Fluoro-ketopyranosyl nucleosides: Synthesis and biological evaluation of 3-fluoro-2-keto-β-D-glucopyranosyl derivatives of N4-benzoyl cytosine S Manta, G Agelis, T Botić, A Cencič, D Komiotis Bioorganic & medicinal chemistry 15 (2), 980-987, 2007 | 73 | 2007 |
1-(3-Deoxy-3-fluoro-β-D-glucopyranosyl) pyrimidine derivatives as inhibitors of glycogen phosphorylase b: Kinetic, crystallographic and modelling studies VG Tsirkone, E Tsoukala, C Lamprakis, S Manta, JM Hayes, VT Skamnaki, ... Bioorganic & medicinal chemistry 18 (10), 3413-3425, 2010 | 69 | 2010 |
The σ‐Hole Phenomenon of Halogen Atoms Forms the Structural Basis of the Strong Inhibitory Potency of C5 Halogen Substituted Glucopyranosyl Nucleosides towards Glycogen … AL Kantsadi, JM Hayes, S Manta, VT Skamnaki, C Kiritsis, AMG Psarra, ... ChemMedChem 7 (4), 722-732, 2012 | 62 | 2012 |
Competitive inhibition of human poly (A)-specific ribonuclease (PARN) by synthetic fluoro-pyranosyl nucleosides NAA Balatsos, D Vlachakis, P Maragozidis, S Manta, D Anastasakis, ... Biochemistry 48 (26), 6044-6051, 2009 | 58 | 2009 |
Unsaturated fluoro-ketopyranosyl nucleosides: Synthesis and biological evaluation of 3-fluoro-4-keto-β-D-glucopyranosyl derivatives of N4-benzoyl cytosine and N6-benzoyl adenine S Manta, G Agelis, T Botić, A Cencič, D Komiotis European journal of medicinal chemistry 43 (2), 420-428, 2008 | 56 | 2008 |
Dissipation, metabolism and sorption of pesticides used in fruit-packaging plants: towards an optimized depuration of their pesticide-contaminated agro-industrial effluents P Karas, A Metsoviti, V Zisis, C Ehaliotis, M Omirou, ES Papadopoulou, ... Science of the Total Environment 530, 129-139, 2015 | 51 | 2015 |
Antiviral unsaturated nucleosides D Komiotis, S Manta, E Tsoukala, N Tzioumaki Anti-Infective Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2008 | 46 | 2008 |
Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation V Parmenopoulou, DSM Chatzileontiadou, S Manta, S Bougiatioti, ... Bioorganic & medicinal chemistry 20 (24), 7184-7193, 2012 | 43 | 2012 |
Antioxidant Activity of a Series of Fluorinated Pyrano-nucleoside Analogues of N4-benzoyl Cytosine and N6-benzoyl Adenine C Spanou, S Manta, D Komiotis, A Dervishi, D Kouretas International Journal of Molecular Sciences 8 (7), 695-704, 2007 | 41 | 2007 |
Dideoxy fluoro-ketopyranosyl nucleosides as potent antiviral agents: Synthesis and biological evaluation of 2, 3-and 3, 4-dideoxy-3-fluoro-4-and-2-keto-β-d-glucopyranosyl … S Manta, E Tsoukala, N Tzioumaki, A Goropevšek, RT Pamulapati, ... European journal of medicinal chemistry 44 (6), 2696-2704, 2009 | 38 | 2009 |
Study of the interaction among Notch pathway receptors, correlation with stemness, as well as their interaction with CD44, dipeptidyl peptidase-IV, hepatocyte growth factor … P Apostolou, M Toloudi, E Ioannou, E Kourtidou, M Chatziioannou, ... Journal of Receptors and Signal Transduction 33 (6), 353-358, 2013 | 33 | 2013 |
3′‐Axial CH2OH Substitution on Glucopyranose does not Increase Glycogen Phosphorylase Inhibitory Potency. QM/MM‐PBSA Calculations Suggest Why S Manta, A Xipnitou, C Kiritsis, AL Kantsadi, JM Hayes, VT Skamnaki, ... Chemical biology & drug design 79 (5), 663-673, 2012 | 33 | 2012 |
Structure based inhibitor design targeting glycogen phosphorylase b. Virtual screening, synthesis, biochemical and biological assessment of novel N-acyl-β-d-glucopyranosylamines V Parmenopoulou, AL Kantsadi, VG Tsirkone, DSM Chatzileontiadou, ... Bioorganic & medicinal chemistry 22 (17), 4810-4825, 2014 | 31 | 2014 |
Synthesis and biological evaluation of unsaturated keto and exomethylene D-arabinopyranonucleoside analogs: Novel 5-fluorouracil analogs that target thymidylate synthase N Tzioumaki, S Manta, E Tsoukala, VV Johan, S Liekens, D Komiotis, ... European journal of medicinal chemistry 46 (4), 993-1005, 2011 | 29 | 2011 |
Unsaturated dideoxy fluoro-ketopyranosyl nucleosides as new cytostatic agents: a convenient synthesis of 2, 6-dideoxy-3-fluoro-4-keto-β-D-glucopyranosyl analogues of uracil, 5 … S Manta, N Tzioumaki, E Tsoukala, A Panagiotopoulou, M Pelecanou, ... European journal of medicinal chemistry 44 (11), 4764-4771, 2009 | 29 | 2009 |
The binding of C5-alkynyl and alkylfurano [2, 3-d] pyrimidine glucopyranonucleosides to glycogen phosphorylase b: synthesis, biochemical and biological assessment AL Kantsadi, S Manta, AMG Psarra, A Dimopoulou, C Kiritsis, ... European journal of medicinal chemistry 54, 740-749, 2012 | 27 | 2012 |
Synthesis of 4, 6-dideoxy-3-fluoro-2-keto-β-D-glucopyranosyl analogues of 5-fluorouracil, N6-benzoyl adenine, uracil, thymine, N4-benzoyl cytosine and evaluation of their … S Manta, E Tsoukala, N Tzioumaki, C Kiritsis, J Balzarini, D Komiotis Bioorganic chemistry 38 (2), 48-55, 2010 | 24 | 2010 |
Rapid microwave-enhanced synthesis of C5-alkynyl pyranonucleosides as novel cytotoxic antitumor agents A Dimopoulou, S Manta, C Kiritsis, DN Gkaragkouni, I Papasotiriou, ... Bioorganic & medicinal chemistry letters 23 (5), 1330-1333, 2013 | 22 | 2013 |
Kinetic and in silico analysis of the slow-binding inhibition of human poly (A)-specific ribonuclease (PARN) by novel nucleoside analogues N Balatsos, D Vlachakis, V Chatzigeorgiou, S Manta, D Komiotis, M Vlassi, ... Biochimie 94 (1), 214-221, 2012 | 21 | 2012 |
Branched-chain C-cyano pyranonucleosides: Synthesis of 3′-C-cyano & 3′-C-cyano-3′-deoxy pyrimidine pyranonucleosides as novel cytotoxic agents C Kiritsis, S Manta, V Parmenopoulou, J Balzarini, D Komiotis European journal of medicinal chemistry 46 (11), 5668-5674, 2011 | 21 | 2011 |