A high-resolution map of human evolutionary constraint using 29 mammals K Lindblad-Toh, M Garber, O Zuk, MF Lin, BJ Parker, S Washietl, ... Nature 478 (7370), 476-482, 2011 | 1243 | 2011 |
Regulatory networks define phenotypic classes of human stem cell lines FJ Müller, LC Laurent, D Kostka, I Ulitsky, R Williams, C Lu, IH Park, ... Nature 455 (7211), 401-405, 2008 | 388 | 2008 |
Gibbon genome and the fast karyotype evolution of small apes L Carbone, R Alan Harris, S Gnerre, KR Veeramah, B Lorente-Galdos, ... Nature 513 (7517), 195-201, 2014 | 356 | 2014 |
The complex genetics of hypoplastic left heart syndrome X Liu, H Yagi, S Saeed, AS Bais, GC Gabriel, Z Chen, KA Peterson, Y Li, ... Nature genetics 49 (7), 1152-1159, 2017 | 198 | 2017 |
Finding disease specific alterations in the co-expression of genes D Kostka, R Spang Bioinformatics 20 (suppl_1), i194-i199, 2004 | 182 | 2004 |
Integrating diverse datasets improves developmental enhancer prediction GD Erwin, N Oksenberg, RM Truty, D Kostka, KK Murphy, N Ahituv, ... PLoS computational biology 10 (6), e1003677, 2014 | 181 | 2014 |
scds: Computational annotation of doublets in single-cell RNA sequencing data AS Bais, D Kostka Bioinformatics 36 (4), btz968, 2019 | 163 | 2019 |
Nested effects models for high-dimensional phenotyping screens F Markowetz, D Kostka, OG Troyanskaya, R Spang Bioinformatics 23 (13), i305-i312, 2007 | 124 | 2007 |
The role of GC-biased gene conversion in shaping the fastest evolving regions of the human genome D Kostka, MJ Hubisz, A Siepel, KS Pollard Molecular biology and evolution 29 (3), 1047-1057, 2012 | 103 | 2012 |
Control of cytokinesis by β-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment H Liu, CH Zhang, N Ammanamanchi, S Suresh, C Lewarchik, K Rao, ... Science translational medicine 11 (513), eaaw6419, 2019 | 84 | 2019 |
MicroRNA-17~ 92 is required for nephrogenesis and renal function AK Marrone, DB Stolz, SI Bastacky, D Kostka, AJ Bodnar, J Ho Journal of the American Society of Nephrology 25 (7), 1440-1452, 2014 | 82 | 2014 |
A model-based analysis of GC-biased gene conversion in the human and chimpanzee genomes JA Capra, MJ Hubisz, D Kostka, KS Pollard, A Siepel PLoS genetics 9 (8), e1003684, 2013 | 80 | 2013 |
DAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegans FRG Amrit, EM Steenkiste, R Ratnappan, SW Chen, TB McClendon, ... PLoS genetics 12 (2), e1005788, 2016 | 67 | 2016 |
The importance of being cis: evolution of orthologous fish and mammalian enhancer activity DI Ritter, Q Li, D Kostka, KS Pollard, S Guo, JH Chuang Molecular biology and evolution 27 (10), 2322-2332, 2010 | 64 | 2010 |
Expression of late cell cycle genes and an increased proliferative capacity characterize very early relapse of childhood acute lymphoblastic leukemia R Kirschner-Schwabe, C Lottaz, J Tödling, P Rhein, L Karawajew, ... Clinical cancer research 12 (15), 4553-4561, 2006 | 62 | 2006 |
Genome-wide enhancer annotations differ significantly in genomic distribution, evolution, and function ML Benton, SC Talipineni, D Kostka, JA Capra Bmc Genomics 20, 1-22, 2019 | 55 | 2019 |
Random forest based similarity learning for single cell RNA sequencing data MB Pouyan, D Kostka Bioinformatics, 34 (13), i79–i88, 2018 | 50 | 2018 |
Large-scale inference of competing endogenous RNA networks with sparse partial correlation M List, A Dehghani Amirabad, D Kostka, MH Schulz Bioinformatics 35 (14), i596-i604, 2019 | 41 | 2019 |
Microarray based diagnosis profits from better documentation of gene expression signatures D Kostka, R Spang PLoS computational biology 4 (2), e22, 2008 | 35 | 2008 |
Analyzing gene perturbation screens with nested effects models in R and bioconductor H Fröhlich, T Beißbarth, A Tresch, D Kostka, J Jacob, R Spang, ... Bioinformatics 24 (21), 2549-2550, 2008 | 31 | 2008 |