| Leber congenital amaurosis linked to AIPL1: a mouse model reveals destabilization of cGMP phosphodiesterase V Ramamurthy, GA Niemi, TA Reh, JB Hurley Proceedings of the National Academy of Sciences 101 (38), 13897-13902, 2004 | 192 | 2004 |
| Topology of the integral membrane form of Escherichia coli SecA protein reveals multiple periplasmically exposed regions and modulation by ATP binding V Ramamurthy, D Oliver Journal of Biological Chemistry 272 (37), 23239-23246, 1997 | 133 | 1997 |
| Rod photoreceptor differentiation in fetal and infant human retina A Hendrickson, K Bumsted-O'Brien, R Natoli, V Ramamurthy, D Possin, ... Experimental eye research 87 (5), 415-426, 2008 | 131 | 2008 |
| Biochemical analysis of a dimerization domain mutation in RetGC-1 associated with dominant cone–rod dystrophy CL Tucker, SC Woodcock, RE Kelsell, V Ramamurthy, DM Hunt, ... Proceedings of the National Academy of Sciences 96 (16), 9039-9044, 1999 | 115 | 1999 |
| Functional characterization of missense mutations at codon 838 in retinal guanylate cyclase correlates with disease severity in patients with autosomal dominant cone–rod dystrophy SE Wilkie, RJ Newbold, E Deery, CE Walker, I Stinton, V Ramamurthy, ... Human molecular genetics 9 (20), 3065-3073, 2000 | 102 | 2000 |
| AIPL1, a protein implicated in Leber's congenital amaurosis, interacts with and aids in processing of farnesylated proteins V Ramamurthy, M Roberts, F van den Akker, G Niemi, TA Reh, JB Hurley Proceedings of the National Academy of Sciences 100 (22), 12630-12635, 2003 | 98 | 2003 |
| Interactions within the coiled-coil domain of RetGC-1 guanylyl cyclase are optimized for regulation rather than for high affinity V Ramamurthy, C Tucker, SE Wilkie, V Daggett, DM Hunt, JB Hurley Journal of Biological Chemistry 276 (28), 26218-26229, 2001 | 97 | 2001 |
| Identification of a region of interaction between Escherichia coli SecA and SecY proteins S Snyders, V Ramamurthy, D Oliver Journal of Biological Chemistry 272 (17), 11302-11306, 1997 | 95 | 1997 |
| Zebrafish rx3 and mab21l2 are required during eye morphogenesis BN Kennedy, GW Stearns, VA Smyth, V Ramamurthy, F van Eeden, ... Developmental biology 270 (2), 336-349, 2004 | 91 | 2004 |
| Mutations in PNPLA6 are linked to photoreceptor degeneration and various forms of childhood blindness S Kmoch, J Majewski, V Ramamurthy, S Cao, S Fahiminiya, H Ren, ... Nature communications 6 (1), 5614, 2015 | 90 | 2015 |
| Loss of MPC1 reprograms retinal metabolism to impair visual function A Grenell, Y Wang, M Yam, A Swarup, TL Dilan, A Hauer, JD Linton, ... Proceedings of the National Academy of Sciences 116 (9), 3530-3535, 2019 | 87 | 2019 |
| The Musashi 1 controls the splicing of photoreceptor-specific exons in the vertebrate retina D Murphy, B Cieply, R Carstens, V Ramamurthy, P Stoilov PLoS genetics 12 (8), e1006256, 2016 | 77 | 2016 |
| AIPL1, a protein associated with childhood blindness, interacts with α-subunit of rod phosphodiesterase (PDE6) and is essential for its proper assembly S Kolandaivelu, J Huang, JB Hurley, V Ramamurthy Journal of biological chemistry 284 (45), 30853-30861, 2009 | 69 | 2009 |
| The Leber congenital amaurosis protein, AIPL1, is needed for the viability and functioning of cone photoreceptor cells LT Kirschman, S Kolandaivelu, JM Frederick, L Dang, AFX Goldberg, ... Human molecular genetics 19 (6), 1076-1087, 2010 | 68 | 2010 |
| Nucleotide binding activity of seca homodimer is conformationally regulated by temperature and altered byprld and azi mutations M Schmidt, H Ding, V Ramamurthy, I Mukerji, D Oliver Journal of Biological Chemistry 275 (20), 15440-15448, 2000 | 61 | 2000 |
| Bardet–Biedl syndrome-8 (BBS8) protein is crucial for the development of outer segments in photoreceptor neurons TL Dilan, RK Singh, T Saravanan, A Moye, AFX Goldberg, P Stoilov, ... Human Molecular Genetics 27 (2), 283-294, 2018 | 60 | 2018 |
| Gene therapy using self-complementary Y733F capsid mutant AAV2/8 restores vision in a model of early onset Leber congenital amaurosis CA Ku, VA Chiodo, SL Boye, AFX Goldberg, T Li, WW Hauswirth, ... Human molecular genetics 20 (23), 4569-4581, 2011 | 57 | 2011 |
| Functional analyses of mutant recessive GUCY2D alleles identified in Leber congenital amaurosis patients: protein domain comparisons and dominant negative effects CL Tucker, V Ramamurthy, AL Pina, M Loyer, S Dharmaraj, Y Li, ... Mol Vis 10, 297-303, 2004 | 54 | 2004 |
| Alternative Splicing Shapes the Phenotype of a Mutation in BBS8 To Cause Nonsyndromic Retinitis Pigmentosa D Murphy, R Singh, S Kolandaivelu, V Ramamurthy, P Stoilov Molecular and cellular biology 35 (10), 1860-1870, 2015 | 47 | 2015 |
| Transducin translocation contributes to rod survival and enhances synaptic transmission from rods to rod bipolar cells A Majumder, J Pahlberg, KK Boyd, V Kerov, S Kolandaivelu, ... Proceedings of the National Academy of Sciences 110 (30), 12468-12473, 2013 | 46 | 2013 |
