| BET bromodomain inhibitors MP Schwalm, S Knapp Current opinion in chemical biology 68, 102148, 2022 | 53 | 2022 |
| PROTAC degraders as chemical probes for studying target biology and target validation V Němec, MP Schwalm, S Müller, S Knapp Chemical Society Reviews 51 (18), 7971-7993, 2022 | 32 | 2022 |
| Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization MP Schwalm, A Krämer, A Dölle, J Weckesser, X Yu, J Jin, K Saxena, ... Cell chemical biology 30 (7), 753-765. e8, 2023 | 20 | 2023 |
| Development of the first covalent monopolar spindle kinase 1 (MPS1/TTK) Inhibitor RA M. Serafim, A da Silva Santiago, MP Schwalm, Z Hu, CV Dos Reis, ... Journal of Medicinal Chemistry 65 (4), 3173-3192, 2022 | 15 | 2022 |
| A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins MP Schwalm, L Berger, M Meuter, J Vasta, C Corona, S Röhm, B Berger, ... Frontiers in cell and developmental biology 10, 2022 | 12 | 2022 |
| Crystal structure and inhibitor identifications reveal targeting opportunity for the atypical MAPK kinase ERK3 M Schröder, P Filippakopoulos, MP Schwalm, CA Ferrer, DH Drewry, ... International journal of molecular sciences 21 (21), 7953, 2020 | 11 | 2020 |
| Discovery of a potent and highly isoform-selective inhibitor of the neglected ribosomal protein S6 kinase beta 2 (S6K2) S Gerstenecker, L Haarer, M Schröder, M Kudolo, MP Schwalm, V Wydra, ... Cancers 13 (20), 5133, 2021 | 10 | 2021 |
| A chemical probe to modulate human GID4 Pro/N-degron interactions DDG Owens, MER Maitland, AK Yazdi, X Song, MP Schwalm, ... bioRxiv, 2023.01. 17.524225, 2023 | 6 | 2023 |
| Development of novel urea-based ATM kinase inhibitors with subnanomolar cellular potency and high kinome selectivity T Dimitrov, C Anli, AA Moschopoulou, T Kronenberger, M Kudolo, ... European Journal of Medicinal Chemistry 235, 114234, 2022 | 6 | 2022 |
| Toward effective Atg8‐based ATTECs: Approaches and perspectives MP Schwalm, S Knapp, VV Rogov Journal of Cellular Biochemistry, 2023 | 4 | 2023 |
| Development of potent dual BET/HDAC inhibitors via pharmacophore merging and structure-guided optimization N Bauer, DI Balourdas, JR Schneider, X Zhang, LM Berger, BT Berger, ... ACS Chemical Biology, 2024 | 2 | 2024 |
| Expanding the ligand spaces for E3 ligases for the design of protein degraders RSZ Saleem, MP Schwalm, S Knapp Bioorganic & medicinal chemistry, 117718, 2024 | 1 | 2024 |
| Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on SNAr Electrophiles M Schwarz, M Kurkunov, F Wittlinger, R Rudalska, G Wang, MP Schwalm, ... Journal of Medicinal Chemistry, 2024 | 1 | 2024 |
| Targeting LC3/GABARAP for degrader development and autophagy modulation MP Schwalm, J Dopfer, A Kumar, FA Greco, N Bauer, F Loehr, J Heering, ... bioRxiv, 2023.10. 05.560930, 2023 | 1 | 2023 |
| Thalidomide derivatives degrade BCL-2 by reprogramming the binding surface of CRBN J Wang, M Heinz, K Han, VJ Shah, S Hasselbeck, MP Schwalm, ... Cell Reports Physical Science, 2024 | | 2024 |
| Luciferase-and HaloTag-based reporter assays to measure small-molecule-induced degradation pathway in living cells MP Schwalm, K Saxena, S Müller, S Knapp Nature Protocols, 1-41, 2024 | | 2024 |
| tracerDB: A crowdsourced fluorescent tracer database for target engagement analysis M Schwalm, J Dopfer, J Vasta, S Muller, S Knapp, M Robers | | 2024 |
| High throughput screening for LC3/GABARAP binders utilizing fluorescence polarization assay MP Schwalm, J Dopfer, S Knapp, VV Rogov arXiv preprint arXiv:2401.04453, 2024 | | 2024 |
| Development of Highly Potent and Selective FGFR4 Inhibitors Based on SNAr Electrophiles M Schwarz, M Kurkunov, F Wittlinger, R Rudalska, G Wang, MP Schwalm, ... | | 2024 |
| Thermodynamic Characterization of LC3/GABARAP Ligands by Isothermal Titration Calorimetry J Dopfer, MP Schwalm, S Knapp, VV Rogov bioRxiv, 2024.01. 08.574610, 2024 | | 2024 |
Stefan KnappUniversity of FrankfurtVerified email at pharmchem.uni-frankfurt.de
