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Christopher Randall
Christopher Randall
Associate Professor of Microbiology, University of Leeds
Verified email at leeds.ac.uk - Homepage
Title
Cited by
Cited by
Year
Silver resistance in Gram-negative bacteria: a dissection of endogenous and exogenous mechanisms
CP Randall, A Gupta, N Jackson, D Busse, AJ O'Neill
Journal of Antimicrobial Chemotherapy 70 (4), 1037-1046, 2015
2702015
The target of daptomycin is absent from Escherichia coli and other Gram-negative pathogens
CP Randall, KR Mariner, I Chopra, AJ O'Neill
Antimicrobial agents and chemotherapy 57 (1), 637-639, 2013
1842013
The silver cation (Ag+): antistaphylococcal activity, mode of action and resistance studies
CP Randall, LB Oyama, JM Bostock, I Chopra, AJ O'Neill
Journal of Antimicrobial Chemotherapy 68 (1), 131-138, 2013
1492013
XF-70 and XF-73, novel antibacterial agents active against slow-growing and non-dividing cultures of Staphylococcus aureus including biofilms
N Ooi, K Miller, C Randall, W Rhys-Williams, W Love, I Chopra
Journal of antimicrobial chemotherapy 65 (1), 72-78, 2009
1172009
In vitro studies indicate a high resistance potential for the lantibiotic nisin in Staphylococcus aureus and define a genetic basis for nisin resistance
KL Blake, CP Randall, AJ O'Neill
Antimicrobial agents and chemotherapy 55 (5), 2362-2368, 2011
1002011
Structure–activity relationships of new cyanothiophene inhibitors of the essential peptidoglycan biosynthesis enzyme MurF
M Hrast, S Turk, I Sosič, D Knez, CP Randall, H Barreteau, ...
European Journal of medicinal chemistry 66, 32-45, 2013
572013
Transient Silencing of Antibiotic Resistance by Mutation Represents a Significant Potential Source of Unanticipated Therapeutic Failure
L Kime, CP Randall, FI Banda, F Coll, J Wright, J Richardson, J Empel, ...
mBio 10 (5), e01755-19, 2019
442019
Impact of exposure of methicillin-resistant Staphylococcus aureus to polyhexanide in vitro and in vivo
A Renzoni, E Von Dach, C Landelle, SM Diene, C Manzano, R Gonzales, ...
Antimicrobial Agents and Chemotherapy 61 (10), e00272-17, 2017
382017
Cryptic silver resistance is prevalent and readily activated in certain Gram-negative pathogens
E Elkrewi, CP Randall, N Ooi, JL Cottell, AJ O’neill
Journal of Antimicrobial Chemotherapy 72 (11), 3043-3046, 2017
382017
Design, synthesis and evaluation of second generation MurF inhibitors based on a cyanothiophene scaffold
M Hrast, M Anderluh, D Knez, CP Randall, H Barreteau, AJ O'Neill, ...
European Journal of Medicinal Chemistry 73, 83-96, 2014
382014
Revisiting unexploited antibiotics in search of new antibacterial drug candidates: the case of γ-actinorhodin
NM Nass, S Farooque, C Hind, ME Wand, CP Randall, JM Sutton, ...
Scientific reports 7 (1), 17419, 2017
282017
6-Arylpyrido[2,3-d]pyrimidines as Novel ATP-Competitive Inhibitors of Bacterial D-Alanine:D-Alanine Ligase
V Škedelj, E Arsovska, T Tomašić, A Kroflič, V Hodnik, M Hrast, ...
Public Library of Science 7 (8), e39922, 2012
262012
Targeting Multiple Aminoacyl-tRNA Synthetases Overcomes the Resistance Liabilities Associated with Antibacterial Inhibitors Acting on a Single Such Enzyme
CP Randall, D Rasina, A Jirgensons, AJ O'Neill
Antimicrobial agents and chemotherapy 60 (10), 6359-6361, 2016
252016
Acquired Nisin Resistance in Staphylococcus aureus Involves Constitutive Activation of an Intrinsic Peptide Antibiotic Detoxification Module
CP Randall, A Gupta, B Utley-Drew, SY Lee, G Morrison-Williams, ...
mSphere 3 (6), e00633-18, 2018
24*2018
N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors
MH Charlton, R Aleksis, A Saint-Leger, A Gupta, E Loza, ...
ACS Medicinal Chemistry Letters 9 (2), 84-88, 2018
182018
A Polymorphism in leuS Confers Reduced Susceptibility to GSK2251052 in a Clinical Isolate of Staphylococcus aureus
A Gupta, C Monteferrante, D Rasina, G Leitis, CP Randall, JH Tomlinson, ...
Antimicrobial Agents and Chemotherapy 60 (5), 3219-3221, 2016
92016
A platform for detecting cross-resistance in antibacterial drug discovery
LH Galarion, M Mohamad, Z Alzeyadi, CP Randall, AJ O’Neill
Journal of Antimicrobial Chemotherapy 76 (6), 1467-1471, 2021
32021
An extensively validated whole-cell biosensor for specific, sensitive and high-throughput detection of antibacterial inhibitors targeting cell-wall biosynthesis
LH Galarion, JK Mitchell, CP Randall, AJ O’Neill
Journal of Antimicrobial Chemotherapy 78 (3), 646-655, 2023
12023
The Silver Cation (Ag+): Antibacterial Mode of Action and Mechanisms of Resistance
CP Randall
University of Leeds (School of Molecular and Cellular Biology, Faculty of …, 2013
12013
Transient silencing of antibiotic resistance by mutation represents a significant potential source of unanticipated therapeutic failure. mBio 10: e01755-19
L Kime, CP Randall, FI Banda, F Coll, J Wright, J Richardson, J Empel, ...
2019
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