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Derek H. Oakley, M.D., Ph.D.
Derek H. Oakley, M.D., Ph.D.
Instructor in Pathology, Massachusetts General Hospital, Harvard Medical School
Verified email at partners.org
Title
Cited by
Cited by
Year
Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines
C Bock, E Kiskinis, G Verstappen, H Gu, G Boulting, ZD Smith, M Ziller, ...
Cell 144 (3), 439-452, 2011
11412011
A functionally characterized test set of human induced pluripotent stem cells
GL Boulting, E Kiskinis, GF Croft, MW Amoroso, DH Oakley, BJ Wainger, ...
Nature biotechnology 29 (3), 279-286, 2011
5812011
Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1
E Kiskinis, J Sandoe, LA Williams, GL Boulting, R Moccia, BJ Wainger, ...
Cell stem cell 14 (6), 781-795, 2014
4982014
Tau molecular diversity contributes to clinical heterogeneity in Alzheimer’s disease
S Dujardin, C Commins, A Lathuiliere, P Beerepoot, AR Fernandes, ...
Nature medicine 26 (8), 1256-1263, 2020
3152020
Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain
KE Van Der Vos, ER Abels, X Zhang, C Lai, E Carrizosa, D Oakley, ...
Neuro-oncology 18 (1), 58-69, 2015
2972015
Accelerated high-yield generation of limb-innervating motor neurons from human stem cells
MW Amoroso, GF Croft, DJ Williams, S O'Keeffe, MA Carrasco, AR Davis, ...
Journal of Neuroscience 33 (2), 574-586, 2013
2922013
Synaptic tau seeding precedes tau pathology in human Alzheimer's disease brain
SL DeVos, BT Corjuc, DH Oakley, CK Nobuhara, RN Bannon, A Chase, ...
Frontiers in neuroscience 12, 267, 2018
2552018
The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer’s disease
SC Hopp, Y Lin, D Oakley, AD Roe, SL DeVos, D Hanlon, BT Hyman
Journal of neuroinflammation 15, 1-15, 2018
2412018
Pathological correlations of [F‐18]‐AV‐1451 imaging in non‐alzheimer tauopathies
M Marquié, MD Normandin, AC Meltzer, M Siao Tick Chong, NV Andrea, ...
Annals of neurology 81 (1), 117-128, 2017
2052017
SOD1 Suppression with Adeno-Associated Virus and MicroRNA in Familial ALS
C Mueller, JD Berry, DM McKenna-Yasek, G Gernoux, MA Owegi, ...
New England Journal of Medicine 383 (2), 151-158, 2020
1762020
Somatic genomic changes in single Alzheimer’s disease neurons
MB Miller, AY Huang, J Kim, Z Zhou, SL Kirkham, EA Maury, ...
Nature 604 (7907), 714-722, 2022
1122022
Protein prenylation constitutes an endogenous brake on axonal growth
H Li, T Kuwajima, D Oakley, E Nikulina, J Hou, WS Yang, ER Lowry, ...
Cell reports 16 (2), 545-558, 2016
562016
Novel Compound Heterozygous Mutations Expand the Recognized Phenotypes of FARS2-Linked Disease
MA Walker, KP Mohler, KW Hopkins, DH Oakley, DA Sweetser, M Ibba, ...
Journal of child neurology 31 (9), 1127-1137, 2016
472016
Stem cells in the nervous system
AR Maldonado-Soto, DH Oakley, H Wichterle, J Stein, FK Doetsch, ...
American journal of physical medicine & rehabilitation 93 (11), S132-S144, 2014
422014
A 44‐year‐old man with eye, kidney, and brain dysfunction
I Vodopivec, DH Oakley, CA Perugino, N Venna, ET Hedley‐Whyte, ...
Annals of neurology 79 (4), 507-519, 2016
352016
Targeting tau mitigates mitochondrial fragmentation and oxidative stress in amyotrophic lateral sclerosis
T Petrozziello, EA Bordt, AN Mills, SE Kim, E Sapp, BA Devlin, ...
Molecular neurobiology 59 (1), 683-702, 2022
222022
Novel genetic variants in MAPT and alterations in tau phosphorylation in amyotrophic lateral sclerosis post‐mortem motor cortex and cerebrospinal fluid
T Petrozziello, AC Amaral, S Dujardin, SMK Farhan, J Chan, ...
Brain Pathology 32 (2), e13035, 2022
182022
Assessment of cholesterol homeostasis in the living human brain
A Haider, C Zhao, L Wang, Z Xiao, J Rong, X Xia, Z Chen, SK Pfister, ...
Science translational medicine 14 (665), eadc9967, 2022
162022
Plasma biomarkers for diagnosis of Alzheimer's disease and prediction of cognitive decline in individuals with mild cognitive impairment
P Kivisäkk, BC Carlyle, T Sweeney, BA Trombetta, K LaCasse, L El-Mufti, ...
Frontiers in Neurology 14, 1069411, 2023
142023
Segmentation of tau stained Alzheimers brain tissue using convolutional neural networks
A Wurts, DH Oakley, BT Hyman, S Samsi
2020 42nd Annual International Conference of the IEEE Engineering in …, 2020
132020
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