Novel alanine serine cysteine transporter 2 (ASCT2) inhibitors based on sulfonamide and sulfonic acid ester scaffolds E Ndaru, RAA Garibsingh, YY Shi, E Wallace, P Zakrepine, J Wang, ... Journal of General Physiology 151 (3), 357-368, 2019 | 34 | 2019 |
Energy landscape of the substrate translocation equilibrium of plasma-membrane glutamate transporters J Wang, T Albers, C Grewer The Journal of Physical Chemistry B 122 (1), 28-39, 2018 | 21 | 2018 |
Mechanism and potential sites of potassium interaction with glutamate transporters J Wang, K Zhang, P Goyal, C Grewer Journal of General Physiology 152 (10), 2020 | 16 | 2020 |
Transient kinetics reveal mechanism and voltage dependence of inhibitor and substrate binding to glutamate transporters L Zielewicz, J Wang, E Ndaru, CT Grewer ACS Chemical Biology 14 (5), 1002-1010, 2019 | 13 | 2019 |
Conserved allosteric inhibition mechanism in SLC1 transporters Y Dong, J Wang, RA Garibsingh, K Hutchinson, Y Shi, G Eisenberg, X Yu, ... Elife 12, e83464, 2023 | 11 | 2023 |
Structures and gating mechanisms of human bestrophin anion channels AP Owji, J Wang, A Kittredge, Z Clark, Y Zhang, WA Hendrickson, T Yang Nature communications 13 (1), 3836, 2022 | 11 | 2022 |
A K+/Na+ co-binding state: Simultaneous versus competitive binding of K+ and Na+ to glutamate transporters J Wang, L Zielewicz, C Grewer Journal of Biological Chemistry 294 (32), 12180-12190, 2019 | 10 | 2019 |
Observing spontaneous, accelerated substrate binding in molecular dynamics simulations of glutamate transporters J Wang, P Li, X Yu, C Grewer Plos one 16 (4), e0250635, 2021 | 8 | 2021 |
Pre-steady-state kinetics and reverse transport in rat glutamate transporter EAAC1 with an immobilized transport domain J Wang, L Zielewicz, Y Dong, C Grewer Neurochemical research, 1-15, 2021 | 8 | 2021 |
Pre-Steady-State Kinetic Analysis of Amino Acid Transporter SLC6A14 Reveals Rapid Turnover Rate and Substrate Translocation Y Shi, J Wang, EK Ndaru, C Grewer Frontiers in Physiology, 1965, 2021 | 7 | 2021 |
Bestrophin-2 and glutamine synthetase form a complex for glutamate release AP Owji, K Yu, A Kittredge, J Wang, Y Zhang, T Yang Nature 611 (7934), 180-187, 2022 | 4 | 2022 |
Functional and kinetic comparison of alanine cysteine serine transporters ASCT1 and ASCT2 J Wang, Y Dong, C Grewer Biomolecules 12 (1), 113, 2022 | 4 | 2022 |
A pathogenic in-frame deletion-insertion variant in BEST1 phenocopies Stargardt disease M Kolesnikova, JK Oh, J Wang, W Lee, J Zernant, PY Su, AH Kim, ... JCI insight 7 (23), 2022 | 2 | 2022 |
Design and Characterization of Prodrug-like Inhibitors for Preventing Glutamate Efflux through Reverse Transport LJ Zielewicz, J Wang, E Ndaru, B Maney, X Yu, T Albers, C Grewer ACS Chemical Neuroscience 14 (23), 4252-4263, 2023 | 1 | 2023 |
Conserved allosteric binding pocket in SLC1 glutamate transporter EAAT1 and neutral amino acid transporter ASCT2 Y Dong, J Wang, G Eisenberg, X Yu, A Schlessinger, CT Grewer Biophysical Journal 121 (3), 250a, 2022 | 1 | 2022 |
Bestrophin-2 and glutamine synthetase form a complex for glutamate release A Kittredge, AP Owji, K Yu, J Wang, Y Zhang, T Yang Biophysical Journal 122 (3), 113a, 2023 | | 2023 |
Structure and Functional Studies of Glutamate Transporters EAAT J Wang State University of New York at Binghamton, 2021 | | 2021 |
Mechanism and Potential Sites of Potassium Interaction with the Glutamate Transporter EAAC1 J Wang, CT Grewer Biophysical Journal 116 (3), 556a, 2019 | | 2019 |
Voltage Dependent Inhibitor Binding to Plasma-Membrane Glutamate Transporters LJ Zielewicz, J Wang, E Ndaru, CT Grewer Biophysical Journal 116 (3), 556a, 2019 | | 2019 |