Cannabinoid receptor type 1 protects against age-related osteoporosis by regulating osteoblast and adipocyte differentiation in marrow stromal cells AI Idris, A Sophocleous, E Landao-Bassonga, M Canals, G Milligan, ... Cell Metabolism 10 (2), 139-147, 2009 | 198 | 2009 |
Quantitative analysis of bone and soft tissue by micro-computed tomography: applications to ex vivo and in vivo studies GM Campbell, A Sophocleous BoneKEy reports 3, 2014 | 183 | 2014 |
Regulation of bone mass, osteoclast function, and ovariectomy-induced bone loss by the type 2 cannabinoid receptor AI Idris, A Sophocleous, E Landao-Bassonga, RJ Van't Hof, SH Ralston Endocrinology 149 (11), 5619-5626, 2008 | 173 | 2008 |
The type 2 cannabinoid receptor regulates bone mass and ovariectomy-induced bone loss by affecting osteoblast differentiation and bone formation A Sophocleous, E Landao-Bassonga, RJ van ‘t Hof, AI Idris, SH Ralston Endocrinology 152 (6), 2141-2149, 2011 | 115 | 2011 |
Rodent models of osteoporosis A Sophocleous, AI Idris BoneKEy reports 3, 2014 | 97 | 2014 |
Heavy cannabis use is associated with low bone mineral density and an increased risk of fractures A Sophocleous, R Robertson, NB Ferreira, J McKenzie, WD Fraser, ... The American journal of medicine 130 (2), 214-221, 2017 | 73 | 2017 |
The type 2 cannabinoid receptor regulates susceptibility to osteoarthritis in mice A Sophocleous, AE Börjesson, DM Salter, SH Ralston Osteoarthritis and cartilage 23 (9), 1586-1594, 2015 | 47 | 2015 |
Combined deficiency of the Cnr1 and Cnr2 receptors protects against age‐related bone loss by osteoclast inhibition A Sophocleous, S Marino, D Kabir, SH Ralston, AI Idris Aging Cell 16 (5), 1051-1061, 2017 | 46 | 2017 |
Targeted sequencing of the Paget's disease associated 14q32 locus identifies several missense coding variants in RIN3 that predispose to Paget's disease of bone M Vallet, DC Soares, S Wani, A Sophocleous, J Warner, DM Salter, ... Human molecular genetics 24 (11), 3286-3295, 2015 | 39 | 2015 |
Bone cell-autonomous contribution of type 2 cannabinoid receptor to breast cancer-induced osteolysis A Sophocleous, S Marino, JG Logan, P Mollat, SH Ralston, AI Idris Journal of Biological Chemistry 290 (36), 22049-22060, 2015 | 35 | 2015 |
Genetic background modifies the effects of type 2 cannabinoid receptor deficiency on bone mass and bone turnover A Sophocleous, AI Idris, SH Ralston Calcified tissue international 94, 259-268, 2014 | 32 | 2014 |
Paradoxical effects of JZL184, an inhibitor of monoacylglycerol lipase, on bone remodelling in healthy and cancer-bearing mice S Marino, D de Ridder, RT Bishop, N Renema, M Ponzetti, ... EBioMedicine 44, 452-466, 2019 | 31 | 2019 |
Raman spectroscopy predicts the link between claw keratin and bone collagen structure in a rodent model of oestrogen deficiency MC Caraher, A Sophocleous, JR Beattie, O O'Driscoll, NM Cummins, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (2), 398-406, 2018 | 29 | 2018 |
Ovariectomy/orchiectomy in rodents A Sophocleous, AI Idris Bone research protocols, 261-267, 2019 | 26 | 2019 |
Selective tyrosine kinase inhibition of insulin‐like growth factor‐1 receptor inhibits human and mouse breast cancer–induced bone cell activity, bone remodeling, and osteolysis JG Logan, A Sophocleous, S Marino, M Muir, VG Brunton, AI Idris Journal of Bone and Mineral Research 28 (5), 1229-1242, 2013 | 18 | 2013 |
Osteoarthritis mouse model of destabilization of the medial meniscus A Sophocleous, C Huesa Bone Research Protocols, 281-293, 2019 | 17 | 2019 |
Modulation of strain-specific differences in gene expression by cannabinoid type 2 receptor deficiency A Sophocleous, AH Sims, AI Idris, SH Ralston Calcified tissue international 94, 423-432, 2014 | 15 | 2014 |
The type 2 cannabinoid receptor s (CB2) protects against age-related bone loss by affecting bone formation and CB2 agonists exhibit anabolic activity A Sophocleous, E Landao-Bassonga, R van't Hof, SH Ralston, AI Idris Bone 44 (2), S219, 2009 | 13 | 2009 |
JZL184, a monoacylglycerol lipase inhibitor, induces bone loss in a multiple myeloma model of immunocompetent mice S Marino, G Carrasco, B Li, KM Shah, DL Lath, A Sophocleous, ... Calcified Tissue International 107, 72-85, 2020 | 12 | 2020 |
Probiotics inhibit cartilage damage and progression of osteoarthritis in mice A Sophocleous, A Azfer, C Huesa, E Stylianou, SH Ralston Calcified tissue international 112 (1), 66-73, 2023 | 10 | 2023 |