| Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS PEA Ash, KF Bieniek, TF Gendron, T Caulfield, WL Lin, ... Neuron 77 (4), 639-646, 2013 | 1191 | 2013 |
| The high-affinity HSP90-CHIP complex recognizes and selectively degrades phosphorylated tau client proteins CA Dickey, A Kamal, K Lundgren, N Klosak, RM Bailey, J Dunmore, P Ash, ... The Journal of clinical investigation 117 (3), 648-658, 2007 | 756 | 2007 |
| Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity YJ Zhang, YF Xu, C Cook, TF Gendron, P Roettges, CD Link, WL Lin, ... Proceedings of the National Academy of Sciences 106 (18), 7607-7612, 2009 | 669 | 2009 |
| Antisense transcripts of the expanded C9ORF72 hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS TF Gendron, KF Bieniek, YJ Zhang, K Jansen-West, PEA Ash, T Caulfield, ... Acta neuropathologica 126 (6), 829-844, 2013 | 619 | 2013 |
| Aggregation-prone c9FTD/ALS poly (GA) RAN-translated proteins cause neurotoxicity by inducing ER stress YJ Zhang, K Jansen-West, YF Xu, TF Gendron, KF Bieniek, WL Lin, ... Acta neuropathologica 128 (4), 505-524, 2014 | 383 | 2014 |
| Interaction of tau with the RNA-binding protein TIA1 regulates tau pathophysiology and toxicity T Vanderweyde, DJ Apicco, K Youmans-Kidder, PEA Ash, C Cook, ... Cell reports 15 (7), 1455-1466, 2016 | 287 | 2016 |
| Neurotoxic effects of TDP-43 overexpression in C. elegans PEA Ash, YJ Zhang, CM Roberts, T Saldi, H Hutter, E Buratti, L Petrucelli, ... Human molecular genetics 19 (16), 3206-3218, 2010 | 283 | 2010 |
| Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo DJ Apicco, PEA Ash, B Maziuk, C LeBlang, M Medalla, A Al Abdullatif, ... Nature neuroscience 21 (1), 72, 2018 | 217 | 2018 |
| Pathological stress granules in Alzheimer’s disease PEA Ash, TE Vanderweyde, KL Youmans, DJ Apicco, B Wolozin Brain research 1584, 52-58, 2014 | 128 | 2014 |
| C9ORF72 repeat expansions in cases with previously identified pathogenic mutations M Van Blitterswijk, MC Baker, M DeJesus-Hernandez, R Ghidoni, ... Neurology 81 (15), 1332-1341, 2013 | 110 | 2013 |
| TDP-1/TDP-43 regulates stress signaling and age-dependent proteotoxicity in Caenorhabditis elegans A Vaccaro, A Tauffenberger, PEA Ash, Y Carlomagno, L Petrucelli, ... PLoS genetics 8 (7), e1002806, 2012 | 95 | 2012 |
| TDP‐1, the Caenorhabditis elegans ortholog of TDP‐43, limits the accumulation of double‐stranded RNA TK Saldi, PEA Ash, G Wilson, P Gonzales, A Garrido‐Lecca, CM Roberts, ... The EMBO journal, e201488740, 2014 | 76 | 2014 |
| Mutations in LRRK2 potentiate age-related impairment of autophagic flux S Saha, PEA Ash, V Gowda, L Liu, O Shirihai, B Wolozin Molecular neurodegeneration 10 (1), 26, 2015 | 64 | 2015 |
| Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression CA Dickey, P Ash, N Klosak, WC Lee, L Petrucelli, M Hutton, CB Eckman Molecular neurodegeneration 1 (1), 6, 2006 | 49 | 2006 |
| Heavy metal neurotoxicants induce ALS-linked TDP-43 pathology PEA Ash, U Dhawan, S Boudeau, S Lei, Y Carlomagno, M Knobel, ... Toxicological Sciences 167 (1), 105-115, 2018 | 48 | 2018 |
| Dioxins and related environmental contaminants increase TDP-43 levels PEA Ash, EA Stanford, A Al Abdulatif, A Ramirez-Cardenas, HI Ballance, ... Molecular neurodegeneration 12 (1), 35, 2017 | 37 | 2017 |
| Progressive amnestic dementia, hippocampal sclerosis, and mutation in C9ORF72 ME Murray, KF Bieniek, MB Greenberg, M DeJesus-Hernandez, ... Acta neuropathologica 126 (4), 545-554, 2013 | 36 | 2013 |
| Methods and materials for detecting C9ORF72 hexanucleotide repeat expansion positive frontotemporal lobar degeneration or C9ORF72 hexanucleotide repeat expansion positive … L Petrucelli, PE Ash, T Gendron US Patent 9,448,232, 2016 | 16 | 2016 |
| Methods and materials for detecting c9orf72 hexanucleotide repeat expansion positive frontotemporal lobar degeneration or c9orf72 hexanucleotide repeat expansion positive … L Petrucelli, PE Ash, T Gendron US Patent App. 15/246,267, 2017 | 3 | 2017 |
| TAU-INDUCED NEURODEGENERATION IS MEDIATED BY RNA BINDING PROTEINS B Wolozin, DJ Apicco, C Zhang, PEA Ash, B Maziuk, A Al Abdullatif, ... Alzheimer's & Dementia: The Journal of the Alzheimer's Association 13 (7 …, 2017 | | 2017 |
