| NF-κB restricts inflammasome activation via elimination of damaged mitochondria Z Zhong, A Umemura, E Sanchez-Lopez, S Liang, S Shalapour, J Wong, ... Cell 164 (5), 896-910, 2016 | 980 | 2016 |
| Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation SS Iyer, Q He, JR Janczy, EI Elliott, Z Zhong, AK Olivier, JJ Sadler, ... Immunity 39 (2), 311-323, 2013 | 914 | 2013 |
| New mitochondrial DNA synthesis enables NLRP3 inflammasome activation Z Zhong, S Liang, E Sanchez-Lopez, F He, S Shalapour, X Lin, J Wong, ... Nature 560 (7717), 198-203, 2018 | 825 | 2018 |
| Limiting inflammation—the negative regulation of NF-κB and the NLRP3 inflammasome IS Afonina, Z Zhong, M Karin, R Beyaert Nature immunology 18 (8), 861-869, 2017 | 603 | 2017 |
| Autophagy, inflammation, and immunity: a troika governing cancer and its treatment Z Zhong, E Sanchez-Lopez, M Karin Cell 166 (2), 288-298, 2016 | 578 | 2016 |
| Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy S Shalapour, J Font-Burgada, G Di Caro, Z Zhong, E Sanchez-Lopez, ... Nature 521 (7550), 94-98, 2015 | 521 | 2015 |
| ER stress cooperates with hypernutrition to trigger TNF-dependent spontaneous HCC development H Nakagawa, A Umemura, K Taniguchi, J Font-Burgada, D Dhar, H Ogata, ... Cancer cell 26 (3), 331-343, 2014 | 482 | 2014 |
| Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity S Shalapour, XJ Lin, IN Bastian, J Brain, AD Burt, AA Aksenov, ... Nature 551 (7680), 340-345, 2017 | 478 | 2017 |
| p62, upregulated during preneoplasia, induces hepatocellular carcinogenesis by maintaining survival of stressed HCC-initiating cells A Umemura, F He, K Taniguchi, H Nakagawa, S Yamachika, ... Cancer cell 29 (6), 935-948, 2016 | 418 | 2016 |
| TRPM2 links oxidative stress to NLRP3 inflammasome activation Z Zhong, Y Zhai, S Liang, Y Mori, R Han, FS Sutterwala, L Qiao Nature communications 4 (1), 1611, 2013 | 378 | 2013 |
| Interleukin-17 receptor a signaling in transformed enterocytes promotes early colorectal tumorigenesis K Wang, MK Kim, G Di Caro, J Wong, S Shalapour, J Wan, W Zhang, ... Immunity 41 (6), 1052-1063, 2014 | 324 | 2014 |
| Autophagy, NLRP3 inflammasome and auto-inflammatory/immune diseases. Z Zhong, E Sanchez-Lopez, M Karin Clinical and experimental rheumatology 34 (4 Suppl 98), 12-16, 2016 | 174 | 2016 |
| Choline uptake and metabolism modulate macrophage IL-1β and IL-18 production E Sanchez-Lopez, Z Zhong, A Stubelius, SR Sweeney, LM Booshehri, ... Cell metabolism 29 (6), 1350-1362. e7, 2019 | 163 | 2019 |
| Targeting colorectal cancer via its microenvironment by inhibiting IGF-1 receptor-insulin receptor substrate and STAT3 signaling E Sanchez-Lopez, E Flashner-Abramson, S Shalapour, Z Zhong, ... Oncogene 35 (20), 2634-2644, 2016 | 154 | 2016 |
| NADPH oxidase 1 in liver macrophages promotes inflammation and tumor development in mice S Liang, HY Ma, Z Zhong, D Dhar, X Liu, J Xu, Y Koyama, T Nishio, ... Gastroenterology 156 (4), 1156-1172. e6, 2019 | 83 | 2019 |
| Emerging role of mitochondrial DNA as a major driver of inflammation and disease progression F Zhong, S Liang, Z Zhong Trends in immunology 40 (12), 1120-1133, 2019 | 77 | 2019 |
| Porcine reproductive and respiratory syndrome virus activates inflammasomes of porcine alveolar macrophages via its small envelope protein E K Zhang, Q Hou, Z Zhong, X Li, H Chen, W Li, J Wen, L Wang, W Liu, ... Virology 442 (2), 156-162, 2013 | 65 | 2013 |
| Prolonged hypernutrition impairs TREM2-dependent efferocytosis to license chronic liver inflammation and NASH development X Wang, Q He, C Zhou, Y Xu, D Liu, N Fujiwara, N Kubota, A Click, ... Immunity 56 (1), 58-77. e11, 2023 | 48 | 2023 |
| Molecular signatures of long-term hepatocellular carcinoma risk in nonalcoholic fatty liver disease N Fujiwara, N Kubota, E Crouchet, B Koneru, CA Marquez, AK Jajoriya, ... Science translational medicine 14 (650), eabo4474, 2022 | 47 | 2022 |
| NF-κB: A double-edged sword controlling inflammation D Liu, Z Zhong, M Karin Biomedicines 10 (6), 1250, 2022 | 43 | 2022 |
Michael KarinProfessor of Pharmacology and Pathology,UCSD,School of MedicineVerified email at ucsd.edu
