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Mark Manzano
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Downstream of mutant KRAS, the transcription regulator YAP is essential for neoplastic progression to pancreatic ductal adenocarcinoma
W Zhang, N Nandakumar, Y Shi, M Manzano, A Smith, G Graham, ...
Science signaling 7 (324), ra42-ra42, 2014
3852014
Unambiguous identification of miRNA: target site interactions by different types of ligation reactions
S Grosswendt, A Filipchyk, M Manzano, F Klironomos, M Schilling, ...
Molecular cell 54 (6), 1042-1054, 2014
3192014
Amodiaquine, an antimalarial drug, inhibits dengue virus type 2 replication and infectivity
S Boonyasuppayakorn, ED Reichert, M Manzano, K Nagarajan, ...
Antiviral research 106, 125-134, 2014
1192014
Identification of cis-acting elements in the 3′-untranslated region of the dengue virus type 2 RNA that modulate translation and replication
M Manzano, ED Reichert, S Polo, B Falgout, W Kasprzak, BA Shapiro, ...
Journal of Biological Chemistry 286 (25), 22521-22534, 2011
1092011
Gene essentiality landscape and druggable oncogenic dependencies in herpesviral primary effusion lymphoma
M Manzano, A Patil, A Waldrop, SS Dave, A Behdad, E Gottwein
Nature communications 9 (1), 3263, 2018
532018
Kaposi's sarcoma-associated herpesvirus encodes a mimic of cellular miR-23
M Manzano, P Shamulailatpam, AN Raja, E Gottwein
Journal of virology 87 (21), 11821-11830, 2013
422013
CK1α and IRF4 are essential and independent effectors of immunomodulatory drugs in primary effusion lymphoma
A Patil, M Manzano, E Gottwein
Blood, The Journal of the American Society of Hematology 132 (6), 577-586, 2018
402018
Divergent target recognition by coexpressed 5′-isomiRs of miR-142-3p and selective viral mimicry
M Manzano, E Forte, AN Raja, MJ Schipma, E Gottwein
Rna 21 (9), 1606-1620, 2015
402015
MicroRNA-mediated transformation by the Kaposi's sarcoma-associated herpesvirus Kaposin locus
E Forte, AN Raja, P Shamulailatpam, M Manzano, MJ Schipma, JL Casey, ...
Journal of virology 89 (4), 2333-2341, 2015
382015
High-throughput screening for the identification of small-molecule inhibitors of the flaviviral protease
A Balasubramanian, M Manzano, T Teramoto, R Pilankatta, ...
Antiviral research 134, 6-16, 2016
342016
Construction of a dengue virus type 4 reporter replicon and analysis of temperature-sensitive mutations in non-structural proteins 3 and 5
SL Alcaraz-Estrada, MIM Manzano, RM Del Angel, R Levis, ...
Journal of general virology 91 (11), 2713-2718, 2010
322010
Genome-wide CRISPR screens reveal genetic mediators of cereblon modulator toxicity in primary effusion lymphoma
A Patil, M Manzano, E Gottwein
Blood Advances 3 (14), 2105-2117, 2019
252019
The oncogenic Kaposi’s sarcoma-associated herpesvirus encodes a mimic of the tumor-suppressive miR-15/16 miRNA family
K Morrison, M Manzano, K Chung, MJ Schipma, ET Bartom, E Gottwein
Cell reports 29 (10), 2961-2969. e6, 2019
172019
Gamma interferon-inducible lysosomal thioreductase (GILT) ablation renders mouse fibroblasts sensitive to dengue virus replication
T Teramoto, H Chiang, R Takhampunya, M Manzano, R Padmanabhan, ...
Virology 441 (2), 146-151, 2013
172013
Kaposi’s sarcoma-associated herpesvirus drives a super-enhancer-mediated survival gene expression program in primary effusion lymphoma
M Manzano, T Günther, H Ju, J Nicholas, ET Bartom, A Grundhoff, ...
Mbio 11 (4), 10.1128/mbio. 01457-20, 2020
152020
Small molecule inhibitor discovery for dengue virus protease using high-throughput screening
M Manzano, J Padia, R Padmanabhan
Dengue: Methods and Protocols, 331-344, 2014
72014
CRISPR screens identify novel regulators of cFLIP dependency and ligand-independent, TRAIL-R1-mediated cell death
N Kuehnle, SM Osborne, Z Liang, M Manzano, E Gottwein
Cell Death & Differentiation 30 (5), 1221-1234, 2023
22023
Flavivirus protease inhibitors
R Padmanabhan, T Teramoto, M Manzano
US Patent 10,471,082, 2019
22019
Expression Ratios of the Antiapoptotic BCL2 Family Members Dictate the Selective Addiction of Kaposi’s Sarcoma-Associated Herpesvirus-Transformed Primary Effusion Lymphoma Cell …
D Dunham, P Viswanathan, J Gill, M Manzano
Journal of Virology 96 (23), e01360-22, 2022
12022
Suppression of TRIP13 Induces Metabolic Changes and Potentiates Ferroptosis in Multiple Myeloma
Y Cheng, F Sun, W Guo, H Xu, P Viswanathan, M Manzano, E Siegel, ...
Blood 142, 3309, 2023
2023
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