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Jorge Gonzalez-Bacerio
Jorge Gonzalez-Bacerio
Departamento de Bioquimica, Centro de Estudio de Proteínas, Facultad de Biología, Universidad de La Habana
Verified email at fbio.uh.cu
Title
Cited by
Cited by
Year
Discovery of potent and selective inhibitors of the Escherichia coli M1-aminopeptidase via multicomponent solid-phase synthesis of tetrazole-peptidomimetics
Y Méndez, G De Armas, I Pérez, T Rojas, ME Valdés-Tresanco, ...
European Journal of Medicinal Chemistry 163, 481-499, 2019
382019
Combinatorial Multicomponent Access to Natural‐Products‐Inspired Peptidomimetics: Discovery of Selective Inhibitors of Microbial Metallo‐aminopeptidases
Y Méndez, K Pérez‐Labrada, J González‐Bacerio, G Valdés, ...
ChemMedChem 9 (10), 2351-2359, 2014
292014
KBE009: An antimalarial bestatin-like inhibitor of the Plasmodium falciparum M1 aminopeptidase discovered in an Ugi multicomponent reaction-derived peptidomimetic library
J González-Bacerio, SEC Maluf, Y Méndez, I Pascual, I Florent, PMS Melo, ...
Bioorganic & Medicinal Chemistry 25 (17), 4628-4636, 2017
272017
Plasmodium falciparum M1-aminopeptidase: a promising target for the development of antimalarials
J González-Bacerio, R Fando, A del Monte-Martínez, JL Charli, ...
Current Drug Targets 15 (12), 1144-1165, 2014
182014
Improved purification and enzymatic properties of a mixture of Sticholysin I and II: isotoxins with hemolytic and phospholipase A2 activities from the sea anemone Stichodactyla …
A del Monte-Martinez, J Gonzalez-Bacerio, L Romero, C Aragón, ...
Protein Expression and Purification 95, 57-66, 2014
152014
High-level expression in Escherichia coli, purification and kinetic characterization of Plasmodium falciparum M1-aminopeptidase
J González-Bacerio, J Osuna, A Ponce, R Fando, K Figarella, Y Méndez, ...
Protein expression and purification 104, 103-114, 2014
142014
Development of a High-Throughput Screening Assay to Identify Inhibitors of the Major M17-Leucyl Aminopeptidase from Trypanosoma cruzi Using RapidFire Mass …
M Izquierdo, D Lin, S O’Neill, M Zoltner, L Webster, A Hope, DW Gray, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (9), 1064-1071, 2020
132020
Selective and oriented immobilization of (phospho) lipases from the Caribbean Sea anemone Stichodactyla helianthus (Ellis, 1768) by interfacial adsorption
A del Monte-Martínez, J González-Bacerio, C Aragón-Abreu, ...
Revista CENIC. Ciencias Biológicas 43 (1), 3-8, 2012
122012
High-Level Expression in Escherichia coli, Purification and Kinetic Characterization of LAPTc, a Trypanosoma cruzi M17-Aminopeptidase
M Izquierdo, ME Aguado, M Zoltner, J González-Bacerio
The Protein Journal 38, 167-180, 2019
112019
Rational design strategy as a novel immobilization methodology applied to lipases and phospholipases
A del Monte-Martínez, BV Cutiño-Avila, J González-Bacerio
Lipases and phospholipases: Methods and protocols, 243-283, 2018
112018
Structure-activity relationship of the inhibition of M1-aminopeptidases from Escherichia coli (ePepN) and Plasmodium falciparum (PfA-M1) by bestatin-derived peptidomimetics …
AC Varela, G De Armas, Y Méndez, M Izquierdo, MA del Rivero, ...
Revista Cubana de Ciencias Biológicas 7 (1), 21, 2019
102019
Kinetic characterization of recombinant PfAM1, a M1-aminopeptidase from Plasmodium falciparum (Aconoidasida: Plasmodiidae), using fluorogenic peptide substrates.
JO González-Bacerio, MÁ Chávez, MA del Rivero, AK Carmona, ...
Cuban Journal of Biological Sciences/Revista Cubana de Ciencias Biológicas 4 (2), 2015
102015
Modeling and experimental validation of covalent immobilization of Trametes maxima laccase on glyoxyl and MANA‐Sepharose CL 4B supports, for the use in …
BV Cutiño‐Avila, MI Sánchez‐López, Y Cárdenas‐Moreno, ...
Biotechnology and Applied Biochemistry 69 (2), 479-491, 2022
82022
Aplicación de enzimas en biocatálisis. Perspectivas de la utilización de nanoarreglos como biocatalizadores
A del Monte-Martínez, BV Cutiño-Avila, JO González-Bacerio, ...
Revista Cubana de Ciencias Biológicas 2 (2), 2013
72013
Rational design and synthesis of affinity matrices based on proteases immobilized onto cellulose membranes
A del Monte-Martínez, J González-Bacerio, B Cutiño-Avila, J Rojas, ...
Preparative Biochemistry and Biotechnology 47 (8), 745-753, 2017
62017
Esters biotransformation by immobilized interfacial esterases from the Caribbean Sea anemone Stichodactyla helianthus
A del Monte-Martínez, J González-Bacerio, B Cutiño-Avila, R Ruiz, ...
Biotecnología Aplicada 32 (3), 3201-3210, 2015
52015
Expression in Escherichia coli, purification and kinetic characterization of LAPLm, a Leishmania major M17-aminopeptidase
ME Aguado, M González-Matos, M Izquierdo, J Quintana, MC Field, ...
Protein Expression and Purification 183, 105877, 2021
42021
Oxidoreductase enzymes: Characteristics, applications, and challenges as a biocatalyst
Y Cárdenas‐Moreno, J González‐Bacerio, H García Arellano, ...
Biotechnology and Applied Biochemistry 70 (6), 2108-2135, 2023
32023
Using microbial metalo-aminopeptidases as targets in human infectious diseases
J González-Bacerio, M Izquierdo, ME Aguado, AC Varela, ...
Microbial Cell 8 (10), 239, 2021
32021
KBE009: A Bestatin-Like Inhibitor of the Trypanosoma cruzi Acidic M17 Aminopeptidase with In Vitro Anti-Trypanosomal Activity
J González-Bacerio, I Arocha, ME Aguado, Y Méndez, S Marsiccobetre, ...
Life 11 (10), 1037, 2021
32021
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