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Kuan-lin Huang
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The repertoire of mutational signatures in human cancer
LB Alexandrov, J Kim, NJ Haradhvala, MN Huang, AW Tian Ng, Y Wu, ...
Nature 578 (7793), 94-101, 2020
23382020
Proteogenomics connects somatic mutations to signalling in breast cancer
P Mertins, DR Mani, KV Ruggles, MA Gillette, KR Clauser, P Wang, ...
Nature 534 (7605), 55-62, 2016
15262016
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
14842020
The evolutionary history of 2,658 cancers
M Gerstung, C Jolly, I Leshchiner, SC Dentro, S Gonzalez, D Rosebrock, ...
Nature 578 (7793), 122-128, 2020
8352020
Pathogenic germline variants in 10,389 adult cancers
K Huang, RJ Mashl, Y Wu, DI Ritter, J Wang, C Oh, M Paczkowska, ...
Cell 173 (2), 355-370. e14, 2018
6932018
Patterns of somatic structural variation in human cancer genomes
Y Li, ND Roberts, JA Wala, O Shapira, SE Schumacher, K Kumar, ...
Nature 578 (7793), 112-121, 2020
6762020
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
I Cortés-Ciriano, JJK Lee, R Xi, D Jain, YL Jung, L Yang, D Gordenin, ...
Nature genetics 52 (3), 331-341, 2020
5262020
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ...
Nature 578 (7793), 102-111, 2020
4972020
Perspective on oncogenic processes at the end of the beginning of cancer genomics
L Ding, MH Bailey, E Porta-Pardo, V Thorsson, A Colaprico, D Bertrand, ...
Cell 173 (2), 305-320. e10, 2018
3492018
A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease
K Huang, E Marcora, AA Pimenova, AFD Narzo, M Kapoor, SC Jin, ...
Nature Neuroscience, 2017
3422017
Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture
Q Zhang, J Sidorenko, B Couvy-Duchesne, RE Marioni, MJ Wright, ...
Nature communications 11 (1), 4799, 2020
3242020
The landscape of viral associations in human cancers
M Zapatka, I Borozan, DS Brewer, M Iskar, A Grundhoff, M Alawi, N Desai, ...
Nature genetics 52 (3), 320-330, 2020
3182020
Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
B Rodriguez-Martin, EG Alvarez, A Baez-Ortega, J Zamora, F Supek, ...
Nature genetics 52 (3), 306-319, 2020
3092020
Patterns and functional implications of rare germline variants across 12 cancer types
C Lu, M Xie, MC Wendl, J Wang, MD McLellan, MDM Leiserson, K Huang, ...
Nature communications 6 (1), 10086, 2015
2972015
Genomic basis for RNA alterations in cancer
PCAWG Transcriptome Core Group Calabrese Claudia 2 Davidson Natalie R. 3 4 5 ...
Nature 578 (7793), 129-136, 2020
2712020
Genome-wide association study identifies four novel loci associated with Alzheimer’s endophenotypes and disease modifiers
Y Deming, Z Li, M Kapoor, O Harari, JL Del-Aguila, K Black, D Carrell, ...
Acta neuropathologica 133 (5), 839-856, 2017
1982017
Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer
KC Akdemir, VT Le, S Chandran, Y Li, RG Verhaak, R Beroukhim, ...
Nature genetics 52 (3), 294-305, 2020
1922020
Comprehensive analysis of genetic ancestry and its molecular correlates in cancer
J Carrot-Zhang, N Chambwe, JS Damrauer, TA Knijnenburg, ...
Cancer Cell 37 (5), 639-654. e6, 2020
1732020
A deep learning system accurately classifies primary and metastatic cancers using passenger mutation patterns
W Jiao, G Atwal, P Polak, R Karlic, E Cuppen, A Danyi, J de Ridder, ...
Nature communications 11 (1), 728, 2020
1692020
Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis
J Carlevaro-Fita, A Lanzós, L Feuerbach, C Hong, D Mas-Ponte, ...
Communications biology 3 (1), 56, 2020
1592020
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