Autophagy maintains stemness by preventing senescence L García-Prat, M Martínez-Vicente, E Perdiguero, L Ortet, ... Nature 529 (7584), 37-42, 2016 | 1223 | 2016 |
Geriatric muscle stem cells switch reversible quiescence into senescence P Sousa-Victor, S Gutarra, L García-Prat, J Rodriguez-Ubreva, L Ortet, ... Nature 506 (7488), 316-321, 2014 | 960 | 2014 |
Control of satellite cell function in muscle regeneration and its disruption in ageing P Sousa-Victor, L García-Prat, P Muñoz-Cánoves Nature Reviews Molecular Cell Biology 23 (3), 204-226, 2022 | 182 | 2022 |
Muscle stem cell aging: regulation and rejuvenation P Sousa-Victor, L García-Prat, AL Serrano, E Perdiguero, ... Trends in Endocrinology & Metabolism 26 (6), 287-296, 2015 | 175 | 2015 |
Functional dysregulation of stem cells during aging: a focus on skeletal muscle stem cells L García‐Prat, P Sousa‐Victor, P Muñoz‐Cánoves The FEBS journal 280 (17), 4051-4062, 2013 | 154 | 2013 |
Proteostatic and metabolic control of stemness L García-Prat, P Sousa-Victor, P Muñoz-Cánoves Cell Stem Cell 20 (5), 593-608, 2017 | 118 | 2017 |
FoxO maintains a genuine muscle stem-cell quiescent state until geriatric age L García-Prat, E Perdiguero, S Alonso-Martin, S Dell’Orso, ... Nature cell biology 22 (11), 1307-1318, 2020 | 112 | 2020 |
Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals J Segalés, E Perdiguero, AL Serrano, P Sousa-Victor, L Ortet, M Jardí, ... Nature communications 11 (1), 189, 2020 | 110 | 2020 |
Enhancer Hijacking Drives Oncogenic BCL11B Expression in Lineage-Ambiguous Stem Cell Leukemia LE Montefiori, S Bendig, Z Gu, X Chen, P Pölönen, X Ma, A Murison, ... Cancer discovery 11 (11), 2846-2867, 2021 | 97 | 2021 |
Relapse-fated latent diagnosis subclones in acute B lineage leukemia are drug tolerant and possess distinct metabolic programs SM Dobson, L García-Prat, RJ Vanner, J Wintersinger, E Waanders, Z Gu, ... Cancer discovery 10 (4), 568-587, 2020 | 90 | 2020 |
Sphingolipid modulation activates proteostasis programs to govern human hematopoietic stem cell self-renewal SZ Xie, L Garcia-Prat, V Voisin, R Ferrari, OI Gan, E Wagenblast, ... Cell stem cell 25 (5), 639-653. e7, 2019 | 87 | 2019 |
TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate L García-Prat, KB Kaufmann, F Schneiter, V Voisin, A Murison, J Chen, ... Cell stem cell 28 (10), 1838-1850. e10, 2021 | 81 | 2021 |
Dysfunctional autophagy is a driver of muscle stem cell functional decline with aging L García-Prat, P Muñoz-Cánoves, M Martinez-Vicente Autophagy 12 (3), 612-613, 2016 | 63 | 2016 |
The transition from quiescent to activated states in human hematopoietic stem cells is governed by dynamic 3D genome reorganization N Takayama, A Murison, S Takayanagi, C Arlidge, S Zhou, L Garcia-Prat, ... Cell stem cell 28 (3), 488-501. e10, 2021 | 58 | 2021 |
Mapping the cellular origin and early evolution of leukemia in Down syndrome E Wagenblast, J Araújo, OI Gan, SK Cutting, A Murison, G Krivdova, ... Science 373 (6551), eabf6202, 2021 | 48 | 2021 |
Aging, metabolism and stem cells: Spotlight on muscle stem cells L García-Prat, P Munoz-Canoves Molecular and cellular endocrinology 445, 109-117, 2017 | 40 | 2017 |
Sphingosine-1-phosphate receptor 3 potentiates inflammatory programs in normal and leukemia stem cells to promote differentiation SZ Xie, KB Kaufmann, W Wang, M Chan-Seng-Yue, OI Gan, E Laurenti, ... Blood cancer discovery 2 (1), 32-53, 2021 | 36 | 2021 |
Biological and therapeutic implications of a unique subtype of NPM1 mutated AML AS Mer, EM Heath, SA Madani Tonekaboni, N Dogan-Artun, SK Nair, ... Nature Communications 12 (1), 1054, 2021 | 34 | 2021 |
A latent subset of human hematopoietic stem cells resists regenerative stress to preserve stemness KB Kaufmann, AGX Zeng, E Coyaud, L Garcia-Prat, E Papalexi, ... Nature immunology 22 (6), 723-734, 2021 | 33 | 2021 |
The metabolic enzyme hexokinase 2 localizes to the nucleus in AML and normal haematopoietic stem and progenitor cells to maintain stemness GE Thomas, G Egan, L García-Prat, A Botham, V Voisin, PS Patel, ... Nature cell biology 24 (6), 872-884, 2022 | 31 | 2022 |