| Therapeutically effective antibodies against amyloid-β peptide target amyloid-β residues 4–10 and inhibit cytotoxicity and fibrillogenesis J McLaurin, R Cecal, ME Kierstead, X Tian, AL Phinney, M Manea, ... Nature medicine 8 (11), 1263-1269, 2002 | 567 | 2002 |
| Dietary restriction reduces insulin-like growth factor I levels, which modulates apoptosis, cell proliferation, and tumor progression in p53-deficient mice SE Dunn, FW Kari, J French, JR Leininger, G Travlos, R Wilson, JC Barrett Cancer research 57 (21), 4667-4672, 1997 | 544 | 1997 |
| Identifying chemical carcinogens and assessing potential risk in short-term bioassays using transgenic mouse models. RW Tennant, JE French, JW Spalding Environmental health perspectives 103 (10), 942-950, 1995 | 296 | 1995 |
| Analysis of genetic instability during mammary tumor progression using a novel selection-based assay for in vivo mutations in a bacteriophage lambda transgene target. JL Jakubczak, G Merlino, JE French, WJ Muller, B Paul, S Adhya, ... Proceedings of the National Academy of Sciences 93 (17), 9073-9078, 1996 | 240 | 1996 |
| Evaluation of transgenic mouse bioassays for identifying carcinogens and noncarcinogens RW Tennant, J Spalding, JE French Mutation Research/Reviews in Genetic Toxicology 365 (1-3), 119-127, 1996 | 164 | 1996 |
| The role of transgenic mouse models in carcinogen identification. JB Pritchard, JE French, BJ Davis, JK Haseman Environmental health perspectives 111 (4), 444-454, 2003 | 156 | 2003 |
| P53+/-hemizygous knockout mouse: overview of available data RD Storer, JE French, J Haseman, G Hajian, EK Legrand, GG Long, ... Toxicologic pathology 29 (1_suppl), 30-50, 2001 | 120 | 2001 |
| Diversity outbred mice identify population-based exposure thresholds and genetic factors that influence benzene-induced genotoxicity JE French, DM Gatti, DL Morgan, GE Kissling, KR Shockley, GA Knudsen, ... Environmental health perspectives 123 (3), 237-245, 2015 | 117 | 2015 |
| The growth hormone: insulin-like growth factor 1 axis is a mediator of diet restriction-induced inhibition of mononuclear cell leukemia in Fischer rats SD Hursting, BR Switzer, JE French, FW Kari Cancer research 53 (12), 2750-2757, 1993 | 113 | 1993 |
| Roles for insulin-like growth factor-1 in mediating the anti-carcinogenic effects of caloric restriction. FW Kari, SE Dunn, JE French, JC Barrett The journal of nutrition, health & aging 3 (2), 92-101, 1999 | 112 | 1999 |
| Is p53 haploinsufficient for tumor suppression? Implications for the p53+/-mouse model in carcinogenicity testing S Venkatachalam, SD Tyner, CR Pickering, S Boley, L Recio, JE French, ... Toxicologic pathology 29 (1_suppl), 147-154, 2001 | 106 | 2001 |
| Responses of Transgenic Mouse Lines p53+/− and Tg•AC to Agents Tested in Conventional Carcinogenicity Bioassays JW Spalding, JE French, S Stasiewicz, M Furedi-Machacek, F Conner, ... Toxicological Sciences 53 (2), 213-223, 2000 | 97 | 2000 |
| Evaluation of tissue disposition, myelopoietic, and immunologic responses in mice after long‐term exposure to nickel sulfate in the drinking water MP Dieter, CW Jameson, AN Tucker, MI Luster, JE French, HL Hong, ... Journal of Toxicology and Environmental Health, Part A Current Issues 24 (3 …, 1988 | 95 | 1988 |
| The utility of genetically modified mouse assays for identifying human carcinogens: a basic understanding and path forward J MacDonald, JE French, RJ Gerson, J Goodman, T Inoue, A Jacobs, ... Toxicological Sciences 77 (2), 188-194, 2004 | 89 | 2004 |
| Transponder-induced sarcoma in the heterozygous p53+/-mouse KT Blanchard, C Barthel, JE French, HE Holden, R Moretz, FD Pack, ... Toxicologic pathology 27 (5), 519-527, 1999 | 88 | 1999 |
| Study design and sample sizes for a lacl transgenic mouse mutation assay WW Piegorsch, BH Margolin, MD Shelby, A Johnson, JE French, ... Environmental and molecular mutagenesis 25 (3), 231-245, 1995 | 85 | 1995 |
| Phenolphthalein induces thymic lymphomas accompanied by loss of the p53 wild type allele in heterozygous p53-deficient (±) mice JK Dunnick, JF Hardisty, RA Herbert, JC Seely, EM Furedi-Machacek, ... Toxicologic pathology 25 (6), 533-540, 1997 | 78 | 1997 |
| p53 Heterozygosity Alters the mRNA Expression of p53 Target Genes in the Bone Marrow in Response to Inhaled Benzene SE Boley, VA Wong, JE French, L Recio Toxicological Sciences 66 (2), 209-215, 2002 | 76 | 2002 |
| A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2 JP Didion, AP Morgan, AMF Clayshulte, RC Mcmullan, L Yadgary, ... PLoS Genetics 11 (2), e1004850, 2015 | 73 | 2015 |
| Loss of heterozygosity frequency at the Trp53 locus in p53-deficient (+/–) mouse tumors is carcinogen-and tissue-dependent JE French, GD Lacks, C Trempus, JK Dunnick, J Foley, J Mahler, RR Tice, ... Carcinogenesis 22 (1), 99-106, 2001 | 73 | 2001 |
