| Prolonged diabetes reversal after intraportal xenotransplantation of wild-type porcine islets in immunosuppressed nonhuman primates BJ Hering, M Wijkstrom, ML Graham, M Hårdstedt, TC Aasheim, T Jie, ... Nature medicine 12 (3), 301-303, 2006 | 627 | 2006 |
| The streptozotocin-induced diabetic nude mouse model: differences between animals from different sources ML Graham, JL Janecek, JA Kittredge, BJ Hering, HJ Schuurman Comparative medicine 61 (4), 356-360, 2011 | 376 | 2011 |
| The multifactorial role of the 3Rs in shifting the harm-benefit analysis in animal models of disease ML Graham, MJ Prescott European Journal of Pharmacology 759, 19-29, 2015 | 200 | 2015 |
| A completely biological “off-the-shelf” arteriovenous graft that recellularizes in baboons ZH Syedain, ML Graham, TB Dunn, T O’Brien, SL Johnson, ... Science translational medicine 9 (414), eaan4209, 2017 | 137 | 2017 |
| Extrahepatic islet transplantation with microporous polymer scaffolds in syngeneic mouse and allogeneic porcine models RF Gibly, X Zhang, ML Graham, BJ Hering, DB Kaufman, WL Lowe Jr, ... Biomaterials 32 (36), 9677-9684, 2011 | 100 | 2011 |
| Species incompatibilities in the pig‐to‐macaque islet xenotransplant model affect transplant outcome: a comparison with allotransplantation ML Graham, MD Bellin, KK Papas, BJ Hering, HJ Schuurman Xenotransplantation 18 (6), 328-342, 2011 | 82 | 2011 |
| Report of the key opinion leaders meeting on stem cell-derived beta cells J Odorico, J Markmann, D Melton, J Greenstein, A Hwa, C Nostro, ... Transplantation 102 (8), 1223-1229, 2018 | 78 | 2018 |
| Successful implementation of cooperative handling eliminates the need for restraint in a complex non‐human primate disease model ML Graham, EF Rieke, LA Mutch, EK Zolondek, AW Faig, TA DuFour, ... Journal of medical primatology 41 (2), 89-106, 2012 | 74 | 2012 |
| Validity of animal models of type 1 diabetes, and strategies to enhance their utility in translational research ML Graham, HJ Schuurman European journal of pharmacology 759, 221-230, 2015 | 68 | 2015 |
| Differences in glucose‐stimulated insulin secretion in vitro of islets from human, nonhuman primate, and porcine origin KR Mueller, AN Balamurugan, GW Cline, RL Pongratz, RL Hooper, ... Xenotransplantation 20 (2), 75-81, 2013 | 68 | 2013 |
| The safety, efficacy and regulatory triangle in drug development: Impact for animal models and the use of animals PJK Van Meer, ML Graham, HJ Schuurman European journal of pharmacology 759, 3-13, 2015 | 54 | 2015 |
| Long-term tolerance of islet allografts in nonhuman primates induced by apoptotic donor leukocytes A Singh, S Ramachandran, ML Graham, S Daneshmandi, D Heller, ... Nature communications 10 (1), 1-16, 2019 | 52 | 2019 |
| A comprehensive microbiological safety approach for agarose encapsulated porcine islets intended for clinical trials LS Gazda, J Collins, A Lovatt, RW Holdcraft, MJ Morin, D Galbraith, ... Xenotransplantation 23 (6), 444-463, 2016 | 46 | 2016 |
| Factors affecting transplant outcomes in diabetic nude mice receiving human, porcine, and nonhuman primate islets: analysis of 335 transplantations G Loganathan, ML Graham, DM Radosevich, SM Soltani, M Tiwari, ... Transplantation 95 (12), 1439-1447, 2013 | 45 | 2013 |
| The usefulness and limitations of the diabetic macaque model in evaluating long‐term porcine islet xenograft survival ML Graham, HJ Schuurman Xenotransplantation 20 (1), 5-17, 2013 | 40 | 2013 |
| Cyclosporine toxicity in immunosuppressed streptozotocin-diabetic nonhuman primates M Wijkstrom, N Kirchhof, M Graham, E Ingulli, RB Colvin, U Christians, ... Toxicology 207 (1), 117-127, 2005 | 39 | 2005 |
| Refining the high-dose streptozotocin-induced diabetic non-human primate model: an evaluation of risk factors and outcomes ML Graham, LA Mutch, EF Rieke, JA Kittredge, AW Faig, TA DuFour, ... Experimental Biology and Medicine 236 (10), 1218-1230, 2011 | 38 | 2011 |
| Effects of histone deacetylase inhibitor SAHA on effector and FOXP3+ regulatory T cells in rhesus macaques J Johnson, A Pahuja, M Graham, B Hering, WW Hancock, ... Transplantation proceedings 40 (2), 459-461, 2008 | 36 | 2008 |
| Mucosal microbiota and metabolome along the intestinal tract reveal a location-specific relationship C Yuan, M Graham, C Staley, S Subramanian Msystems 5 (3), 10.1128/msystems. 00055-20, 2020 | 28 | 2020 |
| A novel alternative placement site and technique for totally implantable vascular access ports in non‐human primates ML Graham, EF Rieke, M Dunning, LA Mutch, AM Craig, EK Zolondek, ... Journal of Medical Primatology 38 (3), 204-212, 2009 | 26 | 2009 |
