| Spatio-temporal Dynamics of Protein Kinase B/Akt Signaling Revealed by a Genetically Encoded Fluorescent Reporter*♦ MT Kunkel, Q Ni, RY Tsien, J Zhang, AC Newton Journal of Biological Chemistry 280 (7), 5581-5587, 2005 | 267 | 2005 |
| Targeting protein kinase C activity reporter to discrete intracellular regions reveals spatiotemporal differences in agonist-dependent signaling LL Gallegos, MT Kunkel, AC Newton Journal of biological chemistry 281 (41), 30947-30956, 2006 | 217 | 2006 |
| Identification of domains conferring G protein regulation on inward rectifier potassium channels MT Kunkel, EG Peralta Cell 83 (3), 443-449, 1995 | 168 | 1995 |
| AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway GK Carnegie, J Soughayer, FD Smith, BS Pedroja, F Zhang, D Diviani, ... Molecular cell 32 (2), 169-179, 2008 | 152 | 2008 |
| Calcium-dependent regulation of protein kinase D revealed by a genetically encoded kinase activity reporter MT Kunkel, A Toker, RY Tsien, AC Newton Journal of biological chemistry 282 (9), 6733-6742, 2007 | 110 | 2007 |
| Intramolecular conformational changes optimize protein kinase C signaling CE Antal, JD Violin, MT Kunkel, S Skovsø, AC Newton Chemistry & biology 21 (4), 459-469, 2014 | 82 | 2014 |
| Charged amino acids required for signal transduction by the m3 muscarinic acetylcholine receptor. MT Kunkel, EG Peralta The EMBO Journal 12 (10), 3809-3815, 1993 | 80 | 1993 |
| Natural product anacardic acid from cashew nut shells stimulates neutrophil extracellular trap production and bactericidal activity A Hollands, R Corriden, G Gysler, S Dahesh, J Olson, SR Ali, MT Kunkel, ... Journal of Biological Chemistry 291 (27), 13964-13973, 2016 | 75 | 2016 |
| Mutants of a temperature-sensitive two-P domain potassium channel MT Kunkel, DB Johnstone, JH Thomas, L Salkoff Journal of Neuroscience 20 (20), 7517-7524, 2000 | 70 | 2000 |
| Evolution tunes the excitability of individual neurons L Salkoff, A Butler, G Fawcett, M Kunkel, C McArdle, G Paz-y-Mino, ... Neuroscience 103 (4), 853-859, 2001 | 60 | 2001 |
| Protein kinase Cδ-mediated phosphorylation of Connexin43 gap junction channels causes movement within gap junctions followed by vesicle internalization and protein degradation AC Cone, G Cavin, C Ambrosi, H Hakozaki, AX Wu-Zhang, MT Kunkel, ... Journal of Biological Chemistry 289 (13), 8781-8798, 2014 | 58 | 2014 |
| Spatiotemporally distinct protein kinase D activation in adult cardiomyocytes in response to phenylephrine and endothelin J Bossuyt, CW Chang, K Helmstadter, MT Kunkel, AC Newton, ... Journal of Biological Chemistry 286 (38), 33390-33400, 2011 | 56 | 2011 |
| The protein scaffold NHERF-1 controls the amplitude and duration of localized protein kinase D activity MT Kunkel, EL Garcia, T Kajimoto, RA Hall, AC Newton Journal of biological chemistry 284 (36), 24653-24661, 2009 | 54 | 2009 |
| Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors KK Midde, N Aznar, MB Laederich, GS Ma, MT Kunkel, AC Newton, ... Proceedings of the National Academy of Sciences 112 (9), E937-E946, 2015 | 49 | 2015 |
| Active site inhibitors protect protein kinase C from dephosphorylation and stabilize its mature form CM Gould, CE Antal, G Reyes, MT Kunkel, RA Adams, A Ziyar, T Riveros, ... Journal of Biological Chemistry 286 (33), 28922-28930, 2011 | 45 | 2011 |
| Genomic Organization of Nematode 4TM K+ Channelsa ZWEN WANG, MT Kunkel, A Wei, A Butler, L Salkoff Annals of the New York Academy of Sciences 868 (1), 286-303, 1999 | 45 | 1999 |
| Calcium transduces plasma membrane receptor signals to produce diacylglycerol at Golgi membranes MT Kunkel, AC Newton Journal of biological chemistry 285 (30), 22748-22752, 2010 | 42 | 2010 |
| Genetic code expansion and live cell imaging reveal that Thr-308 phosphorylation is irreplaceable and sufficient for Akt1 activity N Balasuriya, MT Kunkel, X Liu, KK Biggar, SSC Li, AC Newton, ... Journal of Biological Chemistry 293 (27), 10744-10756, 2018 | 40 | 2018 |
| Pleckstrin homology domain leucine-rich repeat protein phosphatases set the amplitude of receptor tyrosine kinase output G Reyes, M Niederst, K Cohen-Katsenelson, JD Stender, MT Kunkel, ... Proceedings of the National Academy of Sciences 111 (38), E3957-E3965, 2014 | 30 | 2014 |
| Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus X Zhou, Y Zhong, O Molinar-Inglis, MT Kunkel, M Chen, T Sun, J Zhang, ... Nature communications 11 (1), 6088, 2020 | 27 | 2020 |
