R and bioconductor
H Fröhlich, T Beißbarth, A Tresch, D Kostka, J Jacob, R Spang, ...
Bioinformatics 24 (21), 2549-2550, 2008
312008
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