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Peter Sjö
Peter Sjö
Drugs for Neglected Disease initiative
Verified email at dndi.org - Homepage
Title
Cited by
Cited by
Year
The oral protease inhibitor (PF-07321332) protects Syrian hamsters against infection with SARS-CoV-2 variants of concern
R Abdelnabi, CS Foo, D Jochmans, L Vangeel, S De Jonghe, ...
Nature Communications 13 (1), 719, 2022
1082022
Asymmetric dihydroxylation of enynes
KS Jeong, P Sjö, KB Sharpless
Tetrahedron letters 33 (27), 3833-3836, 1992
831992
Explanation for main features of structure–genotoxicity relationships of aromatic amines by theoretical studies of their activation pathways in CYP1A2
I Shamovsky, L Ripa, L Borjesson, C Mee, B Nordén, P Hansen, ...
Journal of the American Chemical Society 133 (40), 16168-16185, 2011
752011
Open Science Discovery of Potent Non-Covalent SARS-CoV-2 Main Protease Inhibitors
COVID Moonshot Consortium, H Achdout, A Aimon, DS Alonzi, R Arbon, ...
BioRxiv, 2020.10. 29.339317, 2020
362020
Neutrophil elastase inhibitors: recent advances in the development of mechanism-based and nonelectrophilic inhibitors
P Sjö
Future Medicinal Chemistry 4 (5), 651-660, 2012
362012
Toward the Design of Molecular Chameleons: Flexible Shielding of an Amide Bond Enhances Macrocycle Cell Permeability
M Tyagi, V Poongavanam, M Lindhagen, A Pettersen, P Sjö, S Schiesser, ...
Organic Letters 20 (18), 5737-5742, 2018
352018
Theoretical studies of chemical reactivity of metabolically activated forms of aromatic amines toward DNA
I Shamovsky, L Ripa, N Blomberg, LA Eriksson, P Hansen, C Mee, ...
Chemical Research in Toxicology 25 (10), 2236-2252, 2012
352012
Pharmaceutically active compounds
H Bergstrand, K Karabelas, P Sjö
US Patent 6,271,231, 2001
352001
Structural basis of nirmatrelvir and ensitrelvir activity against naturally occurring polymorphisms of the SARS-CoV-2 main protease
GD Noske, E de Souza Silva, MO de Godoy, I Dolci, RS Fernandes, ...
Journal of Biological Chemistry 299 (3), 2023
332023
Pyridopyrimidine Derivatives and Their Use as PDE4 Inhibitors
R Austin, RV Bonnert, SF Hunt, G Nikitidis, HJ Sanganee, PO Sjo, ...
US Patent App. 12/293,480, 2009
312009
Mining natural products for macrocycles to drug difficult targets
F Begnini, V Poongavanam, B Over, M Castaldo, S Geschwindner, ...
Journal of Medicinal Chemistry 64 (2), 1054-1072, 2020
302020
Protein kinase inhibitors
K Karabelas, M Lepistö, P Sjö
US Patent 6,346,625, 2002
292002
Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors
ML Boby, D Fearon, M Ferla, M Filep, L Koekemoer, MC Robinson, ...
Science 382 (6671), eabo7201, 2023
212023
Theoretical studies of the mechanism of N-hydroxylation of primary aromatic amines by cytochrome P450 1A2: radicaloid or anionic?
L Ripa, C Mee, P Sjo, I Shamovsky
Chemical Research in Toxicology 27 (2), 265-278, 2014
212014
Toward consensus on correct interpretation of protein binding in plasma and other biological matrices for COVID‐19 therapeutic development
M Boffito, DJ Back, C Flexner, P Sjö, TF Blaschke, PW Horby, D Cattaneo, ...
Clinical Pharmacology & Therapeutics 110 (1), 64-68, 2021
202021
Importance of binding site hydration and flexibility revealed when optimizing a macrocyclic inhibitor of the Keap1–Nrf2 protein–protein interaction
F Begnini, S Geschwindner, P Johansson, L Wissler, RJ Lewis, ...
Journal of medicinal chemistry 65 (4), 3473-3517, 2022
182022
Pharmaceutically active compounds
K Karabelas, M Lepistö, P Sjö
US Patent 6,492,406, 2002
182002
Cyclic Peptide Production Using a Macrocyclase with Enhanced Substrate Promiscuity and Relaxed Recognition Determinants
CN Alexandru-Crivac, C Umeobika, N Leikoski, J Jokela, K Rickaby, P Sjö, ...
Chem. Commun. 53, 10656-10659, 2017
172017
Antiviral and anti-inflammatory activities of fluoxetine in a SARS-CoV-2 infection mouse model
D Péricat, SA Leon-Icaza, M Sanchez Rico, C Mühle, I Zoicas, ...
International Journal of Molecular Sciences 23 (21), 13623, 2022
162022
Susceptibility testing of medically important parasites
A Genetu Bayih, A Debnath, E Mitre, CD Huston, B Laleu, D Leroy, ...
Clinical Microbiology Reviews 30 (3), 647-669, 2017
162017
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