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Bin Xu
Bin Xu
BRITE Institute of North Carolina Central Univ; Affiliated faculty, Duke/UNC Alz Dis Res Ctr
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Cited by
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Year
Natural product-based nanomedicine: recent advances and issues
R Watkins, L Wu, C Zhang, RM Davis, B Xu
International journal of nanomedicine, 6055-6074, 2015
4022015
Natural product-based amyloid inhibitors
P Velander, L Wu, F Henderson, S Zhang, DR Bevan, B Xu
Biochemical pharmacology 139, 40-55, 2017
1932017
Crystal structure of a γδ T-cell receptor specific for the human MHC class I homolog MICA
B Xu, JC Pizarro, MA Holmes, C McBeth, V Groh, T Spies, RK Strong
Proceedings of the National Academy of Sciences 108 (6), 2414-2419, 2011
1822011
How insulin binds: The B-chain α-helix contacts the L1 β-helix of the insulin receptor
K Huang, B Xu, SQ Hu, YC Chu, Q Hua, Y Qu, B Li, S Wang, R Wang, ...
Journal of molecular biology 341 (2), 529-550, 2004
962004
Diabetes-Associated Mutations in Insulin:  Consecutive Residues in the B Chain Contact Distinct Domains of the Insulin Receptor,
B Xu, SQ Hu, YC Chu, K Huang, SH Nakagawa, J Whittaker, ...
Biochemistry 43 (26), 8356-8372, 2004
732004
Amylin amyloid inhibition by flavonoid baicalein: key roles of its vicinal dihydroxyl groups of the catechol moiety
P Velander, L Wu, WK Ray, RF Helm, B Xu
Biochemistry 55 (31), 4255-4258, 2016
672016
An Achilles' heel in an amyloidogenic protein and its repair: insulin fibrillation and therapeutic design
Y Yang, A Petkova, K Huang, B Xu, Q Hua, IJ Ye, YC Chu, SQ Hu, ...
Journal of biological chemistry 285 (14), 10806-10821, 2010
642010
Olive component oleuropein promotes β-cell insulin secretion and protects β-cells from amylin amyloid-induced cytotoxicity
L Wu, P Velander, D Liu, B Xu
Biochemistry 56 (38), 5035-5039, 2017
582017
Diabetes-Associated Mutations in Human Insulin:  Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama,
Z Wan, K Huang, B Xu, SQ Hu, S Wang, YC Chu, PG Katsoyannis, ...
Biochemistry 44 (13), 5000-5016, 2005
572005
GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro
A Wang, J Luo, W Moore, H Alkhalidy, L Wu, J Zhang, W Zhen, Y Wang, ...
Scientific reports 6 (1), 34302, 2016
562016
Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues
Z Wan, B Xu, K Huang, YC Chu, B Li, SH Nakagawa, Y Qu, SQ Hu, ...
Biochemistry 43 (51), 16119-16133, 2004
542004
Early preclinical detection of prions in the skin of prion-infected animals
Z Wang, M Manca, A Foutz, MV Camacho, GJ Raymond, B Race, CD Orru, ...
Nature communications 10 (1), 247, 2019
532019
Decoding the Cryptic Active Conformation of a Protein by Synthetic Photoscanning: INSULIN INSERTS A DETACHABLE ARM BETWEEN RECEPTOR DOMAINS*♦
B Xu, K Huang, YC Chu, SQ Hu, S Nakagawa, S Wang, RY Wang, ...
Journal of biological chemistry 284 (21), 14597-14608, 2009
502009
Chiral mutagenesis of insulin’s hidden receptor-binding surface: structure of an Allo-isoleucineA2 analogue
B Xu, Q Hua, SH Nakagawa, W Jia, YC Chu, PG Katsoyannis, MA Weiss
Journal of molecular biology 316 (3), 435-441, 2002
502002
A cavity‐forming mutation in insulin induces segmental unfolding of a surrounding α‐helix
B Xu, QX Hua, SH Nakagawa, W Jia, YC Chu, PG Katsoyannis, MA Weiss
Protein science 11 (1), 104-116, 2002
462002
Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS*♦
Q Hua, B Xu, K Huang, SQ Hu, S Nakagawa, W Jia, S Wang, J Whittaker, ...
Journal of biological chemistry 284 (21), 14586-14596, 2009
452009
Protein structure and the spandrels of San Marco: insulin's receptor-binding surface is buttressed by an invariant leucine essential for its stability
MA Weiss, SH Nakagawa, W Jia, B Xu, Q Hua, YC Chu, R Wang, ...
Biochemistry 41 (3), 809-819, 2002
402002
Diabetes-associated mutations in insulin identify invariant receptor contacts
B Xu, SQ Hu, YC Chu, S Wang, R Wang, SH Nakagawa, PG Katsoyannis, ...
Diabetes 53 (6), 1599-1602, 2004
312004
Phytonutrient genistein is a survival factor for pancreatic β-cells via GPR30-mediated mechanism
J Luo, A Wang, W Zhen, Y Wang, H Si, Z Jia, H Alkhalidy, Z Cheng, ...
The Journal of nutritional biochemistry 58, 59-70, 2018
292018
Crystal Structure of allo-IleA2-Insulin, an Inactive Chiral Analogue:  Implications for the Mechanism of Receptor Binding,
Z Wan, B Xu, YC Chu, PG Katsoyannis, MA Weiss
Biochemistry 42 (44), 12770-12783, 2003
242003
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