Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity D Boucher, M Monteleone, RC Coll, KW Chen, CM Ross, JL Teo, ... Journal of Experimental Medicine 215 (3), 827-840, 2018 | 466 | 2018 |
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation SL Masters, V Lagou, I Jéru, PJ Baker, L Van Eyck, DA Parry, D Lawless, ... Science translational medicine 8 (332), 332ra45-332ra45, 2016 | 302 | 2016 |
Interleukin-1β maturation triggers its relocation to the plasma membrane for gasdermin-D-dependent and-independent secretion M Monteleone, AC Stanley, KW Chen, DL Brown, JS Bezbradica, ... Cell reports 24 (6), 1425-1433, 2018 | 270 | 2018 |
Sulfonylureas as concomitant insulin secretagogues and NLRP3 inflammasome inhibitors JR Hill, RC Coll, N Sue, JC Reid, J Dou, CL Holley, R Pelingon, ... ChemMedChem 12 (17), 1449-1457, 2017 | 52 | 2017 |
The rOX‐stars of inflammation: links between the inflammasome and mitochondrial meltdown CL Holley, K Schroder Clinical & translational immunology 9 (2), e01109, 2020 | 37 | 2020 |
Parkinson's disease: connecting mitochondria to inflammasomes GMEP Lawrence, CL Holley, K Schroder Trends in Immunology 43 (11), 877-885, 2022 | 21 | 2022 |
Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release LI Labzin, KY Chew, K Eschke, X Wang, T Esposito, CJ Stocks, J Rae, ... Science Signaling 16 (782), eabq1366, 2023 | 15 | 2023 |
Mitochondrial DNA synthesis fuels NLRP3 activation. RC Coll, CL Holley, K Schroder Cell Research 28 (11), 1046-1047, 2018 | 14 | 2018 |
Mitochondrial DNA synthesis fuels NLRP3 inflammasome RC Coll, CL Holley, K Schroder Cell Research 28 (11), 1046-1047, 2018 | 13 | 2018 |
Come on mtDNA, light my fire GMEP Lawrence, CL Holley, K Schroder Immunity 55 (8), 1331-1333, 2022 | 6 | 2022 |
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation. Sci Transl Med 8: 332ra345 SL Masters, V Lagou, I Jeru, PJ Baker, L Van Eyck, DA Parry, D Lawless, ... | 4 | 2016 |
Isolation and culture of pure adult mouse microglia and astrocytes for in vitro characterization and analyses MT Milner, GMEP Lawrence, CL Holley, LG Bodea, J Götz, SS Burgener, ... STAR protocols 3 (2), 101295, 2022 | 3 | 2022 |
ACE2 is necessary for SARS-CoV-2 infection and sensing by macrophages but not sufficient for productive viral replication LI Labzin, KY Chew, X Wang, T Esposito, CJ Stocks, J Rae, T Yordanov, ... | 3 | 2022 |
Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and-Independent Secretion. Cell Rep 24: 1425–1433 M Monteleone, AC Stanley, KW Chen, DL Brown, JS Bezbradica, ... | 3 | 2018 |
NLRP12 interacts with NLRP3 to block the activation of the human NLRP3 inflammasome JR Coombs, A Zamoshnikova, CL Holley, MP Maddugoda, DET Teo, ... Science Signaling 17 (820), eabg8145, 2024 | 1 | 2024 |
Macrophages only sense infectious SARS-CoV-2 when they express sufficient ACE2 to permit viral entry, where rapid cytokine responses then limit viral replication LI Labzin, KY Chew, K Eschke, X Wang, T Esposito, CJ Stocks, J Rae, ... bioRxiv, 2022.03. 22.485248, 2022 | 1 | 2022 |
Nlrc3 restrains responses to a T CL Holley, RC Coll, K Schroder Immunity 49 (6), 989-991, 2018 | 1 | 2018 |
Author Correction: Mitochondrial DNA synthesis fuels NLRP3 inflammasome RC Coll, CL Holley, K Schroder Cell Research 28 (12), 1202, 2018 | 1 | 2018 |
Live Imaging of Pyroptosis in Primary Murine Macrophages CL Holley, K Schroder Inflammation and Cancer: Methods and Protocols, 139-153, 2023 | | 2023 |
ACE2 is necessary for SARS-CoV-2 infection and sensing by macrophages but not sufficient for productive viral replication (preprint) LI Labzin, KY Chew, X Wang, T Esposito, CJ Stocks, J Rae, T Yordanov, ... | | 2022 |