Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival BC Özdemir, T Pentcheva-Hoang, JL Carstens, X Zheng, CC Wu, ... Cancer cell 25 (6), 719-734, 2014 | 2439 | 2014 |
The roles of TGFβ in the tumour microenvironment M Pickup, S Novitskiy, HL Moses Nature Reviews Cancer 13 (11), 788-799, 2013 | 993 | 2013 |
Lipid accumulation and dendritic cell dysfunction in cancer DL Herber, W Cao, Y Nefedova, SV Novitskiy, S Nagaraj, VA Tyurin, ... Nature medicine 16 (8), 880-886, 2010 | 647 | 2010 |
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression H Laklai, YA Miroshnikova, MW Pickup, EA Collisson, GE Kim, AS Barrett, ... Nature medicine 22 (5), 497-505, 2016 | 554 | 2016 |
Adenosine receptors in regulation of dendritic cell differentiation and function SV Novitskiy, S Ryzhov, R Zaynagetdinov, AE Goldstein, Y Huang, ... Blood, The Journal of the American Society of Hematology 112 (5), 1822-1831, 2008 | 457 | 2008 |
Adenosinergic regulation of the expansion and immunosuppressive activity of CD11b+ Gr1+ cells S Ryzhov, SV Novitskiy, AE Goldstein, A Biktasova, MR Blackburn, ... The Journal of Immunology 187 (11), 6120-6129, 2011 | 264 | 2011 |
Distinct roles of VEGFR-1 and VEGFR-2 in the aberrant hematopoiesis associated with elevated levels of VEGF Y Huang, X Chen, MM Dikov, SV Novitskiy, CA Mosse, L Yang, ... Blood, The Journal of the American Society of Hematology 110 (2), 624-631, 2007 | 240 | 2007 |
Bone marrow–derived fibroblasts are a functionally distinct stromal cell population in breast cancer Y Raz, N Cohen, O Shani, RE Bell, SV Novitskiy, L Abramovitz, C Levy, ... Journal of Experimental Medicine 215 (12), 3075-3093, 2018 | 213 | 2018 |
Host A2B adenosine receptors promote carcinoma growth S Ryzhov, SV Novitskiy, DP Carbone, I Biaggioni, R Zaynagetdinov, ... Neoplasia 10 (9), 987-995, 2008 | 183 | 2008 |
TGF-β receptor II loss promotes mammary carcinoma progression by Th17-dependent mechanisms SV Novitskiy, MW Pickup, AE Gorska, P Owens, A Chytil, M Aakre, H Wu, ... Cancer discovery 1 (5), 430-441, 2011 | 156 | 2011 |
Effect of A2B adenosine receptor gene ablation on adenosine-dependent regulation of proinflammatory cytokines S Ryzhov, R Zaynagetdinov, AE Goldstein, SV Novitskiy, MR Blackburn, ... Journal of Pharmacology and Experimental Therapeutics 324 (2), 694-700, 2008 | 143 | 2008 |
Fibroblast-mediated collagen remodeling within the tumor microenvironment facilitates progression of thyroid cancers driven by BrafV600E and Pten loss LA Jolly, S Novitskiy, P Owens, N Massoll, N Cheng, W Fang, HL Moses, ... Cancer research 76 (7), 1804-1813, 2016 | 123 | 2016 |
Role of TGF-β signaling in generation of CD39+ CD73+ myeloid cells in tumors SV Ryzhov, MW Pickup, A Chytil, AE Gorska, Q Zhang, P Owens, ... The Journal of Immunology 193 (6), 3155-3164, 2014 | 121 | 2014 |
Inhibition of BMP signaling suppresses metastasis in mammary cancer P Owens, MW Pickup, SV Novitskiy, JM Giltnane, AE Gorska, CR Hopkins, ... Oncogene 34 (19), 2437-2449, 2015 | 115 | 2015 |
PI3K inhibition reduces mammary tumor growth and facilitates antitumor immunity and anti-PD1 responses J Sai, P Owens, SV Novitskiy, OE Hawkins, AE Vilgelm, J Yang, T Sobolik, ... Clinical Cancer Research 23 (13), 3371-3384, 2017 | 98 | 2017 |
Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators P Owens, MW Pickup, SV Novitskiy, A Chytil, AE Gorska, ME Aakre, ... Proceedings of the National Academy of Sciences 109 (8), 2814-2819, 2012 | 94 | 2012 |
Effect of A2B adenosine receptor gene ablation on proinflammatory adenosine signaling in mast cells S Ryzhov, R Zaynagetdinov, AE Goldstein, SV Novitskiy, MM Dikov, ... The Journal of Immunology 180 (11), 7212-7220, 2008 | 93 | 2008 |
Deletion of TGF-β signaling in myeloid cells enhances their anti-tumorigenic properties SV Novitskiy, MW Pickup, A Chytil, D Polosukhina, P Owens, HL Moses Journal of leukocyte biology 92 (3), 641-651, 2012 | 88 | 2012 |
Switching off CD73: a way to boost the activity of conventional and targeted antineoplastic therapies L Antonioli, SV Novitskiy, KF Sachsenmeier, M Fornai, C Blandizzi, ... Drug discovery today 22 (11), 1686-1696, 2017 | 79 | 2017 |
Epithelial-macrophage interactions determine pulmonary fibrosis susceptibility in Hermansky-Pudlak syndrome LR Young, PM Gulleman, CW Short, H Tanjore, T Sherrill, A Qi, ... JCI insight 1 (17), 2016 | 78 | 2016 |