Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways GH Werstuck, SR Lentz, S Dayal, GS Hossain, SK Sood, YY Shi, J Zhou, ... The Journal of clinical investigation 107 (10), 1263-1273, 2001 | 892 | 2001 |
Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease RC Austin, SR Lentz, GH Werstuck Cell Death & Differentiation 11 (1), S56-S64, 2004 | 628 | 2004 |
Hyperhomocysteinemia and its role in the development of atherosclerosis ABL De Koning, GH Werstuck, J Zhou, RC Austin Clinical biochemistry 36 (6), 431-441, 2003 | 344 | 2003 |
Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3 AJ Kim, Y Shi, RC Austin, GH Werstuck Journal of cell science 118 (1), 89-99, 2005 | 315 | 2005 |
TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia GS Hossain, JV van Thienen, GH Werstuck, J Zhou, SK Sood, ... Journal of Biological Chemistry 278 (32), 30317-30327, 2003 | 273 | 2003 |
Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2 SM Colgan, D Tang, GH Werstuck, RC Austin The international journal of biochemistry & cell biology 39 (10), 1843-1851, 2007 | 218 | 2007 |
Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice J Zhou, GH Werstuck, S Lhoták, ABL de Koning, SK Sood, GS Hossain, ... Circulation 110 (2), 207-213, 2004 | 217 | 2004 |
Glucosamine-induced endoplasmic reticulum dysfunction is associated with accelerated atherosclerosis in a hyperglycemic mouse model GH Werstuck, MI Khan, G Femia, AJ Kim, V Tedesco, B Trigatti, Y Shi Diabetes 55 (1), 93-101, 2006 | 182 | 2006 |
Interleukin‐15 contributes to the regulation of murine adipose tissue and human adipocytes NG Barra, S Reid, R MacKenzie, G Werstuck, BL Trigatti, C Richards, ... Obesity 18 (8), 1601-1607, 2010 | 136 | 2010 |
Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T DR Beriault, GH Werstuck Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (10), 2293-2301, 2013 | 121 | 2013 |
The role of estrogen in insulin resistance: a review of clinical and preclinical data M De Paoli, A Zakharia, GH Werstuck The American journal of pathology 191 (9), 1490-1498, 2021 | 110 | 2021 |
Effect of leptin on vascular calcification in apolipoprotein E–deficient mice M Zeadin, M Butcher, G Werstuck, M Khan, CK Yee, SG Shaughnessy Arteriosclerosis, thrombosis, and vascular biology 29 (12), 2069-2075, 2009 | 100 | 2009 |
Hexosamine biosynthesis pathway flux promotes endoplasmic reticulum stress, lipid accumulation, and inflammatory gene expression in hepatic cells AT Sage, LA Walter, Y Shi, MI Khan, H Kaneto, A Capretta, GH Werstuck American Journal of Physiology-Endocrinology and Metabolism 298 (3), E499-E511, 2010 | 99 | 2010 |
Valproate attenuates accelerated atherosclerosis in hyperglycemic apoE-deficient mice: evidence in support of a role for endoplasmic reticulum stress and glycogen synthase … AJ Bowes, MI Khan, Y Shi, L Robertson, GH Werstuck The American journal of pathology 174 (1), 330-342, 2009 | 99 | 2009 |
Molecular mechanisms linking diabetes to the accelerated development of atherosclerosis MG Zeadin, CI Petlura, GH Werstuck Canadian journal of diabetes 37 (5), 345-350, 2013 | 96 | 2013 |
Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin-binding protein (GRP78/BiP) inhibits tissue factor procoagulant activity LM Watson, AKC Chan, LR Berry, J Li, SK Sood, JG Dickhout, L Xu, ... Journal of Biological Chemistry 278 (19), 17438-17447, 2003 | 82 | 2003 |
Evidence supporting a role for endoplasmic reticulum stress in the development of atherosclerosis in a hyperglycaemic mouse model MI Khan, BA Pichna, Y Shi, AJ Bowes, GH Werstuck Antioxidants & redox signaling 11 (9), 2289-2298, 2009 | 78 | 2009 |
GnRH antagonist associates with less adiposity and reduced characteristics of metabolic syndrome and atherosclerosis compared with orchiectomy and GnRH agonist in a preclinical … SN Hopmans, WCM Duivenvoorden, GH Werstuck, L Klotz, JH Pinthus Urologic oncology: Seminars and original investigations 32 (8), 1126-1134, 2014 | 76 | 2014 |
Comprehensive plasma metabolomic analyses of atherosclerotic progression reveal alterations in glycerophospholipid and sphingolipid metabolism in apolipoprotein E-deficient mice VT Dang, A Huang, LH Zhong, Y Shi, GH Werstuck Scientific reports 6 (1), 35037, 2016 | 72 | 2016 |
Metabolic syndrome and acute hyperglycemia are associated with endoplasmic reticulum stress in human mononuclear cells AT Sage, S Holtby‐Ottenhof, Y Shi, S Damjanovic, AM Sharma, ... Obesity 20 (4), 748-755, 2012 | 71 | 2012 |