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Geoff Werstuck
Geoff Werstuck
Professor, McMaster University
Verified email at taari.ca
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Cited by
Year
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathways
GH Werstuck, SR Lentz, S Dayal, GS Hossain, SK Sood, YY Shi, J Zhou, ...
The Journal of clinical investigation 107 (10), 1263-1273, 2001
8922001
Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease
RC Austin, SR Lentz, GH Werstuck
Cell Death & Differentiation 11 (1), S56-S64, 2004
6282004
Hyperhomocysteinemia and its role in the development of atherosclerosis
ABL De Koning, GH Werstuck, J Zhou, RC Austin
Clinical biochemistry 36 (6), 431-441, 2003
3442003
Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3
AJ Kim, Y Shi, RC Austin, GH Werstuck
Journal of cell science 118 (1), 89-99, 2005
3152005
TDAG51 is induced by homocysteine, promotes detachment-mediated programmed cell death, and contributes to the development of atherosclerosis in hyperhomocysteinemia
GS Hossain, JV van Thienen, GH Werstuck, J Zhou, SK Sood, ...
Journal of Biological Chemistry 278 (32), 30317-30327, 2003
2732003
Endoplasmic reticulum stress causes the activation of sterol regulatory element binding protein-2
SM Colgan, D Tang, GH Werstuck, RC Austin
The international journal of biochemistry & cell biology 39 (10), 1843-1851, 2007
2182007
Association of multiple cellular stress pathways with accelerated atherosclerosis in hyperhomocysteinemic apolipoprotein E-deficient mice
J Zhou, GH Werstuck, S Lhoták, ABL de Koning, SK Sood, GS Hossain, ...
Circulation 110 (2), 207-213, 2004
2172004
Glucosamine-induced endoplasmic reticulum dysfunction is associated with accelerated atherosclerosis in a hyperglycemic mouse model
GH Werstuck, MI Khan, G Femia, AJ Kim, V Tedesco, B Trigatti, Y Shi
Diabetes 55 (1), 93-101, 2006
1822006
Interleukin‐15 contributes to the regulation of murine adipose tissue and human adipocytes
NG Barra, S Reid, R MacKenzie, G Werstuck, BL Trigatti, C Richards, ...
Obesity 18 (8), 1601-1607, 2010
1362010
Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T
DR Beriault, GH Werstuck
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (10), 2293-2301, 2013
1212013
The role of estrogen in insulin resistance: a review of clinical and preclinical data
M De Paoli, A Zakharia, GH Werstuck
The American journal of pathology 191 (9), 1490-1498, 2021
1102021
Effect of leptin on vascular calcification in apolipoprotein E–deficient mice
M Zeadin, M Butcher, G Werstuck, M Khan, CK Yee, SG Shaughnessy
Arteriosclerosis, thrombosis, and vascular biology 29 (12), 2069-2075, 2009
1002009
Hexosamine biosynthesis pathway flux promotes endoplasmic reticulum stress, lipid accumulation, and inflammatory gene expression in hepatic cells
AT Sage, LA Walter, Y Shi, MI Khan, H Kaneto, A Capretta, GH Werstuck
American Journal of Physiology-Endocrinology and Metabolism 298 (3), E499-E511, 2010
992010
Valproate attenuates accelerated atherosclerosis in hyperglycemic apoE-deficient mice: evidence in support of a role for endoplasmic reticulum stress and glycogen synthase …
AJ Bowes, MI Khan, Y Shi, L Robertson, GH Werstuck
The American journal of pathology 174 (1), 330-342, 2009
992009
Molecular mechanisms linking diabetes to the accelerated development of atherosclerosis
MG Zeadin, CI Petlura, GH Werstuck
Canadian journal of diabetes 37 (5), 345-350, 2013
962013
Overexpression of the 78-kDa glucose-regulated protein/immunoglobulin-binding protein (GRP78/BiP) inhibits tissue factor procoagulant activity
LM Watson, AKC Chan, LR Berry, J Li, SK Sood, JG Dickhout, L Xu, ...
Journal of Biological Chemistry 278 (19), 17438-17447, 2003
822003
Evidence supporting a role for endoplasmic reticulum stress in the development of atherosclerosis in a hyperglycaemic mouse model
MI Khan, BA Pichna, Y Shi, AJ Bowes, GH Werstuck
Antioxidants & redox signaling 11 (9), 2289-2298, 2009
782009
GnRH antagonist associates with less adiposity and reduced characteristics of metabolic syndrome and atherosclerosis compared with orchiectomy and GnRH agonist in a preclinical …
SN Hopmans, WCM Duivenvoorden, GH Werstuck, L Klotz, JH Pinthus
Urologic oncology: Seminars and original investigations 32 (8), 1126-1134, 2014
762014
Comprehensive plasma metabolomic analyses of atherosclerotic progression reveal alterations in glycerophospholipid and sphingolipid metabolism in apolipoprotein E-deficient mice
VT Dang, A Huang, LH Zhong, Y Shi, GH Werstuck
Scientific reports 6 (1), 35037, 2016
722016
Metabolic syndrome and acute hyperglycemia are associated with endoplasmic reticulum stress in human mononuclear cells
AT Sage, S Holtby‐Ottenhof, Y Shi, S Damjanovic, AM Sharma, ...
Obesity 20 (4), 748-755, 2012
712012
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