Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease PR Joshi, NP Wu, VM André, DM Cummings, C Cepeda, JA Joyce, ... Journal of Neuroscience 29 (8), 2414-2427, 2009 | 197 | 2009 |
Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease RK Graham, MA Pouladi, P Joshi, G Lu, Y Deng, NP Wu, BE Figueroa, ... Journal of Neuroscience 29 (7), 2193-2204, 2009 | 139 | 2009 |
A critical window of CAG repeat-length correlates with phenotype severity in the R6/2 mouse model of Huntington's disease DM Cummings, Y Alaghband, MA Hickey, PR Joshi, SC Hong, C Zhu, ... Journal of neurophysiology 107 (2), 677-691, 2012 | 85 | 2012 |
Alpha‐synuclein overexpression in mice alters synaptic communication in the corticostriatal pathway N Wu, PR Joshi, C Cepeda, E Masliah, MS Levine Journal of neuroscience research 88 (8), 1764-1776, 2010 | 83 | 2010 |
Enhanced GABAergic inputs contribute to functional alterations of cholinergic interneurons in the R6/2 mouse model of Huntington’s disease SM Holley, PR Joshi, A Parievsky, L Galvan, JY Chen, YE Fisher, ... Eneuro 2 (1), 2015 | 45 | 2015 |
Identification of critical residues in loop E in the 5-HT3ASR binding site P Venkataraman, SP Venkatachalan, PR Joshi, M Muthalagi, MK Schulte BMC biochemistry 3, 1-11, 2002 | 45 | 2002 |
Interactions of granisetron with an agonist-free 5-HT3A receptor model PR Joshi, A Suryanarayanan, E Hazai, MK Schulte, G Maksay, Z Bikádi Biochemistry 45 (4), 1099-1105, 2006 | 44 | 2006 |
Micromechanical measurement of membrane receptor binding for label-free drug discovery Y Zhang, SP Venkatachalan, H Xu, X Xu, P Joshi, HF Ji, M Schulte Biosensors and Bioelectronics 19 (11), 1473-1478, 2004 | 40 | 2004 |
A vertical flow chamber for Xenopus oocyte electrophysiology and automated drug screening PR Joshi, A Suryanarayanan, MK Schulte Journal of neuroscience methods 132 (1), 69-79, 2004 | 36 | 2004 |
Functional group interactions of a 5-HT3R antagonist P Venkataraman, P Joshi, SP Venkatachalan, M Muthalagi, HS Parihar, ... BMC biochemistry 3, 1-13, 2002 | 26 | 2002 |
The loop C region of the murine 5-HT3A receptor contributes to the differential actions of 5-hydroxytryptamine and m-chlorophenylbiguanide A Suryanarayanan, PR Joshi, Z Bikádi, M Mani, TR Kulkarni, C Gaines, ... Biochemistry 44 (25), 9140-9149, 2005 | 24 | 2005 |
Effects of the pimelic diphenylamide histone deacetylase inhibitor HDACi 4b on the R6/2 and N171-82Q mouse models of huntington’s disease JY Chen, EA Wang, L Galvan, M Huynh, P Joshi, C Cepeda, MS Levine PLoS currents 5, 2013 | 14 | 2013 |
5-HT3R Binding of lerisetron: an interdisciplinary approach to drug–Receptor interactions HS Parihar, A Suryanarayanan, C Ma, P Joshi, P Venkataraman, ... Bioorganic & medicinal chemistry letters 11 (16), 2133-2136, 2001 | 14 | 2001 |
A comprehensive study on the 5-hydroxytryptamine3A receptor binding of agonists serotonin and m-chlorophenylbiguanidine E Hazai, P Joshi, EC Skoviak, A Suryanarayanan, MK Schulte, Z Bikadi Bioorganic & medicinal chemistry 17 (16), 5796-5805, 2009 | 9 | 2009 |
Differential sensitivity of cortical neurons to 4-aminopyridine and rapamycin in diverse forms of pediatric epilepsy C Cepeda, V André, J Hauptman, SP Rao, PR Joshi, JY Chen, ... Neuroscience Meeting Planner, 2010 | 5 | 2010 |
The structural basis of ligand interactions in the 5-HT3 receptor binding site MK Schulte, RA Hill, Z Bikádi, G Maksay, HS Parihar, P Joshi, ... Biological and Biophysical Aspects of Ligand-Gated Ion Channel Receptor …, 2006 | 5 | 2006 |
Structure-function studies of the serotonin type-3 receptor ligand-binding domain PR Joshi University of Alaska Fairbanks, 2005 | 3 | 2005 |
Investigation of amino acids in the loop C region of the mouse 5-HT3A R by alanine scanning mutagenesis A Suryanarayanan, PR Joshi, TR Kulkarni, M Mani, MK Schulte FASEB JOURNAL 18 (4), A227-A227, 2004 | | 2004 |
Novel non-label micromechanical technology for drug screening. HF Ji, HF Ji, YM Yang, H Xu, P Joshi, MK Schulte ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 224, U79-U79, 2002 | | 2002 |
2-substituted N-benzylbenzimidazole analogs as molecular probes to investigate the amino interaction at the 5HT (3) receptor. HS Parihar, JY Han, P Joshi, MK Schulte, KS Kirschbaum ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 222, U674-U675, 2001 | | 2001 |