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Alexandra Grote
Alexandra Grote
Postdoc at The Broad Institute of MIT and Harvard
Verified email at broadinstitute.org - Homepage
Title
Cited by
Cited by
Year
The genome of Onchocerca volvulus, agent of river blindness
JA Cotton, S Bennuru, A Grote, B Harsha, A Tracey, R Beech, SR Doyle, ...
Nature microbiology 2 (2), 1-12, 2016
1252016
Defining Brugia malayi and Wolbachia symbiosis by stage-specific dual RNA-seq
A Grote, D Voronin, T Ding, A Twaddle, TR Unnasch, S Lustigman, ...
PLoS Neglected Tropical Diseases 11 (3), e0005357, 2017
542017
Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont
S Bennuru, JA Cotton, JMC Ribeiro, A Grote, B Harsha, N Holroyd, ...
MBio 7 (6), 10.1128/mbio. 02028-16, 2016
512016
StrainGE: a toolkit to track and characterize low-abundance strains in complex microbial communities
LR van Dijk, BJ Walker, TJ Straub, CJ Worby, A Grote, HL Schreiber IV, ...
Genome biology 23 (1), 74, 2022
402022
Sex chromosome evolution in parasitic nematodes of humans
JM Foster, A Grote, J Mattick, A Tracey, YC Tsai, M Chung, JA Cotton, ...
Nature communications 11 (1), 1964, 2020
402020
Role of polyphosphate in thermophilic Synechococcus sp. from microbial mats
MR Gomez-Garcia, F Fazeli, A Grote, AR Grossman, D Bhaya
Journal of bacteriology 195 (15), 3309-3319, 2013
372013
Cysteine proteases during larval migration and development of helminths in their final host
A Grote, CR Caffrey, KM Rebello, D Smith, JP Dalton, S Lustigman
PLoS neglected tropical diseases 12 (8), e0005919, 2018
312018
Modulating the evolutionary trajectory of tolerance using antibiotics with different metabolic dependencies
EJ Zheng, IW Andrews, AT Grote, AL Manson, MA Alcantar, AM Earl, ...
Nature Communications 13 (1), 2525, 2022
262022
CRISPR-mediated Transfection of Brugia malayi
C Liu, A Grote, E Ghedin, TR Unnasch
PLoS neglected tropical diseases 14 (8), e0008627, 2020
232020
Pyruvate produced by Brugia spp. via glycolysis is essential for maintaining the mutualistic association between the parasite and its endosymbiont, Wolbachia
D Voronin, E Schnall, A Grote, S Jawahar, W Ali, TR Unnasch, E Ghedin, ...
PLoS pathogens 15 (9), e1008085, 2019
202019
Lessons from the genomes and transcriptomes of filarial nematodes
A Grote, S Lustigman, E Ghedin
Molecular and biochemical parasitology 215, 23-29, 2017
202017
Nearly complete genome sequence of Brugia malayi strain FR3
A Tracey, JM Foster, M Paulini, A Grote, J Mattick, YC Tsai, M Chung, ...
Microbiology Resource Announcements 9 (24), 10.1128/mra. 00154-20, 2020
152020
The role of'omics' in the quest to eliminate human filariasis
S Lustigman, A Grote, E Ghedin
PLoS neglected tropical diseases 11 (4), e0005464, 2017
142017
Modeling the metabolic interplay between a parasitic worm and its bacterial endosymbiont allows the identification of novel drug targets
DM Curran, A Grote, N Nursimulu, A Geber, D Voronin, DR Jones, ...
Elife 9, e51850, 2020
132020
Within-host evolution of bacterial pathogens during persistent infection of humans
A Grote, AM Earl
Current Opinion in Microbiology 70, 102197, 2022
122022
The genome of Onchocerca volvulus, agent of river blindness. Nat Microbiol. 2016; 2: 16216
JA Cotton, S Bennuru, A Grote, B Harsha, A Tracey, R Beech
11
A Meta-Analysis of Wolbachia Transcriptomics Reveals a Stage-Specific Wolbachia Transcriptional Response Shared Across Different Hosts
M Chung, PJ Basting, RS Patkus, A Grote, AN Luck, E Ghedin, BE Slatko, ...
G3: Genes, Genomes, Genetics 10 (9), 3243-3260, 2020
52020
Stage-specific transcriptome and proteome analyses of the filarial parasite Onchocerca volvulus and its Wolbachia endosymbiont. mBio 7: e02028-16
S Bennuru, JA Cotton, JM Ribeiro, A Grote, B Harsha, N Holroyd, ...
52016
Prediction pipeline for discovery of regulatory motifs associated with Brugia malayi molting
A Grote, Y Li, C Liu, D Voronin, A Geber, S Lustigman, TR Unnasch, ...
PLoS neglected tropical diseases 14 (6), e0008275, 2020
42020
Transcriptomics reveals how minocycline-colistin synergy overcomes antibiotic resistance in multidrug-resistant Klebsiella pneumoniae
T Brennan-Krohn, A Grote, S Rodriguez, JE Kirby, AM Earl
Antimicrobial Agents and Chemotherapy 66 (3), e01969-21, 2022
32022
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Articles 1–20