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Jake Jianjun Wen
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Oxidative damage during chagasic cardiomyopathy development: role of mitochondrial oxidant release and inefficient antioxidant defense
JJ Wen, G Vyatkina, N Garg
Free Radical Biology and Medicine 37 (11), 1821-1833, 2004
1552004
Oxidative stress in Chagas disease
S Gupta, JJ Wen, NJ Garg
Interdisciplinary perspectives on infectious diseases 2009, 2009
1412009
Increased oxidative stress is correlated with mitochondrial dysfunction in chagasic patients
J Wen, PC Yachelini, A Sembaj, RE Manzur, NJ Garg
Free Radical Biology and Medicine 41 (2), 270-276, 2006
1392006
Trypanosoma cruzi infection disturbs mitochondrial membrane potential and ROS production rate in cardiomyocytes
S Gupta, V Bhatia, J Wen, Y Wu, MH Huang, NJ Garg
Free Radical Biology and Medicine 47 (10), 1414-1421, 2009
1362009
Differential gene expression in fully-grown oocytes between gynogenetic and gonochoristic crucian carps
J Xie, JJ Wen, B Chen, JF Gui
Gene 271 (1), 109-116, 2001
1192001
An overview of chagasic cardiomyopathy: pathogenic importance of oxidative stress
MA Zacks, JJ Wen, G Vyatkina, V Bhatia, N Garg
Anais da Academia Brasileira de Ciências 77, 695-715, 2005
1162005
Oxidative modification of mitochondrial respiratory complexes in response to the stress of Trypanosoma cruzi infection
JJ Wen, N Garg
Free Radical Biology and Medicine 37 (12), 2072-2081, 2004
1132004
Characterization and gene cloning of a cold-active cellulase from a deep-sea psychrotrophic bacterium Pseudoalteromonas sp. DY3
R Zeng, P Xiong, J Wen
Extremophiles 10, 79-82, 2006
1052006
Tissue-specific oxidative imbalance and mitochondrial dysfunction during Trypanosoma cruzi infection in mice
JJ Wen, M Dhiman, EB Whorton, NJ Garg
Microbes and Infection 10 (10-11), 1201-1209, 2008
982008
Phenyl-α-tert-butyl-nitrone and benzonidazole treatment controlled the mitochondrial oxidative stress and evolution of cardiomyopathy in chronic chagasic rats
JJ Wen, S Gupta, Z Guan, M Dhiman, D Condon, C Lui, NJ Garg
Journal of the American College of Cardiology 55 (22), 2499-2508, 2010
942010
SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart …
X Wan, J Wen, SJ Koo, LY Liang, NJ Garg
PLoS pathogens 12 (10), e1005954, 2016
902016
Aldose reductase inhibitor increases doxorubicin-sensitivity of colon cancer cells and decreases cardiotoxicity
H Sonowal, PB Pal, JJ Wen, S Awasthi, KV Ramana, SK Srivastava
Scientific reports 7 (1), 3182, 2017
802017
Mitochondrial generation of reactive oxygen species is enhanced at the Qo site of the complex III in the myocardium of Trypanosoma cruzi-infected mice: beneficial …
JJ Wen, NJ Garg
Journal of bioenergetics and biomembranes 40, 587-598, 2008
752008
Enhanced nitrosative stress during Trypanosoma cruzi infection causes nitrotyrosine modification of host proteins: implications in Chagas' disease
M Dhiman, ES Nakayasu, YH Madaiah, BK Reynolds, J Wen, IC Almeida, ...
The American journal of pathology 173 (3), 728-740, 2008
752008
Phenyl-α-tert-butyl nitrone reverses mitochondrial decay in acute Chagas' disease
JJ Wen, V Bhatia, VL Popov, NJ Garg
The American journal of pathology 169 (6), 1953-1964, 2006
632006
PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance
JJ Wen, YW Yin, NJ Garg
PLoS pathogens 14 (5), e1007065, 2018
612018
Mitochondrial Complex III Defects Contribute to Inefficient Respiration and ATP Synthesis in the Myocardium of Trypanosoma cruzi–Infected Mice
JJ Wen, NJ Garg
Antioxidants & redox signaling 12 (1), 27-37, 2010
532010
ROS signalling of inflammatory cytokines during Trypanosoma cruzi infection
S Gupta, M Dhiman, J Wen, NJ Garg
Advances in parasitology 76, 153-170, 2011
492011
Manganese superoxide dismutase deficiency exacerbates the mitochondrial ROS production and oxidative damage in Chagas disease
JJ Wen, NJ Garg
PLoS neglected tropical diseases 12 (7), e0006687, 2018
482018
Serum proteomic signature of human chagasic patients for the identification of novel potential protein biomarkers of disease
JJ Wen, MP Zago, S Nunez, S Gupta, FN Burgos, NJ Garg
Molecular & Cellular Proteomics 11 (8), 435-452, 2012
392012
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