| Polo-like kinase-1 is a target of the DNA damage checkpoint VAJ Smits, R Klompmaker, L Arnaud, G Rijksen, EA Nigg, RH Medema Nature cell biology 2 (9), 672-676, 2000 | 613 | 2000 |
| Checking out the G2/M transition VAJ Smits, RH Medema Biochimica et Biophysica Acta (BBA)-Gene Structure and Expression 1519 (1-2 …, 2001 | 499 | 2001 |
| p21 inhibits Thr161 phosphorylation of Cdc2 to enforce the G2 DNA damage checkpoint VAJ Smits, R Klompmaker, T Vallenius, G Rijksen, TP Mäkelä, ... Journal of Biological Chemistry 275 (39), 30638-30643, 2000 | 299 | 2000 |
| Polo-like kinase-1 controls proteasome-dependent degradation of Claspin during checkpoint recovery I Mamely, MATM van Vugt, VAJ Smits, JI Semple, B Lemmens, A Perrakis, ... Current Biology 16 (19), 1950-1955, 2006 | 270 | 2006 |
| Rapid PIKK-dependent release of Chk1 from chromatin promotes the DNA-damage checkpoint response VAJ Smits, PM Reaper, SP Jackson Current Biology 16 (2), 150-159, 2006 | 239 | 2006 |
| Inhibition of Polo-like kinase-1 by DNA damage occurs in an ATM-or ATR-dependent fashion MATM van Vugt, VAJ Smits, R Klompmaker, RH Medema Journal of Biological Chemistry 276 (45), 41656-41660, 2001 | 225 | 2001 |
| p21waf1 can block cells at two points in the cell cycle, but does not interfere with processive DNA-replication or stress-activated kinases RH Medema, R Klompmaker, VAJ Smits, G Rijksen Oncogene 16 (4), 431-441, 1998 | 222 | 1998 |
| Wee1 controls genomic stability during replication by regulating the Mus81-Eme1 endonuclease R Domínguez-Kelly, Y Martín, S Koundrioukoff, ME Tanenbaum, ... Journal of Cell Biology 194 (4), 567-579, 2011 | 205 | 2011 |
| DNA damage control: regulation and functions of checkpoint kinase 1 VAJ Smits, DA Gillespie The FEBS journal 282 (19), 3681-3692, 2015 | 106 | 2015 |
| USP7 controls Chk1 protein stability by direct deubiquitination I Alonso-de Vega, Y Martín, VA Smits Cell cycle 13 (24), 3921-3926, 2014 | 101 | 2014 |
| Mammalian TIMELESS is involved in period determination and DNA damage-dependent phase advancing of the circadian clock E Engelen, RC Janssens, K Yagita, VAJ Smits, GTJ van der Horst, ... PloS one 8 (2), e56623, 2013 | 92 | 2013 |
| The Nucleocapsid protein triggers the main humoral immune response in COVID-19 patients VAJ Smits, E Hernández-Carralero, MC Paz-Cabrera, E Cabrera, ... Biochemical and biophysical research communications 543, 45-49, 2021 | 91 | 2021 |
| Claspin–checkpoint adaptor and DNA replication factor VAJ Smits, E Cabrera, R Freire, DA Gillespie The FEBS journal 286 (3), 441-455, 2019 | 80 | 2019 |
| HUWE 1 interacts with PCNA to alleviate replication stress KN Choe, CM Nicolae, D Constantin, Y Imamura Kawasawa, ... EMBO reports 17 (6), 874-886, 2016 | 66 | 2016 |
| Mechanisms of ATR-mediated checkpoint signalling VA Smits, DO Warmerdam, Y Martin, R Freire Front Biosci 15, 840-853, 2010 | 53 | 2010 |
| The mineralocorticoid receptor is a constitutive nuclear factor in cardiomyocytes due to hyperactive nuclear localization signals I Hernández-Díaz, T Giraldez, MR Arnau, VAJ Smits, F Jaisser, N Farman, ... Endocrinology 151 (8), 3888-3899, 2010 | 48 | 2010 |
| Dub3 controls DNA damage signalling by direct deubiquitination of H2AX MR Delgado-Díaz, Y Martín, A Berg, R Freire, VAJ Smits Molecular oncology 8 (5), 884-893, 2014 | 47 | 2014 |
| Cleavage and degradation of Claspin during apoptosis by caspases and the proteasome JI Semple, VAJ Smits, JR Fernaud, I Mamely, R Freire Cell Death & Differentiation 14 (8), 1433-1442, 2007 | 47 | 2007 |
| ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage AL Medhurst, DO Warmerdam, I Akerman, EH Verwayen, R Kanaar, ... Journal of cell science 121 (23), 3933-3940, 2008 | 42 | 2008 |
| EDD induces cell cycle arrest by increasing p53 levels VAJ Smits Cell cycle 11 (4), 715-720, 2012 | 36 | 2012 |
