| EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation W Béguelin, R Popovic, M Teater, Y Jiang, KL Bunting, M Rosen, H Shen, ... Cancer cell 23 (5), 677-692, 2013 | 909 | 2013 |
| Loss of BAP1 function leads to EZH2-dependent transformation LM LaFave, W Béguelin, R Koche, M Teater, B Spitzer, A Chramiec, ... Nature medicine 21 (11), 1344-1349, 2015 | 355 | 2015 |
| Molecular and genetic characterization of MHC deficiency identifies EZH2 as therapeutic target for enhancing immune recognition D Ennishi, K Takata, W Béguelin, G Duns, A Mottok, P Farinha, ... Cancer discovery 9 (4), 546-563, 2019 | 251 | 2019 |
| EZH2 and BCL6 cooperate to assemble CBX8-BCOR complex to repress bivalent promoters, mediate germinal center formation and lymphomagenesis W Béguelin, M Teater, MD Gearhart, MTC Fernández, RL Goldstein, ... Cancer cell 30 (2), 197-213, 2016 | 234 | 2016 |
| TNFα acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-κB-dependent pathways MA Rivas, RP Carnevale, CJ Proietti, C Rosemblit, W Beguelin, ... Experimental cell research 314 (3), 509-529, 2008 | 205 | 2008 |
| Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture N Yusufova, A Kloetgen, M Teater, A Osunsade, JM Camarillo, CR Chin, ... Nature 589 (7841), 299-305, 2021 | 184 | 2021 |
| Enhancer of zeste homolog 2 (EZH2) inhibitors N Gulati, W Béguelin, L Giulino-Roth Leukemia & lymphoma 59 (7), 1574-1585, 2018 | 183 | 2018 |
| EZH2 enables germinal centre formation through epigenetic silencing of CDKN1A and an Rb-E2F1 feedback loop W Béguelin, MA Rivas, MT Calvo Fernández, M Teater, A Purwada, ... Nature communications 8 (1), 877, 2017 | 162 | 2017 |
| Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma MG Cardenas, W Yu, W Beguelin, MR Teater, H Geng, RL Goldstein, ... The Journal of clinical investigation 126 (9), 3351-3362, 2016 | 152 | 2016 |
| TET2 deficiency causes germinal center hyperplasia, impairs plasma cell differentiation, and promotes B-cell lymphomagenesis PM Dominguez, H Ghamlouch, W Rosikiewicz, P Kumar, W Béguelin, ... Cancer discovery 8 (12), 1632-1653, 2018 | 147 | 2018 |
| Multi-tiered reorganization of the genome during B cell affinity maturation anchored by a germinal center-specific locus control region KL Bunting, TD Soong, R Singh, Y Jiang, W Béguelin, DW Poloway, ... Immunity 45 (3), 497-512, 2016 | 136 | 2016 |
| Hematopoietic Stem Cell Origin of BRAFV600E Mutations in Hairy Cell Leukemia SS Chung, E Kim, JH Park, YR Chung, P Lito, J Teruya-Feldstein, W Hu, ... Science translational medicine 6 (238), 238ra71-238ra71, 2014 | 131 | 2014 |
| Progesterone receptor induces ErbB-2 nuclear translocation to promote breast cancer growth via a novel transcriptional effect: ErbB-2 function as a coactivator of Stat3 W Béguelin, MC Díaz Flaqué, CJ Proietti, F Cayrol, MA Rivas, M Tkach, ... Molecular and cellular biology 30 (23), 5456-5472, 2010 | 118 | 2010 |
| Mutant EZH2 induces a pre-malignant lymphoma niche by reprogramming the immune response W Béguelin, M Teater, C Meydan, KB Hoehn, JM Phillip, AA Soshnev, ... Cancer cell 37 (5), 655-673. e11, 2020 | 117 | 2020 |
| p42/p44 MAPK-mediated Stat3 Ser727 phosphorylation is required for progestin-induced full activation of Stat3 and breast cancer growth M Tkach, C Rosemblit, MA Rivas, CJ Proietti Anastasi, MC Díaz Flaqué, ... Bioscientifica, 2013 | 99 | 2013 |
| IL10 receptor is a novel therapeutic target in DLBCLs W Béguelin, S Sawh, N Chambwe, FC Chan, Y Jiang, JW Choo, DW Scott, ... Leukemia 29 (8), 1684-1694, 2015 | 83 | 2015 |
| TBL1XR1 mutations drive extranodal lymphoma by inducing a pro-tumorigenic memory fate L Venturutti, M Teater, A Zhai, A Chadburn, L Babiker, D Kim, W Béguelin, ... Cell 182 (2), 297-316. e27, 2020 | 78 | 2020 |
| Activation of Stat3 by heregulin/ErbB-2 through the co-option of progesterone receptor signaling drives breast cancer growth CJ Proietti, C Rosemblit, W Beguelin, MA Rivas, MC Díaz Flaqué, ... Molecular and cellular biology 29 (5), 1249-1265, 2009 | 73 | 2009 |
| Genetic and epigenetic inactivation of SESTRIN1 controls mTORC1 and response to EZH2 inhibition in follicular lymphoma E Oricchio, N Katanayeva, MC Donaldson, S Sungalee, JP Pasion, ... Science translational medicine 9 (396), eaak9969, 2017 | 72 | 2017 |
| Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL A Pastore, F Gaiti, SX Lu, RM Brand, S Kulm, R Chaligne, H Gu, ... Nature communications 10 (1), 1874, 2019 | 69 | 2019 |
