| Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1β, IL-18, IL-6, and neutrophil infiltration in the kidney S Faubel, EC Lewis, L Reznikov, D Ljubanovic, TS Hoke, H Somerset, ... Journal of Pharmacology and Experimental Therapeutics 322 (1), 8-15, 2007 | 460 | 2007 |
| Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance MG Netea, LAB Joosten, E Lewis, DR Jensen, PJ Voshol, BJ Kullberg, ... Nature medicine 12 (6), 650-656, 2006 | 456 | 2006 |
| IL-1 family nomenclature C Dinarello, W Arend, J Sims, D Smith, H Blumberg, L O'Neill, ... Nature immunology 11 (11), 973-973, 2010 | 418 | 2010 |
| The histone deacetylase inhibitor ITF2357 reduces production of pro-inflammatory cytokines in vitro and systemic inflammation in vivo F Leoni, G Fossati, EC Lewis, JK Lee, G Porro, P Pagani, D Modena, ... Molecular medicine 11, 1-15, 2005 | 416 | 2005 |
| Differences in signaling pathways by IL-1β and IL-18 JK Lee, SH Kim, EC Lewis, T Azam, LL Reznikov, CA Dinarello Proceedings of the National Academy of Sciences 101 (23), 8815-8820, 2004 | 294 | 2004 |
| Anti-inflammatory and immunomodulatory properties of α1-antitrypsin without inhibition of elastase D Jonigk, M Al-Omari, L Maegel, M Müller, N Izykowski, J Hong, K Hong, ... Proceedings of the National Academy of Sciences 110 (37), 15007-15012, 2013 | 266 | 2013 |
| Mycobacterium tuberculosis induces interleukin-32 production through a caspase-1/IL-18/interferon-γ-dependent mechanism MG Netea, T Azam, EC Lewis, LAB Joosten, M Wang, D Langenberg, ... PLoS medicine 3 (8), e277, 2006 | 246 | 2006 |
| α1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice EC Lewis, M Mizrahi, M Toledano, N DeFelice, JL Wright, A Churg, ... Proceedings of the National Academy of Sciences 105 (42), 16236-16241, 2008 | 229 | 2008 |
| α1-antitrypsin monotherapy prolongs islet allograft survival in mice EC Lewis, L Shapiro, OJ Bowers, CA Dinarello Proceedings of the National Academy of Sciences 102 (34), 12153-12158, 2005 | 229 | 2005 |
| IL-37 protects against obesity-induced inflammation and insulin resistance DB Ballak, JA Van Diepen, AR Moschen, HJ Jansen, A Hijmans, ... Nature communications 5 (1), 4711, 2014 | 220 | 2014 |
| Interleukin-32 induces the differentiation of monocytes into macrophage-like cells MG Netea, EC Lewis, T Azam, LAB Joosten, J Jaekal, SY Bae, ... Proceedings of the National Academy of Sciences 105 (9), 3515-3520, 2008 | 200 | 2008 |
| Interleukin-1β regulates fat-liver crosstalk in obesity by auto-paracrine modulation of adipose tissue inflammation and expandability O Nov, H Shapiro, H Ovadia, T Tarnovscki, I Dvir, E Shemesh, J Kovsan, ... PloS one 8 (1), e53626, 2013 | 181 | 2013 |
| Expanding the Clinical Indications for α1-Antitrypsin Therapy EC Lewis Molecular medicine 18, 957-970, 2012 | 178 | 2012 |
| The unique hypusine modification of eIF5A promotes islet β cell inflammation and dysfunction in mice B Maier, T Ogihara, AP Trace, SA Tersey, RD Robbins, SK Chakrabarti, ... The Journal of clinical investigation 120 (6), 2156-2170, 2010 | 175 | 2010 |
| Alpha-1-antitrypsin monotherapy reduces graft-versus-host disease after experimental allogeneic bone marrow transplantation I Tawara, Y Sun, EC Lewis, T Toubai, R Evers, E Nieves, T Azam, ... Proceedings of the National Academy of Sciences 109 (2), 564-569, 2012 | 160 | 2012 |
| Alpha-1 antitrypsin inhibits caspase-1 and protects from acute myocardial ischemia–reperfusion injury S Toldo, IM Seropian, E Mezzaroma, BW Van Tassell, FN Salloum, ... Journal of molecular and cellular cardiology 51 (2), 244-251, 2011 | 157 | 2011 |
| The efficacy of an immunoisolating membrane system for islet xenotransplantation in minipigs T Neufeld, B Ludwig, U Barkai, GC Weir, CK Colton, Y Evron, M Balyura, ... PloS one 8 (8), e70150, 2013 | 141 | 2013 |
| Interleukin-1β may mediate insulin resistance in liver-derived cells in response to adipocyte inflammation O Nov, A Kohl, EC Lewis, N Bashan, I Dvir, S Ben-Shlomo, S Fishman, ... Endocrinology 151 (9), 4247-4256, 2010 | 138 | 2010 |
| The Oral Histone Deacetylase Inhibitor ITF2357 Reduces Cytokines and Protects Islet β Cells In Vivo and In Vitro EC Lewis, L Blaabjerg, J Størling, SG Ronn, P Mascagni, CA Dinarello, ... Molecular medicine 17, 369-377, 2011 | 124 | 2011 |
| α1-Antitrypsin infusion for treatment of steroid-resistant acute graft-versus-host disease JM Magenau, SC Goldstein, D Peltier, RJ Soiffer, T Braun, A Pawarode, ... Blood, The Journal of the American Society of Hematology 131 (12), 1372-1379, 2018 | 98 | 2018 |
