| Rapid desiccation hardening changes the cuticular hydrocarbon profile of Drosophila melanogaster JR Stinziano, RJ Sové, HD Rundle, BJ Sinclair Comparative Biochemistry and Physiology Part A: Molecular & Integrative …, 2015 | 74 | 2015 |
| Conducting a virtual clinical trial in HER2-negative breast cancer using a quantitative systems pharmacology model with an epigenetic modulator and immune checkpoint inhibitors H Wang, RJ Sové, M Jafarnejad, S Rahmeh, EM Jaffee, V Stearns, ... Frontiers in Bioengineering and Biotechnology 8, 141, 2020 | 41 | 2020 |
| A mechanistic integrative computational model of macrophage polarization: Implications in human pathophysiology C Zhao, AC Mirando, RJ Sové, TX Medeiros, BH Annex, AS Popel PLoS computational biology 15 (11), e1007468, 2019 | 40 | 2019 |
| Quantitative systems pharmacology model predictions for efficacy of atezolizumab and nab-paclitaxel in triple-negative breast cancer H Wang, H Ma, RJ Sové, LA Emens, AS Popel Journal for immunotherapy of cancer 9 (2), 2021 | 37 | 2021 |
| Combination therapy with T cell engager and PD-L1 blockade enhances the antitumor potency of T cells as predicted by a QSP model H Ma, H Wang, RJ Sové, J Wang, C Giragossian, AS Popel Journal for immunotherapy of cancer 8 (2), 2020 | 36 | 2020 |
| QSP‐IO: a quantitative systems pharmacology toolbox for mechanistic multiscale modeling for Immuno‐oncology applications RJ Sové, M Jafarnejad, C Zhao, H Wang, H Ma, AS Popel CPT: pharmacometrics & systems pharmacology 9 (9), 484-497, 2020 | 35 | 2020 |
| A data-driven computational model enables integrative and mechanistic characterization of dynamic macrophage polarization C Zhao, TX Medeiros, RJ Sové, BH Annex, AS Popel Iscience 24 (2), 2021 | 28 | 2021 |
| A quantitative systems pharmacology model of T cell engager applied to solid tumor H Ma, H Wang, RJ Sove, M Jafarnejad, CH Tsai, J Wang, C Giragossian, ... The AAPS Journal 22, 1-16, 2020 | 27 | 2020 |
| Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model A Ruiz-Martinez, C Gong, H Wang, RJ Sové, H Mi, H Kimko, AS Popel PLoS computational biology 18 (7), e1010254, 2022 | 22 | 2022 |
| Virtual clinical trials of anti-PD-1 and anti-CTLA-4 immunotherapy in advanced hepatocellular carcinoma using a quantitative systems pharmacology model RJ Sové, BK Verma, H Wang, WJ Ho, M Yarchoan, AS Popel Journal for immunotherapy of cancer 10 (11), 2022 | 21 | 2022 |
| Mechanistically detailed systems biology modeling of the HGF/Met pathway in hepatocellular carcinoma M Jafarnejad, RJ Sové, L Danilova, AC Mirando, Y Zhang, M Yarchoan, ... NPJ systems biology and applications 5 (1), 29, 2019 | 19 | 2019 |
| A computational model of the effect of capillary density variability on oxygen transport, glucose uptake, and insulin sensitivity in prediabetes RJ Sové, D Goldman, GM Fraser Microcirculation 24 (2), e12342, 2017 | 15 | 2017 |
| A computational model of a microfluidic device to measure the dynamics of oxygen-dependent ATP release from erythrocytes RJ Sove, N Ghonaim, D Goldman, CG Ellis PLoS One 8 (11), e81537, 2013 | 11 | 2013 |
| Localized oxygen exchange platform for intravital video microscopy investigations of microvascular oxygen regulation RJ Sové, S Milkovich, HN Nikolov, DW Holdsworth, CG Ellis, GM Fraser Frontiers in Physiology 12, 654928, 2021 | 8 | 2021 |
| Finite element model of oxygen transport for the design of geometrically complex microfluidic devices used in biological studies RJ Sové, GM Fraser, D Goldman, CG Ellis PloS one 11 (11), e0166289, 2016 | 8 | 2016 |
| Spectroscopy detects skeletal muscle microvascular dysfunction during onset of sepsis in a rat fecal peritonitis model PM Kowalewska, JE Kowalewski, SL Milkovich, RJ Sové, L Wang, ... Scientific Reports 12 (1), 6339, 2022 | 7 | 2022 |
| Optical method to determine in vivo capillary hematocrit, hemoglobin concentration, and 3‐D network geometry in skeletal muscle JR Christie, I Kong, L Mawdsley, S Milkovich, A Doornekamp, J Baek, ... Microcirculation 29 (6-7), e12751, 2022 | 1 | 2022 |
| Development and validation of a novel microfluidic device for the manipulation of skeletal muscle microvascular blood flow in vivo GM Russell McEvoy, H Shogan, RJ Sové, GM Fraser Microcirculation 28 (5), e12698, 2021 | 1 | 2021 |
| IN SILICO VIRTUAL CLINICAL TRIALS OF ATEZOLIZUMAB AND NAB-PACLITAXEL IN ADVANCED TRIPLE-NEGATIVE BREAST CANCER. H Wang, H Ma, R Sove, L Emens, A Popel CLINICAL PHARMACOLOGY & THERAPEUTICS 109, S23-S23, 2021 | | 2021 |
| Correction: Quantitative systems pharmacology model predictions for efficacy of atezolizumab and nab-paclitaxel in triple-negative breast cancer H Wang, H Ma, RJ Sové J Immunother 9, e002100corr1, 2021 | | 2021 |
