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Umakant Sahu
Umakant Sahu
Postdoctoral research associate
Verified email at northwestern.edu
Title
Cited by
Cited by
Year
Cancer cells tune the signaling pathways to empower de novo synthesis of nucleotides
E Villa, ES Ali, U Sahu, I Ben-Sahra
Cancers 11 (5), 688, 2019
2082019
mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
E Villa, U Sahu, BP O’Hara, ES Ali, KA Helmin, JM Asara, P Gao, ...
Molecular cell 81 (10), 2076-2093. e9, 2021
932021
Trm1p, a Zn (II) 2Cys6-type transcription factor, is essential for the transcriptional activation of genes of methanol utilization pathway, in Pichia pastoris
U Sahu, KK Rao, PN Rangarajan
Biochemical and Biophysical Research Communications 451 (1), 158-164, 2014
512014
ERK2 phosphorylates PFAS to mediate posttranslational control of de novo purine synthesis
ES Ali, U Sahu, E Villa, BP O’Hara, P Gao, C Beaudet, AW Wood, ...
Molecular cell 78 (6), 1178-1191. e6, 2020
472020
Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway
MH Soflaee, R Kesavan, U Sahu, A Tasdogan, E Villa, Z Djabari, F Cai, ...
Nature communications 13 (1), 2698, 2022
302022
Regulation of acetate metabolism and acetyl Co-A synthetase 1 (ACS1) expression by methanol expression regulator 1 (Mxr1p) in the methylotrophic yeast Pichia pastoris
U Sahu, PN Rangarajan
Journal of Biological Chemistry 291 (7), 3648-3657, 2016
212016
Methanol expression regulator 1 (Mxr1p) is essential for the utilization of amino acids as the sole source of carbon by the methylotrophic yeast, Pichia pastoris
U Sahu, PN Rangarajan
Journal of Biological Chemistry 291 (39), 20588-20601, 2016
182016
NOTCH1-driven UBR7 stimulates nucleotide biosynthesis to promote T cell acute lymphoblastic leukemia
S Srivastava, U Sahu, Y Zhou, AK Hogan, KM Sathyan, J Bodner, ...
Science Advances 7 (5), eabc9781, 2021
132021
Methionine synthase is localized to the nucleus in Pichia pastoris and Candida albicans and to the cytoplasm in Saccharomyces cerevisiae
U Sahu, VKH Rajendra, SS Kapnoor, R Bhagavat, N Chandra, ...
Journal of Biological Chemistry 292 (36), 14730-14746, 2017
122017
Characterization of the transactivation and nuclear localization functions of Pichia pastoris zinc finger transcription factor Mxr1p
A Gupta, KK Rao, U Sahu, PN Rangarajan
Journal of Biological Chemistry 297 (4), 2021
52021
GATOR2 rings GATOR1 to speak to mTORC1
U Sahu, I Ben-Sahra
Molecular Cell 83 (1), 6-8, 2023
32023
Function and regulation of an aldehyde dehydrogenase essential for ethanol and methanol metabolism of the yeast, Komagataella phaffii
KK Rao, U Sahu, PN Rangarajan
bioRxiv, 2020.06. 14.151365, 2020
12020
Pyrimidines maintain mitochondrial pyruvate oxidation to support de novo lipogenesis.
U Sahu, E Villa, CR Reczek, Z Zhao, BP O’Hara, MD Torno, R Mishra, ...
Science 383 (6690), 1484-1492, 2024
2024
Exploiting De Novo Serine Synthesis as a Metabolic Vulnerability to Overcome Sunitinib Resistance in Advanced Renal Cell Carcinoma
M Teisseire, U Sahu, J Parola, MC Tsai, V Vial, J Durivault, R Grepin, ...
bioRxiv, 2024.03. 22.586287, 2024
2024
The cell cycle loops UTP around CAD
U Sahu, I Ben-Sahra
Nature Metabolism 5 (2), 199-200, 2023
2023
Mxr1p is a Global Regulator of Multiple Metabolic Pathways in the Methylotrophic Yeast Pichia Pastoris
U Sahu
2018
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Articles 1–16