Pharmacogenetics, drug-metabolizing enzymes, and clinical practice SJ Gardiner, EJ Begg Pharmacological reviews 58 (3), 521-590, 2006 | 552 | 2006 |
Pharmacogenetic testing for drug metabolizing enzymes: is it happening in practice? SJ Gardiner, EJ Begg Pharmacogenetics and genomics 15 (5), 365-369, 2005 | 119 | 2005 |
Transfer of olanzapine into breast milk, calculation of infant drug dose, and effect on breast-fed infants SJ Gardiner, JH Kristensen, EJ Begg, LP Hackett, DA Wilson, KF Ilett, ... American Journal of Psychiatry 160 (8), 1428-1431, 2003 | 118 | 2003 |
Rapid and simple high-performance liquid chromatographic assay for the determination of metformin in human plasma and breast milk M Zhang, GA Moore, M Lever, SJ Gardiner, CMJ Kirkpatrick, EJ Begg Journal of Chromatography B 766 (1), 175-179, 2002 | 117 | 2002 |
Exposure to thiopurine drugs through breast milk is low based on metabolite concentrations in mother‐infant pairs SJ Gardiner, RB Gearry, RL Roberts, M Zhang, ML Barclay, EJ Begg British journal of clinical pharmacology 62 (4), 453-456, 2006 | 116 | 2006 |
Pharmacoeconomic analyses of azathioprine, methotrexate and prospective pharmacogenetic testing for the management of inflammatory bowel disease VL Priest, EJ Begg, SJ Gardiner, CMA Frampton, RB Gearry, ML Barclay, ... Pharmacoeconomics 24, 767-781, 2006 | 107 | 2006 |
Transfer of metformin into human milk SJ Gardiner, CMJ Kirkpatrick, EJ Begg, M Zhang, MP Moore, DJ Saville Clinical Pharmacology & Therapeutics 73 (1), 71-77, 2003 | 97 | 2003 |
Thiopurine dose in intermediate and normal metabolizers of thiopurine methyltransferase may differ three-fold SJ Gardiner, RB Gearry, EJ Begg, M Zhang, ML Barclay Clinical Gastroenterology and Hepatology 6 (6), 654-660, 2008 | 93 | 2008 |
Transfer of risperidone and 9-hydroxyrisperidone into human milk KF Ilett, LP Hackett, JH Kristensen, KS Vaddadi, SJ Gardiner, EJ Begg Annals of Pharmacotherapy 38 (2), 273-276, 2004 | 92 | 2004 |
Breastfeeding during tacrolimus therapy SJ Gardiner, EJ Begg Obstetrics & Gynecology 107 (2 Part 2), 453-455, 2006 | 74 | 2006 |
Effect of pregnancy on the pharmacokinetics of metformin RCE Hughes, SJ Gardiner, EJ Begg, M Zhang Diabetic Medicine 23 (3), 323-326, 2006 | 73 | 2006 |
The dosing and monitoring of vancomycin: what is the best way forward? PG Drennan, EJ Begg, SJ Gardiner, CMJ Kirkpatrick, ST Chambers International journal of antimicrobial agents 53 (4), 401-407, 2019 | 69 | 2019 |
Development and validation of a stereoselective liquid chromatography–tandem mass spectrometry assay for quantification of S-and R-metoprolol in human plasma BP Jensen, CF Sharp, SJ Gardiner, EJ Begg Journal of Chromatography B 865 (1-2), 48-54, 2008 | 69 | 2008 |
Severe hepatotoxicity with high 6-methylmercaptopurine nucleotide concentrations after thiopurine dose escalation due to low 6-thioguanine nucleotides SJ Gardiner, RB Gearry, MJ Burt, SL Ding, ML Barclay European journal of gastroenterology & hepatology 20 (12), 1238-1242, 2008 | 53 | 2008 |
Two cases of thiopurine methyltransferase (TPMT) deficiency–a lucky save and a near miss with azathioprine SJ Gardiner, RB Gearry, ML Barclay, EJ Begg British journal of clinical pharmacology 62 (4), 473-476, 2006 | 48 | 2006 |
Determination of celecoxib in human plasma and breast milk by high-performance liquid chromatographic assay M Zhang, GA Moore, SJ Gardiner, EJ Begg Journal of Chromatography B 830 (2), 245-248, 2006 | 46 | 2006 |
Allopurinol might improve response to azathioprine and 6‐mercaptopurine by correcting an unfavorable metabolite ratio SJ Gardiner, RB Gearry, MJ Burt, T Chalmers‐Watson, BA Chapman, ... Journal of gastroenterology and hepatology 26 (1), 49-54, 2011 | 45 | 2011 |
CYP2D6 genotype and its relationship with metoprolol dose, concentrations and effect in patients with systolic heart failure CF Sharp, SJ Gardiner, BP Jensen, RL Roberts, RW Troughton, ... The pharmacogenomics journal 9 (3), 175-184, 2009 | 44 | 2009 |
The effect of dihydropyrimidine dehydrogenase deficiency on outcomes with fluorouracil SJ Gardiner, EJ Begg, BA Robinson Adverse drug reactions and toxicological reviews 21, 1-16, 2002 | 42 | 2002 |
Quantification of infant exposure to celecoxib through breast milk SJ Gardiner, MP Doogue, M Zhang, EJ Begg British journal of clinical pharmacology 61 (1), 101-104, 2006 | 37 | 2006 |