| Interleukin-6 and the acute phase response. PC Heinrich, JV Castell, T Andus Biochemical journal 265 (3), 621, 1990 | 3786 | 1990 |
| Interleukin‐6 is the major regulator of acute phase protein synthesis in adult human hepatocytes JV Castell, MJ Gómez-Lechón, M David, T Andus, T Geiger, R Trullenque, ... FEBS letters 242 (2), 237-239, 1989 | 1167 | 1989 |
| Acute-phase response of human hepatocytes: regulation of acute-phase protein synthesis by interleukin-6 JV Castell, MJ Gómez-lechón, M David, R Fabra, R Trullenque, ... Hepatology 12 (5), 1179-1186, 1990 | 991 | 1990 |
| Recombinant human interleukin-6 (IL-6/BSF-2/HSF) regulates the synthesis of acute phase proteins in human hepatocytes JV Castell, MJ Gómez-Lechón, M David, T Hirano, T Kishimoto, ... FEBS letters 232 (2), 347-350, 1988 | 642 | 1988 |
| Acute exacerbations of chronic obstructive pulmonary disease are accompanied by elevations of plasma fibrinogen and serum IL-6 levels JA Wedzicha, TAR Seemungal, PK MacCallum, EA Paul, GC Donaldson, ... Thrombosis and haemostasis 84 (08), 210-215, 2000 | 633 | 2000 |
| A human hepatocellular in vitro model to investigate steatosis MJ Gómez-Lechón, MT Donato, A Martínez-Romero, N Jiménez, ... Chemico-biological interactions 165 (2), 106-116, 2007 | 606 | 2007 |
| Cytochrome P450 expression in human hepatocytes and hepatoma cell lines: molecular mechanisms that determine lower expression in cultured cells C Rodríguez-Antona, MT Donato, A Boobis, RJ Edwards, PS Watts, ... Xenobiotica 32 (6), 505-520, 2002 | 466 | 2002 |
| Dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay: a quantitative method for oxidative stress assessment of nanoparticle-treated cells A Aranda, L Sequedo, L Tolosa, G Quintas, E Burello, JV Castell, ... Toxicology in vitro 27 (2), 954-963, 2013 | 439 | 2013 |
| Cell lines: a tool for in vitro drug metabolism studies MJ Gomez-Lechon, MT Donato, A Lahoz, JV Castell Current drug metabolism 9 (1), 1-11, 2008 | 407 | 2008 |
| Plasma clearance, organ distribution and target cells of interleukin‐6/hepatocyte‐stimulating factor in the rat JV Castell, T Geiger, V Gross, T Andus, E Walter, T Hirano, T Kishimoto, ... European Journal of Biochemistry 177 (2), 357-361, 1988 | 396 | 1988 |
| A microassay for measuring cytochrome P450IA1 and cytochrome P450IIB1 activities in intact human and rat hepatocytes cultured on 96-well plates MT Donato, MJ Gomezlechon, JV Castell Analytical biochemistry 213 (1), 29-33, 1993 | 373 | 1993 |
| Diclofenac toxicity to hepatocytes: a role for drug metabolism in cell toxicity R Bort, X Ponsoda, R Jover, MJ Gómez-Lechón, JV Castell Journal of Pharmacology and Experimental Therapeutics 288 (1), 65-72, 1999 | 366 | 1999 |
| Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells R Taléns-Visconti, A Bonora, R Jover, V Mirabet, F Carbonell, JV Castell, ... World journal of gastroenterology: WJG 12 (36), 5834, 2006 | 346 | 2006 |
| Hepatic metabolism of diclofenac: role of human CYP in the minor oxidative pathways R Bort, K Macé, A Boobis, MJ Gómez-Lechón, A Pfeifer, J Castell Biochemical pharmacology 58 (5), 787-796, 1999 | 320 | 1999 |
| Human hepatocytes in primary culture: the choice to investigate drug metabolism in man MJ Gomez-Lechon, MT Donato, JV Castell, R Jover Current drug metabolism 5 (5), 443-462, 2004 | 303 | 2004 |
| Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach JV Castell, MT Donato, MJ Gómez-Lechón Experimental and Toxicologic Pathology 57, 189-204, 2005 | 293 | 2005 |
| Human hepatocytes as a tool for studying toxicity and drug metabolism MJ Gomez-Lechon, MT Donato, JV Castell, R Jover Current drug metabolism 4 (4), 292-312, 2003 | 289 | 2003 |
| Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymes MT Donato, N Jiménez, JV Castell, MJ Gómez-Lechón Drug Metabolism and Disposition 32 (7), 699-706, 2004 | 281 | 2004 |
| Cytokine signaling during myocardial infarction: sequential appearance of IL-1 beta and IL-6 I Guillen, M Blanes, MJ Gomez-Lechon, JV Castell American Journal of Physiology-Regulatory, Integrative and Comparative …, 1995 | 280 | 1995 |
| Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirus‐mediated antisense targeting R Jover, R Bort, MJ Gómez‐Lechón, JV Castell Hepatology 33 (3), 668-675, 2001 | 277 | 2001 |
