Discovery of potent and selective inhibitors of the Escherichia coli M1-aminopeptidase via multicomponent solid-phase synthesis of tetrazole-peptidomimetics Y Méndez, G De Armas, I Pérez, T Rojas, ME Valdés-Tresanco, ... European Journal of Medicinal Chemistry 163, 481-499, 2019 | 38 | 2019 |
Combinatorial Multicomponent Access to Natural‐Products‐Inspired Peptidomimetics: Discovery of Selective Inhibitors of Microbial Metallo‐aminopeptidases Y Méndez, K Pérez‐Labrada, J González‐Bacerio, G Valdés, ... ChemMedChem 9 (10), 2351-2359, 2014 | 29 | 2014 |
KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library J González-Bacerio, SEC Maluf, Y Méndez, I Pascual, I Florent, PMS Melo, ... Bioorganic & Medicinal Chemistry 25 (17), 4628-4636, 2017 | 27 | 2017 |
Plasmodium falciparum M1-aminopeptidase: a promising target for the development of antimalarials J González-Bacerio, R Fando, A del Monte-Martínez, JL Charli, ... Current Drug Targets 15 (12), 1144-1165, 2014 | 18 | 2014 |
Improved purification and enzymatic properties of a mixture of Sticholysin I and II: isotoxins with hemolytic and phospholipase A2 activities from the sea anemone Stichodactyla … A del Monte-Martinez, J Gonzalez-Bacerio, L Romero, C Aragón, ... Protein Expression and Purification 95, 57-66, 2014 | 15 | 2014 |
High-level expression in Escherichia coli, purification and kinetic characterization of Plasmodium falciparum M1-aminopeptidase J González-Bacerio, J Osuna, A Ponce, R Fando, K Figarella, Y Méndez, ... Protein expression and purification 104, 103-114, 2014 | 14 | 2014 |
Development of a High-Throughput Screening Assay to Identify Inhibitors of the Major M17-Leucyl Aminopeptidase from Trypanosoma cruzi Using RapidFire Mass … M Izquierdo, D Lin, S O’Neill, M Zoltner, L Webster, A Hope, DW Gray, ... SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (9), 1064-1071, 2020 | 13 | 2020 |
Selective and oriented immobilization of (phospho) lipases from the Caribbean Sea anemone Stichodactyla helianthus (Ellis, 1768) by interfacial adsorption A del Monte-Martínez, J González-Bacerio, C Aragón-Abreu, ... Revista CENIC. Ciencias Biológicas 43 (1), 3-8, 2012 | 12 | 2012 |
High-Level Expression in Escherichia coli, Purification and Kinetic Characterization of LAPTc, a Trypanosoma cruzi M17-Aminopeptidase M Izquierdo, ME Aguado, M Zoltner, J González-Bacerio The Protein Journal 38, 167-180, 2019 | 11 | 2019 |
Rational design strategy as a novel immobilization methodology applied to lipases and phospholipases A del Monte-Martínez, BV Cutiño-Avila, J González-Bacerio Lipases and phospholipases: Methods and protocols, 243-283, 2018 | 11 | 2018 |
Structure-activity relationship of the inhibition of M1-aminopeptidases from Escherichia coli (ePepN) and Plasmodium falciparum (PfA-M1) by bestatin-derived peptidomimetics … AC Varela, G De Armas, Y Méndez, M Izquierdo, MA del Rivero, ... Revista Cubana de Ciencias Biológicas 7 (1), 21, 2019 | 10 | 2019 |
Kinetic characterization of recombinant PfAM1, a M1-aminopeptidase from Plasmodium falciparum (Aconoidasida: Plasmodiidae), using fluorogenic peptide substrates. JO González-Bacerio, MÁ Chávez, MA del Rivero, AK Carmona, ... Cuban Journal of Biological Sciences/Revista Cubana de Ciencias Biológicas 4 (2), 2015 | 10 | 2015 |
Modeling and experimental validation of covalent immobilization of Trametes maxima laccase on glyoxyl and MANA‐Sepharose CL 4B supports, for the use in … BV Cutiño‐Avila, MI Sánchez‐López, Y Cárdenas‐Moreno, ... Biotechnology and Applied Biochemistry 69 (2), 479-491, 2022 | 8 | 2022 |
Aplicación de enzimas en biocatálisis. Perspectivas de la utilización de nanoarreglos como biocatalizadores A del Monte-Martínez, BV Cutiño-Avila, JO González-Bacerio, ... Revista Cubana de Ciencias Biológicas 2 (2), 2013 | 7 | 2013 |
Rational design and synthesis of affinity matrices based on proteases immobilized onto cellulose membranes A del Monte-Martínez, J González-Bacerio, B Cutiño-Avila, J Rojas, ... Preparative Biochemistry and Biotechnology 47 (8), 745-753, 2017 | 6 | 2017 |
Esters biotransformation by immobilized interfacial esterases from the Caribbean Sea anemone Stichodactyla helianthus A del Monte-Martínez, J González-Bacerio, B Cutiño-Avila, R Ruiz, ... Biotecnología Aplicada 32 (3), 3201-3210, 2015 | 5 | 2015 |
Expression in Escherichia coli, purification and kinetic characterization of LAPLm, a Leishmania major M17-aminopeptidase ME Aguado, M González-Matos, M Izquierdo, J Quintana, MC Field, ... Protein Expression and Purification 183, 105877, 2021 | 4 | 2021 |
Oxidoreductase enzymes: Characteristics, applications, and challenges as a biocatalyst Y Cárdenas‐Moreno, J González‐Bacerio, H García Arellano, ... Biotechnology and Applied Biochemistry 70 (6), 2108-2135, 2023 | 3 | 2023 |
Using microbial metalo-aminopeptidases as targets in human infectious diseases J González-Bacerio, M Izquierdo, ME Aguado, AC Varela, ... Microbial Cell 8 (10), 239, 2021 | 3 | 2021 |
KBE009: A Bestatin-Like Inhibitor of the Trypanosoma cruzi Acidic M17 Aminopeptidase with In Vitro Anti-Trypanosomal Activity J González-Bacerio, I Arocha, ME Aguado, Y Méndez, S Marsiccobetre, ... Life 11 (10), 1037, 2021 | 3 | 2021 |