Natural product-based nanomedicine: recent advances and issues R Watkins, L Wu, C Zhang, RM Davis, B Xu International journal of nanomedicine, 6055-6074, 2015 | 402 | 2015 |
Natural product-based amyloid inhibitors P Velander, L Wu, F Henderson, S Zhang, DR Bevan, B Xu Biochemical pharmacology 139, 40-55, 2017 | 193 | 2017 |
Crystal structure of a γδ T-cell receptor specific for the human MHC class I homolog MICA B Xu, JC Pizarro, MA Holmes, C McBeth, V Groh, T Spies, RK Strong Proceedings of the National Academy of Sciences 108 (6), 2414-2419, 2011 | 182 | 2011 |
How insulin binds: The B-chain α-helix contacts the L1 β-helix of the insulin receptor K Huang, B Xu, SQ Hu, YC Chu, Q Hua, Y Qu, B Li, S Wang, R Wang, ... Journal of molecular biology 341 (2), 529-550, 2004 | 96 | 2004 |
Diabetes-Associated Mutations in Insulin: Consecutive Residues in the B Chain Contact Distinct Domains of the Insulin Receptor, B Xu, SQ Hu, YC Chu, K Huang, SH Nakagawa, J Whittaker, ... Biochemistry 43 (26), 8356-8372, 2004 | 73 | 2004 |
Amylin amyloid inhibition by flavonoid baicalein: key roles of its vicinal dihydroxyl groups of the catechol moiety P Velander, L Wu, WK Ray, RF Helm, B Xu Biochemistry 55 (31), 4255-4258, 2016 | 67 | 2016 |
An Achilles' heel in an amyloidogenic protein and its repair: insulin fibrillation and therapeutic design Y Yang, A Petkova, K Huang, B Xu, Q Hua, IJ Ye, YC Chu, SQ Hu, ... Journal of biological chemistry 285 (14), 10806-10821, 2010 | 64 | 2010 |
Olive component oleuropein promotes β-cell insulin secretion and protects β-cells from amylin amyloid-induced cytotoxicity L Wu, P Velander, D Liu, B Xu Biochemistry 56 (38), 5035-5039, 2017 | 58 | 2017 |
Diabetes-Associated Mutations in Human Insulin: Crystal Structure and Photo-Cross-Linking Studies of A-Chain Variant Insulin Wakayama, Z Wan, K Huang, B Xu, SQ Hu, S Wang, YC Chu, PG Katsoyannis, ... Biochemistry 44 (13), 5000-5016, 2005 | 57 | 2005 |
GPR30 regulates diet-induced adiposity in female mice and adipogenesis in vitro A Wang, J Luo, W Moore, H Alkhalidy, L Wu, J Zhang, W Zhen, Y Wang, ... Scientific reports 6 (1), 34302, 2016 | 56 | 2016 |
Enhancing the activity of insulin at the receptor interface: crystal structure and photo-cross-linking of A8 analogues Z Wan, B Xu, K Huang, YC Chu, B Li, SH Nakagawa, Y Qu, SQ Hu, ... Biochemistry 43 (51), 16119-16133, 2004 | 54 | 2004 |
Early preclinical detection of prions in the skin of prion-infected animals Z Wang, M Manca, A Foutz, MV Camacho, GJ Raymond, B Race, CD Orru, ... Nature communications 10 (1), 247, 2019 | 53 | 2019 |
Decoding the Cryptic Active Conformation of a Protein by Synthetic Photoscanning: INSULIN INSERTS A DETACHABLE ARM BETWEEN RECEPTOR DOMAINS*♦ B Xu, K Huang, YC Chu, SQ Hu, S Nakagawa, S Wang, RY Wang, ... Journal of biological chemistry 284 (21), 14597-14608, 2009 | 50 | 2009 |
Chiral mutagenesis of insulin’s hidden receptor-binding surface: structure of an Allo-isoleucineA2 analogue B Xu, Q Hua, SH Nakagawa, W Jia, YC Chu, PG Katsoyannis, MA Weiss Journal of molecular biology 316 (3), 435-441, 2002 | 50 | 2002 |
A cavity‐forming mutation in insulin induces segmental unfolding of a surrounding α‐helix B Xu, QX Hua, SH Nakagawa, W Jia, YC Chu, PG Katsoyannis, MA Weiss Protein science 11 (1), 104-116, 2002 | 46 | 2002 |
Enhancing the Activity of a Protein by Stereospecific Unfolding: CONFORMATIONAL LIFE CYCLE OF INSULIN AND ITS EVOLUTIONARY ORIGINS*♦ Q Hua, B Xu, K Huang, SQ Hu, S Nakagawa, W Jia, S Wang, J Whittaker, ... Journal of biological chemistry 284 (21), 14586-14596, 2009 | 45 | 2009 |
Protein structure and the spandrels of San Marco: insulin's receptor-binding surface is buttressed by an invariant leucine essential for its stability MA Weiss, SH Nakagawa, W Jia, B Xu, Q Hua, YC Chu, R Wang, ... Biochemistry 41 (3), 809-819, 2002 | 40 | 2002 |
Diabetes-associated mutations in insulin identify invariant receptor contacts B Xu, SQ Hu, YC Chu, S Wang, R Wang, SH Nakagawa, PG Katsoyannis, ... Diabetes 53 (6), 1599-1602, 2004 | 31 | 2004 |
Phytonutrient genistein is a survival factor for pancreatic β-cells via GPR30-mediated mechanism J Luo, A Wang, W Zhen, Y Wang, H Si, Z Jia, H Alkhalidy, Z Cheng, ... The Journal of nutritional biochemistry 58, 59-70, 2018 | 29 | 2018 |
Crystal Structure of allo-IleA2-Insulin, an Inactive Chiral Analogue: Implications for the Mechanism of Receptor Binding, Z Wan, B Xu, YC Chu, PG Katsoyannis, MA Weiss Biochemistry 42 (44), 12770-12783, 2003 | 24 | 2003 |