| Characterization of sleep in zebrafish and insomnia in hypocretin receptor mutants T Yokogawa, W Marin, J Faraco, G Pézeron, L Appelbaum, J Zhang, ... PLoS biology 5 (10), e277, 2007 | 395 | 2007 |
| Light-responsive cryptochromes from a simple multicellular animal, the coral Acropora millepora O Levy, L Appelbaum, W Leggat, Y Gothlif, DC Hayward, DJ Miller, ... Science 318 (5849), 467-470, 2007 | 306 | 2007 |
| Synaptic plasticity in sleep: learning, homeostasis and disease G Wang, B Grone, D Colas, L Appelbaum, P Mourrain Trends in neurosciences 34 (9), 452-463, 2011 | 209 | 2011 |
| Neuronal mechanisms for sleep/wake regulation and modulatory drive A Eban-Rothschild, L Appelbaum, L de Lecea Neuropsychopharmacology 43 (5), 937-952, 2018 | 206 | 2018 |
| Sleep–wake regulation and hypocretin–melatonin interaction in zebrafish L Appelbaum, GX Wang, GS Maro, R Mori, A Tovin, W Marin, T Yokogawa, ... Proceedings of the National Academy of Sciences 106 (51), 21942-21947, 2009 | 188 | 2009 |
| Circadian and homeostatic regulation of structural synaptic plasticity in hypocretin neurons L Appelbaum, G Wang, T Yokogawa, GM Skariah, SJ Smith, P Mourrain, ... Neuron 68 (1), 87-98, 2010 | 182 | 2010 |
| Light directs zebrafish period2 expression via conserved D and E boxes G Vatine, D Vallone, L Appelbaum, P Mracek, Z Ben-Moshe, K Lahiri, ... PLoS biology 7 (10), e1000223, 2009 | 152 | 2009 |
| Sleep increases chromosome dynamics to enable reduction of accumulating DNA damage in single neurons D Zada, I Bronshtein, T Lerer-Goldshtein, Y Garini, L Appelbaum Nature communications 10 (1), 895, 2019 | 130 | 2019 |
| Regulation of hypocretin (orexin) expression in embryonic zebrafish JH Faraco, L Appelbaum, W Marin, SE Gaus, P Mourrain, E Mignot Journal of Biological Chemistry 281 (40), 29753-29761, 2006 | 128 | 2006 |
| Genetic ablation of hypocretin neurons alters behavioral state transitions in zebrafish I Elbaz, L Yelin-Bekerman, J Nicenboim, G Vatine, L Appelbaum Journal of Neuroscience 32 (37), 12961-12972, 2012 | 107 | 2012 |
| Circadian clocks, rhythmic synaptic plasticity and the sleep-wake cycle in zebrafish I Elbaz, NS Foulkes, Y Gothilf, L Appelbaum Frontiers in neural circuits 7, 9, 2013 | 97 | 2013 |
| Altered behavioral performance and live imaging of circuit-specific neural deficiencies in a zebrafish model for psychomotor retardation D Zada, A Tovin, T Lerer-Goldshtein, GD Vatine, L Appelbaum PLoS genetics 10 (9), e1004615, 2014 | 91 | 2014 |
| Fmrp interacts with adar and regulates RNA editing, synaptic density and locomotor activity in zebrafish A Shamay-Ramot, K Khermesh, HT Porath, M Barak, Y Pinto, C Wachtel, ... PLoS genetics 11 (12), e1005702, 2015 | 84 | 2015 |
| Zebrafish as a model for monocarboxyl transporter 8-deficiency GD Vatine, D Zada, T Lerer-Goldshtein, A Tovin, G Malkinson, K Yaniv, ... Journal of Biological Chemistry 288 (1), 169-180, 2013 | 76 | 2013 |
| Zebrafish arylalkylamine-N-acetyltransferase genes–targets for regulation of the circadian clock L Appelbaum, D Vallone, A Anzulovich, L Ziv, M Tom, NS Foulkes, ... Journal of molecular endocrinology 36 (2), 337-347, 2006 | 69 | 2006 |
| Comparative expression of p2x receptors and ecto-nucleoside triphosphate diphosphohydrolase 3 in hypocretin and sensory neurons in zebrafish L Appelbaum, G Skariah, P Mourrain, E Mignot Brain research 1174, 66-75, 2007 | 65 | 2007 |
| Homeobox-clock protein interaction in zebrafish: a shared mechanism for pineal-specific and circadian gene expression L Appelbaum, A Anzulovich, R Baler, Y Gothilf Journal of Biological Chemistry 280 (12), 11544-11551, 2005 | 61 | 2005 |
| Pharmacological treatment and BBB-targeted genetic therapy for MCT8-dependent hypomyelination in zebrafish D Zada, A Tovin, T Lerer-Goldshtein, L Appelbaum Disease models & mechanisms 9 (11), 1339-1348, 2016 | 55 | 2016 |
| Parp1 promotes sleep, which enhances DNA repair in neurons D Zada, Y Sela, N Matosevich, A Monsonego, T Lerer-Goldshtein, Y Nir, ... Molecular cell 81 (24), 4979-4993. e7, 2021 | 54 | 2021 |
| Hypocretin neuron-specific transcriptome profiling identifies the sleep modulator Kcnh4a L Yelin-Bekerman, I Elbaz, A Diber, D Dahary, L Gibbs-Bar, S Alon, ... Elife 4, e08638, 2015 | 53 | 2015 |
