Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics S Bergmann, SE Lawler, Y Qu, CM Fadzen, JM Wolfe, MS Regan, ... Nature protocols 13 (12), 2827-2843, 2018 | 210 | 2018 |
Rapid MALDI mass spectrometry imaging for surgical pathology SS Basu, MS Regan, EC Randall, WM Abdelmoula, AR Clark, ... NPJ precision oncology 3 (1), 17, 2019 | 74 | 2019 |
Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma EC Randall, KB Emdal, JK Laramy, M Kim, A Roos, D Calligaris, ... Nature communications 9 (1), 4904, 2018 | 74 | 2018 |
Localized metabolomic gradients in patient-derived xenograft models of glioblastoma EC Randall, BGC Lopez, S Peng, MS Regan, WM Abdelmoula, SS Basu, ... Cancer research 80 (6), 1258-1267, 2020 | 68 | 2020 |
Rapid discrimination of pediatric brain tumors by mass spectrometry imaging AR Clark, D Calligaris, MS Regan, D Pomeranz Krummel, JN Agar, ... Journal of Neuro-oncology 140, 269-279, 2018 | 58 | 2018 |
Automatic 3D nonlinear registration of mass spectrometry imaging and magnetic resonance imaging data WM Abdelmoula, MS Regan, BGC Lopez, EC Randall, S Lawler, ... Analytical chemistry 91 (9), 6206-6216, 2019 | 55 | 2019 |
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma DD Shi, MR Savani, MM Levitt, AC Wang, JE Endress, CE Bird, J Buehler, ... Cancer cell 40 (9), 939-956. e16, 2022 | 49 | 2022 |
Heterogeneous delivery across the blood-brain barrier limits the efficacy of an EGFR-targeting antibody drug conjugate in glioblastoma BM Marin, KA Porath, S Jain, M Kim, JE Conage-Pough, JH Oh, CL Miller, ... Neuro-oncology 23 (12), 2042-2053, 2021 | 40 | 2021 |
A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma S Pal, JP Kaplan, H Nguyen, SA Stopka, MR Savani, MS Regan, ... Cancer Cell 40 (9), 957-972. e10, 2022 | 32 | 2022 |
Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways S Venneti, AR Kawakibi, S Ji, SM Waszak, SR Sweha, M Mota, M Pun, ... Cancer discovery 13 (11), 2370-2393, 2023 | 28 | 2023 |
Single cell spatial analysis reveals the topology of immunomodulatory purinergic signaling in glioblastoma S Coy, S Wang, SA Stopka, JR Lin, C Yapp, CC Ritch, L Salhi, GJ Baker, ... Nature communications 13 (1), 4814, 2022 | 27 | 2022 |
BAF complex maintains glioma stem cells in pediatric H3K27M glioma E Panditharatna, JG Marques, T Wang, MC Trissal, I Liu, L Jiang, A Beck, ... Cancer discovery 12 (12), 2880-2905, 2022 | 25 | 2022 |
Chronic convection-enhanced delivery of topotecan for patients with recurrent glioblastoma: a first-in-patient, single-centre, single-arm, phase 1b trial EF Spinazzi, MG Argenziano, PS Upadhyayula, MA Banu, JA Neira, ... The Lancet Oncology 23 (11), 1409-1418, 2022 | 25 | 2022 |
A unique subset of glycolytic tumour-propagating cells drives squamous cell carcinoma JE Choi, C Sebastian, CM Ferrer, CA Lewis, M Sade-Feldman, T LaSalle, ... Nature metabolism 3 (2), 182-195, 2021 | 23 | 2021 |
In vitro liquid extraction surface analysis mass spectrometry (ivLESA-MS) for direct metabolic analysis of adherent cells in culture SS Basu, EC Randall, MS Regan, BGC Lopez, AR Clark, ND Schmitt, ... Analytical chemistry 90 (8), 4987-4991, 2018 | 23 | 2018 |
β-cyclodextrin-poly (β-amino ester) nanoparticles are a generalizable strategy for high loading and sustained release of HDAC inhibitors S Chaudhuri, MJ Fowler, C Baker, SA Stopka, MS Regan, L Sablatura, ... ACS applied materials & interfaces 13 (18), 20960-20973, 2021 | 18 | 2021 |
Metal oxide laser ionization mass spectrometry imaging (MOLI MSI) using cerium (IV) oxide SS Basu, MH McMinn, B Giménez-Cassina Lopéz, MS Regan, ... Analytical chemistry 91 (10), 6800-6807, 2019 | 17 | 2019 |
PARP-inhibition reprograms macrophages toward an anti-tumor phenotype L Wang, D Wang, O Sonzogni, S Ke, Q Wang, A Thavamani, F Batalini, ... Cell reports 41 (2), 2022 | 16 | 2022 |
massNet: integrated processing and classification of spatially resolved mass spectrometry data using deep learning for rapid tumor delineation WM Abdelmoula, SA Stopka, EC Randall, M Regan, JN Agar, JN Sarkaria, ... Bioinformatics 38 (7), 2015-2021, 2022 | 14 | 2022 |
Interim clinical trial analysis of intraoperative mass spectrometry for breast cancer surgery SS Basu, SA Stopka, WM Abdelmoula, EC Randall, ... NPJ Breast Cancer 7 (1), 116, 2021 | 14 | 2021 |