MicroRNA-21 plays a role in hypoxia-mediated pulmonary artery smooth muscle cell proliferation and migration J Sarkar, D Gou, P Turaka, E Viktorova, R Ramchandran, JU Raj American Journal of Physiology-Lung Cellular and Molecular Physiology 299 (6 …, 2010 | 256 | 2010 |
Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells M Tauseef, V Kini, N Knezevic, M Brannan, R Ramchandaran, H Fyrst, ... Circulation research 103 (10), 1164-1172, 2008 | 211 | 2008 |
miR-210 has an antiapoptotic effect in pulmonary artery smooth muscle cells during hypoxia D Gou, R Ramchandran, X Peng, L Yao, K Kang, J Sarkar, Z Wang, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 303 (8 …, 2012 | 154 | 2012 |
MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle … K Kang, X Peng, X Zhang, Y Wang, L Zhang, L Gao, T Weng, H Zhang, ... Journal of Biological Chemistry 288 (35), 25414-25427, 2013 | 141 | 2013 |
Nonmuscle myosin light-chain kinase mediates neutrophil transmigration in sepsis-induced lung inflammation by activating β2 integrins J Xu, XP Gao, R Ramchandran, YY Zhao, SM Vogel, AB Malik Nature immunology 9 (8), 880-886, 2008 | 126 | 2008 |
Cdc42 regulates adherens junction stability and endothelial permeability by inducing α-catenin interaction with the vascular endothelial cadherin complex MT Broman, P Kouklis, X Gao, R Ramchandran, RF Neamu, RD Minshall, ... Circulation research 98 (1), 73-80, 2006 | 120 | 2006 |
Regulated cleavage-secretion of the membrane-bound angiotensin-converting enzyme. R Ramchandran, GC Sen, K Misono, I Sen Journal of Biological Chemistry 269 (3), 2125-2130, 1994 | 117 | 1994 |
Sphingosine kinase 1/S1P signaling contributes to pulmonary fibrosis by activating Hippo/YAP pathway and mitochondrial reactive oxygen species in lung fibroblasts LS Huang, T Sudhadevi, P Fu, PK Punathil-Kannan, DL Ebenezer, ... International journal of molecular sciences 21 (6), 2064, 2020 | 86 | 2020 |
Lipid mediators regulate pulmonary fibrosis: potential mechanisms and signaling pathways V Suryadevara, R Ramchandran, DW Kamp, V Natarajan International Journal of Molecular Sciences 21 (12), 4257, 2020 | 85 | 2020 |
The distal ectodomain of angiotensin-converting enzyme regulates its cleavage-secretion from the cell surface R Sadhukhan, GC Sen, R Ramchandran, I Sen Proceedings of the National Academy of Sciences 95 (1), 138-143, 1998 | 85 | 1998 |
Nuclear myosin I is necessary for the formation of the first phosphodiester bond during transcription initiation by RNA polymerase II WA Hofmann, GM Vargas, R Ramchandran, L Stojiljkovic, JA Goodrich, ... Journal of cellular biochemistry 99 (4), 1001-1009, 2006 | 78 | 2006 |
MicroRNA-223 attenuates hypoxia-induced vascular remodeling by targeting RhoB/MLC2 in pulmonary arterial smooth muscle cells Y Zeng, X Zhang, K Kang, J Chen, Z Wu, J Huang, W Lu, Y Chen, J Zhang, ... Scientific reports 6 (1), 24900, 2016 | 75 | 2016 |
Hypoxia inducible factor-1 mediates expression of miR-322: potential role in proliferation and migration of pulmonary arterial smooth muscle cells Y Zeng, H Liu, K Kang, Z Wang, G Hui, X Zhang, J Zhong, W Peng, ... Scientific reports 5 (1), 12098, 2015 | 67 | 2015 |
Pulmonary artery smooth muscle cell proliferation and migration in fetal lambs acclimatized to high-altitude long-term hypoxia: role of histone acetylation Q Yang, Z Lu, R Ramchandran, LD Longo, JU Raj American Journal of Physiology-Lung Cellular and Molecular Physiology 303 …, 2012 | 65 | 2012 |
Hypoxia-induced pulmonary arterial smooth muscle cell proliferation is controlled by forkhead box M1 A Raghavan, G Zhou, Q Zhou, JCF Ibe, R Ramchandran, Q Yang, ... American journal of respiratory cell and molecular biology 46 (4), 431-436, 2012 | 61 | 2012 |
IGF-1 signaling in neonatal hypoxia-induced pulmonary hypertension: role of epigenetic regulation Q Yang, M Sun, R Ramchandran, JU Raj Vascular pharmacology 73, 20-31, 2015 | 55 | 2015 |
Cleavage processing of angiotensin-converting enzyme by a membrane-associated metalloprotease R Ramchandran, I Sen Biochemistry 34 (39), 12645-12652, 1995 | 53 | 1995 |
Critical role of Cdc42 in mediating endothelial barrier protection in vivo R Ramchandran, D Mehta, SM Vogel, MK Mirza, P Kouklis, AB Malik American Journal of Physiology-Lung Cellular and Molecular Physiology 295 (2 …, 2008 | 50 | 2008 |
Angiotensinergic stimulation of vascular endothelium in mice causes hypotension, bradycardia, and attenuated angiotensin response R Ramchandran, T Takezako, Y Saad, L Stull, B Fink, H Yamada, ... Proceedings of the National Academy of Sciences 103 (50), 19087-19092, 2006 | 50 | 2006 |
Smooth muscle insulin-like growth factor-1 mediates hypoxia-induced pulmonary hypertension in neonatal mice M Sun, R Ramchandran, J Chen, Q Yang, JU Raj American journal of respiratory cell and molecular biology 55 (6), 779-791, 2016 | 43 | 2016 |