Sachith Mettananda

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PremawardhenaProfessor in Medicine University of KelaniyaVerified email at kln.ac.lk
douglas R higgsProfessor of haematology, University of OxfordVerified email at imm.ox.ac.uk
Shaman RajindrajithProfessor of Paediatrics, University of ColomboVerified email at pdt.cmb.ac.lk
Niranga Manjuri DevanarayanaProfessor of Physiology, Faculty of Medicine, University of KelaniyaVerified email at kln.ac.lk
Richard GibbonsUniversity of OxfordVerified email at imm.ox.ac.uk
Chamila MettanandaUniversity of Kelaniya and University of OxfordVerified email at kln.ac.lk
J.W.Nirmani YasaraPhD in Molecular Medicine, Faculty of Medicine, University of KelaniyaVerified email at kln.ac.lk
Mohsin BadatUniversity of OxfordVerified email at new.ox.ac.uk
Professor Nancy OlivieriUniversity of TorontoVerified email at hemoglobal.org
Tharindi SuriapperumaDepartment of Paediatrics, Faculty of Medicine, University of KelaniyaVerified email at kln.ac.lk
Aresha ManamperiUniversity of KelaniyaVerified email at kln.ac.lk
Jim Raymond HughesUniversity of OxfordVerified email at imm.ox.ac.uk
Priyantha PereraSenior Lecturer Grade I, Department of Paediatrics, Faculty of Medicine, University of KelaniyaVerified email at kln.ac.lk
Meranthi FernandoSenior lecturer, Department of Paediatrics, Faculty of Medicine, University of Kelaniya, Sri LankaVerified email at kln.ac.lk
David C ReesKing's College Hospital and King's College LondonVerified email at kcl.ac.uk
Stephen TaylorHead of Integrative Computational Biology, Wellcome Centre for Human Genetics, Oxford UniversityVerified email at well.ox.ac.uk
Visvalingam ArunathMBBS,DCH,MD(Paed)Verified email at pgim.cmb.ac.lk
Thabitha Jebaseeli HooleTrainee in Paediatric EndocrinologyVerified email at pgim.cmb.ac.lk
Benny Kai Guo LooKK Women's and Children's HospitalVerified email at singhealth.com.sg
Professor Randula RanawakaConsultant Paediatric Nephrologist, Lady Ridgeway Hospital for Children & University of Colombo.Verified email at pdt.cmb.ac.lk

Sachith Mettananda

University of Kelaniya & Colombo North Teaching Hospital, Sri Lanka and University of Oxford, UK

Verified email at kln.ac.lk - Homepage

Thalassaemia Paediatric red cell disorders Paediatrics


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Abdominal pain–predominant functional gastrointestinal diseases in children and adolescents: prevalence, symptomatology, and association with emotional stress NM Devanarayana, S Mettananda, C Liyanarachchi, N Nanayakkara, ... Journal of pediatric gastroenterology and nutrition 53 (6), 659-665, 2011	202	2011
α-Globin as a molecular target in the treatment of β-thalassemia S Mettananda, RJ Gibbons, DR Higgs Blood, The Journal of the American Society of Hematology 125 (24), 3694-3701, 2015	167	2015
Molecular basis and genetic modifiers of thalassemia S Mettananda, DR Higgs Hematology/Oncology Clinics 32 (2), 177-191, 2018	150	2018
Editing an α-globin enhancer in primary human hematopoietic stem cells as a treatment for β-thalassemia S Mettananda, CA Fisher, D Hay, M Badat, L Quek, K Clark, P Hublitz, ... Nature communications 8 (1), 424, 2017	122*	2017
Analysis of effects of meteorological factors on dengue incidence in Sri Lanka using time series data K Goto, B Kumarendran, S Mettananda, D Gunasekara, Y Fujii, S Kaneko PloS one 8 (5), e63717, 2013	95	2013
Understanding α‐globin gene regulation and implications for the treatment of β‐thalassemia S Mettananda, RJ Gibbons, DR Higgs Annals of the New York Academy of Sciences 1368 (1), 16-24, 2016	53	2016
Significant Benefits of AIP Testing and Clinical Screening in Familial Isolated and Young-onset Pituitary Tumors P Marques, F Caimari, LC Hernández-Ramírez, D Collier, D Iacovazzo, ... The Journal of Clinical Endocrinology & Metabolism 105 (6), e2247-e2260, 2020	49	2020
Health related quality of life among children with transfusion dependent β-thalassaemia major and haemoglobin E β-thalassaemia in Sri Lanka: a case control study S Mettananda, H Pathiraja, R Peiris, D Bandara, U de Silva, ... Health and quality of life outcomes 17, 1-13, 2019	45	2019
Global burden of cardiovascular diseases and risks, 1990-2022 GA Mensah, V Fuster, CJL Murray, GA Roth, ... Journal of the American College of Cardiology 82 (25), 2350-2473, 2023	44	2023
Selective silencing of α-globin by the histone demethylase inhibitor IOX1: a potentially new pathway for treatment of β-thalassemia S Mettananda, CA Fisher, JA Sloane-Stanley, S Taylor, U Oppermann, ... Haematologica 102 (3), e80, 2017	42	2017
Human induced pluripotent stem cell derived erythroblasts can undergo definitive erythropoiesis and co‐express gamma and beta globins CT Yang, A French, PA Goh, A Pagnamenta, S Mettananda, J Taylor, ... British journal of haematology 166 (3), 435-448, 2014	41	2014
A nationwide survey of hospital-based thalassemia patients and standards of care and a preliminary assessment of the national prevention program in Sri Lanka AP Premawardhana, R Mudiyanse, ST De Silva, N Jiffry, U Nelumdeniya, ... PloS one 14 (8), e0220852, 2019	34	2019
Blood transfusion therapy for β‐thalassemia major and hemoglobin E β‐thalassemia: Adequacy, trends, and determinants in Sri Lanka S Mettananda, H Pathiraja, R Peiris, N Wickramarathne, D Bandara, ... Pediatric blood & cancer 66 (5), e27643, 2019	32	2019
Anaemia among females in child-bearing age: relative contributions, effects and interactions of α-and β-thalassaemia S Mettananda, M Suranjan, R Fernando, T Dias, C Mettananda, ... PloS one 13 (11), e0206928, 2018	32	2018
Synergistic silencing of α-globin and induction of γ-globin by histone deacetylase inhibitor, vorinostat as a potential therapy for β-thalassaemia S Mettananda, N Yasara, CA Fisher, S Taylor, R Gibbons, D Higgs Scientific reports 9 (1), 11649, 2019	31	2019
A comprehensive review of hydroxyurea for β-haemoglobinopathies: the role revisited during COVID-19 pandemic N Yasara, A Premawardhena, S Mettananda Orphanet Journal of Rare Diseases 16, 1-12, 2021	29	2021
Management of thalassaemia S Mettananda Sri Lanka College of Paediatricians, 2018	29	2018
Constipation and functional faecal retention in a group of school children in a district in Sri Lanka S Rajindrajith, N Devanarayana, S Mettananda, P Perera, S Jasmin, ... Sri Lanka Journal of Child Health 38 (2), 2009	28	2009
Anaemia in children: are we using the correct prevention strategies? S Mettananda, DGH De Silva Sri Lanka Medical Association, 2017	26	2017
Body iron status of children and adolescents with transfusion dependent β-thalassaemia: trends of serum ferritin and associations of optimal body iron control T Suriapperuma, R Peiris, C Mettananda, A Premawardhena, ... BMC research notes 11, 1-6, 2018	24	2018

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