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Lan Lan
Lan Lan
Verified email at ku.edu
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Year
Identification and validation of novel small molecule disruptors of HuR-mRNA interaction
X Wu, L Lan, DM Wilson, RT Marquez, W Tsao, P Gao, A Roy, BA Turner, ...
ACS chemical biology 10 (6), 1476-1484, 2015
1492015
Natural product (−)-gossypol inhibits colon cancer cell growth by targeting RNA-binding protein Musashi-1
L Lan, C Appelman, AR Smith, J Yu, S Larsen, RT Marquez, H Liu, X Wu, ...
Molecular oncology 9 (7), 1406-1420, 2015
1312015
Tumor suppressive microRNA-137 negatively regulates Musashi-1 and colorectal cancer progression
AR Smith, RT Marquez, WC Tsao, S Pathak, A Roy, J Ping, B Wilkerson, ...
Oncotarget 6 (14), 12558, 2015
792015
Rab11 maintains connections between germline stem cells and niche cells in the Drosophila ovary
N Bogard, L Lan, J Xu, RS Cohen
Oxford University Press for The Company of Biologists Limited 134 (19), 3413 …, 2007
762007
Targeting the interaction between RNA-binding protein HuR and FOXQ1 suppresses breast cancer invasion and metastasis
X Wu, G Gardashova, L Lan, S Han, C Zhong, RT Marquez, L Wei, ...
Communications biology 3 (1), 193, 2020
742020
The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro
K Kaur, X Wu, JK Fields, DK Johnson, L Lan, M Pratt, AD Somoza, ...
PLoS One 12 (4), e0175471, 2017
482017
Natural product derivative Gossypolone inhibits Musashi family of RNA-binding proteins
L Lan, H Liu, AR Smith, C Appelman, J Yu, S Larsen, RT Marquez, X Wu, ...
BMC cancer 18, 1-14, 2018
422018
Double-layered hyaluronic acid/stearic acid-modified polyethyleneimine nanoparticles encapsulating (−)-gossypol: a nanocarrier for chiral anticancer drugs
H Liu, K Li, L Lan, J Ma, Y Zeng, L Xu, D Wu
Journal of materials chemistry B 2 (32), 5238-5248, 2014
402014
MicroRNA‐383 acts as a tumor suppressor in colorectal cancer by modulating CREPT/RPRD1B expression
J Li, AR Smith, RT Marquez, J Li, K Li, L Lan, X Wu, L Zhao, F Ren, ...
Molecular carcinogenesis 57 (10), 1408-1420, 2018
332018
DARC: mapping surface topography by ray-casting for effective virtual screening at protein interaction sites
R Gowthaman, SA Miller, S Rogers, J Khowsathit, L Lan, N Bai, ...
Journal of medicinal chemistry 59 (9), 4152-4170, 2016
252016
Identification of novel small molecule Beclin 1 mimetics activating autophagy
J Yu, L Lan, SJ Lewin, SA Rogers, A Roy, X Wu, P Gao, J Karanicolas, ...
Oncotarget 8 (31), 51355, 2017
192017
Mechanism of RNA recognition by a Musashi RNA-binding protein
J Wang, L Lan, X Wu, L Xu, Y Miao
Current Research in Structural Biology 4, 10-20, 2022
172022
Identification and Validation of an Aspergillus nidulans Secondary Metabolite Derivative as an Inhibitor of the Musashi-RNA Interaction
L Lan, J Liu, M Xing, AR Smith, J Wang, X Wu, C Appelman, K Li, A Roy, ...
Cancers 12 (8), 2221, 2020
172020
Evidence for a transport-trap mode of Drosophila melanogaster gurken mRNA localization
L Lan, S Lin, S Zhang, RS Cohen
PLoS One 5 (11), e15448, 2010
172010
Rab11 Is Required for Epithelial Cell Viability, Terminal Differentiation, and Suppression of Tumor-Like Growth in the Drosophila Egg Chamber
J Xu, L Lan, N Bogard, C Mattione, RS Cohen
PloS one 6 (5), e20180, 2011
152011
Human oncoprotein Musashi-2 N-terminal RNA recognition motif backbone assignment and identification of RNA-binding pocket
L Lan, M Xing, JT Douglas, P Gao, RP Hanzlik, L Xu
Oncotarget 8 (63), 106587, 2017
132017
Crystal and solution structures of human oncoprotein Musashi‐2 N‐terminal RNA recognition motif 1
L Lan, M Xing, M Kashipathy, J Douglas, P Gao, K Battaile, R Hanzlik, ...
Proteins: Structure, Function, and Bioinformatics 88 (4), 573-583, 2020
92020
Small molecules targeting the RNA-binding protein HuR inhibit tumor growth in xenografts
X Wu, R Ramesh, J Wang, Y Zheng, AM Armaly, L Wei, M Xing, S Roy, ...
Journal of medicinal chemistry 66 (3), 2032-2053, 2023
82023
Identification and validation of novel small molecule disruptors of HuR-mRNA interaction, ACS Chem
X Wu, L Lan, DM Wilson, RT Marquez, WC Tsao, P Gao, A Roy, BA Turner, ...
Biol 10, 1476-1484, 2015
62015
Tumor suppressor miR-137 inhibits colorectal cancer progression by negatively regulating cancer stem cell marker, Musashi-1
AR Smith, R Marquez, B Tsao, L Lan, S Pathak, XF Sun, K Neufeld, L Xu
Cancer Research 74 (19_Supplement), 1460-1460, 2014
32014
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