Defined engineered human myocardium with advanced maturation for applications in heart failure modeling and repair M Tiburcy, JE Hudson, P Balfanz, S Schlick, T Meyer, ML Chang Liao, ... Circulation 135 (19), 1832-1847, 2017 | 607 | 2017 |
Circadian clocks: from stem cells to tissue homeostasis and regeneration P Dierickx, LW Van Laake, N Geijsen EMBO reports 19 (1), 18-28, 2018 | 141 | 2018 |
SR9009 has REV-ERB–independent effects on cell proliferation and metabolism P Dierickx, MJ Emmett, C Jiang, K Uehara, M Liu, M Adlanmerini, ... Proceedings of the National Academy of Sciences 116 (25), 12147-12152, 2019 | 134 | 2019 |
The nuclear receptor ESRRA protects from kidney disease by coupling metabolism and differentiation P Dhillon, J Park, CH Del Pozo, L Li, T Doke, S Huang, J Zhao, HM Kang, ... Cell metabolism 33 (2), 379-394. e8, 2021 | 126 | 2021 |
The hepatocyte clock and feeding control chronophysiology of multiple liver cell types D Guan, Y Xiong, TM Trinh, Y Xiao, W Hu, C Jiang, P Dierickx, C Jang, ... Science 369 (6509), 1388-1394, 2020 | 121 | 2020 |
Circadian networks in human embryonic stem cell‐derived cardiomyocytes P Dierickx, MW Vermunt, MJ Muraro, MP Creyghton, PA Doevendans, ... EMBO reports 18 (7), 1199-1212, 2017 | 82 | 2017 |
Bright bioluminescent BRET sensor proteins for measuring intracellular caspase activity A den Hamer, P Dierickx, R Arts, JSPM de Vries, L Brunsveld, M Merkx ACS sensors 2 (6), 729-734, 2017 | 67 | 2017 |
Dual readout BRET/FRET sensors for measuring intracellular zinc SJA Aper, P Dierickx, M Merkx ACS chemical biology 11 (10), 2854-2864, 2016 | 65 | 2016 |
The ROSA26-iPSC mouse: a conditional, inducible, and exchangeable resource for studying cellular (De) differentiation L Haenebalcke, S Goossens, P Dierickx, S Bartunkova, J D’Hont, K Haigh, ... Cell reports 3 (2), 335-341, 2013 | 49 | 2013 |
Efficient ROSA26-based conditional and/or inducible transgenesis using RMCE-compatible F1 hybrid mouse embryonic stem cells L Haenebalcke, S Goossens, M Naessens, N Kruse, MF Ghahremani, ... Stem Cell Reviews and Reports 9, 774-785, 2013 | 44 | 2013 |
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function P Dierickx, K Zhu, BJ Carpenter, C Jiang, MW Vermunt, Y Xiao, ... Nature cardiovascular research 1 (1), 45-58, 2022 | 38 | 2022 |
Neonatal rat cardiomyocytes as an in vitro model for circadian rhythms in the heart BC du Pré, P Dierickx, S Crnko, PA Doevendans, MA Vos, N Geijsen, ... Journal of molecular and cellular cardiology 112, 58-63, 2017 | 37 | 2017 |
Patient adipose stem cell-derived adipocytes reveal genetic variation that predicts antidiabetic drug response W Hu, C Jiang, D Guan, P Dierickx, R Zhang, A Moscati, GN Nadkarni, ... Cell Stem Cell 24 (2), 299-308. e6, 2019 | 31 | 2019 |
SCA1+ cells from the heart possess a molecular circadian clock and display circadian oscillations in cellular functions BC Du Pré, EJ Demkes, DAM Feyen, P Dierickx, S Crnko, BJM Kok, ... Stem Cell Reports 9 (3), 762-769, 2017 | 25 | 2017 |
Embryonic template-based generation and purification of pluripotent stem cell-derived cardiomyocytes for heart repair P Dierickx, PA Doevendans, N Geijsen, LW van Laake Journal of cardiovascular translational research 5, 566-580, 2012 | 24 | 2012 |
Circadian rhythms in stem cell biology and function P Dierickx, B Du Pré, DAM Feyen, N Geijsen, T van Veen, ... Stem cells and cardiac regeneration, 57-78, 2016 | 16 | 2016 |
Nicotinamide Riboside Improves Cardiac Function and Prolongs Survival After Disruption of the Cardiomyocyte Clock. Front P Dierickx, BJ Carpenter, I Celwyn, DP Kelly, JA Baur, MA Lazar Frontiers in Molecular Medicine 2, 887733, 2022 | 8 | 2022 |
Cardiac circadian rhythms in time and space: the future is in 4D N Chirico, LW Van Laake, JPG Sluijter, A van Mil, P Dierickx Current Opinion in Pharmacology 57, 49-59, 2021 | 8 | 2021 |
Novel roles for the transcriptional repressor E4BP4 in both cardiac physiology and pathophysiology S Mia, R Sonkar, L Williams, MN Latimer, DR Rawnsley, S Rana, J He, ... JACC: Basic to Translational Science, 2023 | 7 | 2023 |
Cardiomyocyte-specific disruption of the circadian BMAL1–REV-ERBα/β regulatory network impacts distinct miRNA species in the murine heart MN Latimer, LJ Williams, G Shanmugan, BJ Carpenter, MA Lazar, ... Communications Biology 6 (1), 1149, 2023 | 5 | 2023 |