The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis C Crewe, YA An, PE Scherer The Journal of clinical investigation 127 (1), 74-82, 2017 | 634 | 2017 |
An endothelial-to-adipocyte extracellular vesicle axis governed by metabolic state C Crewe, N Joffin, JM Rutkowski, M Kim, F Zhang, DA Towler, R Gordillo, ... Cell 175 (3), 695-708. e13, 2018 | 316 | 2018 |
Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes C Crewe, JB Funcke, S Li, N Joffin, CM Gliniak, AL Ghaben, YA An, ... Cell metabolism 33 (9), 1853-1868. e11, 2021 | 209 | 2021 |
Dermal adipose tissue has high plasticity and undergoes reversible dedifferentiation in mice Z Zhang, M Shao, C Hepler, Z Zi, S Zhao, YA An, Y Zhu, AL Ghaben, ... The Journal of clinical investigation 129 (12), 5327-5342, 2019 | 142 | 2019 |
Redox regulation of insulin sensitivity due to enhanced fatty acid utilization in the mitochondria PM Rindler, CL Crewe, J Fernandes, M Kinter, LI Szweda American Journal of Physiology-Heart and Circulatory Physiology 305 (5 …, 2013 | 64 | 2013 |
Rapid inhibition of pyruvate dehydrogenase: an initiating event in high dietary fat-induced loss of metabolic flexibility in the heart C Crewe, M Kinter, LI Szweda PloS one 8 (10), e77280, 2013 | 61 | 2013 |
Human endotrophin as a driver of malignant tumor growth D Bu, C Crewe, CM Kusminski, R Gordillo, AL Ghaben, M Kim, J Park, ... JCI insight 4 (9), 2019 | 59 | 2019 |
Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity Z Zhang, JB Funcke, Z Zi, S Zhao, LG Straub, Y Zhu, Q Zhu, C Crewe, ... Cell metabolism 33 (8), 1624-1639. e9, 2021 | 57 | 2021 |
Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood N Borcherding, W Jia, R Giwa, RL Field, JR Moley, BJ Kopecky, MM Chan, ... Cell metabolism 34 (10), 1499-1513. e8, 2022 | 54 | 2022 |
SREBP-regulated adipocyte lipogenesis is dependent on substrate availability and redox modulation of mTORC1 C Crewe, Y Zhu, VA Paschoal, N Joffin, AL Ghaben, R Gordillo, G Liang, ... JCI insight 4 (15), 2019 | 50 | 2019 |
Regulation of pyruvate dehydrogenase kinase 4 in the heart through degradation by the Lon protease in response to mitochondrial substrate availability C Crewe, C Schafer, I Lee, M Kinter, LI Szweda Journal of Biological Chemistry 292 (1), 305-312, 2017 | 50 | 2017 |
A novel model of diabetic complications: adipocyte mitochondrial dysfunction triggers massive β-cell hyperplasia CM Kusminski, AL Ghaben, TS Morley, RJ Samms, AC Adams, Y An, ... Diabetes 69 (3), 313-330, 2020 | 45 | 2020 |
Dysregulation of amyloid precursor protein impairs adipose tissue mitochondrial function and promotes obesity YA An, C Crewe, IW Asterholm, K Sun, S Chen, F Zhang, M Shao, ... Nature metabolism 1 (12), 1243-1257, 2019 | 44 | 2019 |
Mitochondrial metabolism is a key regulator of the fibro-inflammatory and adipogenic stromal subpopulations in white adipose tissue N Joffin, VA Paschoal, CM Gliniak, C Crewe, A Elnwasany, LI Szweda, ... Cell Stem Cell 28 (4), 702-717. e8, 2021 | 41 | 2021 |
Hyaluronan in adipose tissue: Beyond dermal filler and therapeutic carrier Y Zhu, C Crewe, PE Scherer Science translational medicine 8 (323), 323ps4-323ps4, 2016 | 41 | 2016 |
Intercellular and interorgan crosstalk through adipocyte extracellular vesicles C Crewe, PE Scherer Reviews in Endocrine and Metabolic Disorders 23 (1), 61-69, 2022 | 36 | 2022 |
Adipocyte mesenchymal transition contributes to mammary tumor progression Q Zhu, Y Zhu, C Hepler, Q Zhang, J Park, C Gliniak, GH Henry, C Crewe, ... Cell reports 40 (11), 2022 | 32 | 2022 |
Adipose tissue hyaluronan production improves systemic glucose homeostasis and primes adipocytes for CL 316,243-stimulated lipolysis Y Zhu, N Li, M Huang, M Bartels, S Dogné, S Zhao, X Chen, C Crewe, ... Nature communications 12 (1), 4829, 2021 | 22 | 2021 |
Characterization of ALTO-encoding circular RNAs expressed by Merkel cell polyomavirus and trichodysplasia spinulosa polyomavirus R Yang, EE Lee, J Kim, JH Choi, E Kolitz, Y Chen, C Crewe, ... PLoS pathogens 17 (5), e1009582, 2021 | 22 | 2021 |
Adipose tissue macrophages exert systemic metabolic control by manipulating local iron concentrations N Joffin, CM Gliniak, JB Funcke, VA Paschoal, C Crewe, S Chen, ... Nature Metabolism 4 (11), 1474-1494, 2022 | 20 | 2022 |