Single-molecule visualization of fast polymerase turnover in the bacterial replisome JS Lewis, LM Spenkelink, S Jergic, EA Wood, E Monachino, NP Horan, ... Elife 6, e23932, 2017 | 121 | 2017 |
Tunability of DNA polymerase stability during eukaryotic DNA replication JS Lewis, LM Spenkelink, GD Schauer, O Yurieva, SH Mueller, ... Molecular cell 77 (1), 17-25. e5, 2020 | 79 | 2020 |
Single-molecule visualization of Saccharomyces cerevisiae leading-strand synthesis reveals dynamic interaction between MTC and the replisome JS Lewis, LM Spenkelink, GD Schauer, FR Hill, RE Georgescu, ... Proceedings of the National Academy of Sciences 114 (40), 10630-10635, 2017 | 65 | 2017 |
Watching cellular machinery in action, one molecule at a time E Monachino, LM Spenkelink, AM van Oijen Journal of Cell Biology 216 (1), 41-51, 2017 | 53 | 2017 |
Recycling of single-stranded DNA-binding protein by the bacterial replisome LM Spenkelink, JS Lewis, S Jergic, ZQ Xu, A Robinson, NE Dixon, ... Nucleic acids research 47 (8), 4111-4123, 2019 | 52 | 2019 |
Replisome bypass of a protein-based R-loop block by Pif1 GD Schauer, LM Spenkelink, JS Lewis, O Yurieva, SH Mueller, ... Proceedings of the National Academy of Sciences 117 (48), 30354-30361, 2020 | 37 | 2020 |
Quantification of ligand density and stoichiometry on the surface of liposomes using single-molecule fluorescence imaging L Belfiore, LM Spenkelink, M Ranson, AM van Oijen, KL Vine Journal of controlled release 278, 80-86, 2018 | 33 | 2018 |
Single-molecule imaging at high fluorophore concentrations by local activation of dye HJ Geertsema, AC Schulte, LM Spenkelink, WJ McGrath, SR Morrone, ... Biophysical journal 108 (4), 949-956, 2015 | 24 | 2015 |
When proteins play tag: the dynamic nature of the replisome SH Mueller, LM Spenkelink, AM van Oijen Biophysical reviews 11 (4), 641-651, 2019 | 23 | 2019 |
Development of a single-stranded DNA-binding protein fluorescent fusion toolbox K Dubiel, C Henry, LM Spenkelink, AG Kozlov, EA Wood, S Jergic, ... Nucleic acids research 48 (11), 6053-6067, 2020 | 21 | 2020 |
DnaB helicase dynamics in bacterial DNA replication resolved by single-molecule studies RR Spinks, LM Spenkelink, SA Stratmann, ZQ Xu, NPJ Stamford, ... Nucleic acids research 49 (12), 6804-6816, 2021 | 19 | 2021 |
Design of customizable long linear DNA substrates with controlled end modifications for single-molecule studies SH Mueller, LM Spenkelink, AM van Oijen, JS Lewis Analytical biochemistry 592, 113541, 2020 | 19 | 2020 |
Rapid exchange of stably bound protein and DNA cargo on a DNA origami receptor JWP Brown, RG Alford, JC Walsh, RE Spinney, SY Xu, S Hertel, ... ACS nano 16 (4), 6455-6467, 2022 | 9 | 2022 |
The E. coli helicase does not use ATP during replication LM Spenkelink, RR Spinks, S Jergic, JS Lewis, NE Dixon, AM van Oijen bioRxiv, 2021.07. 07.451541, 2021 | 7 | 2021 |
Single-molecule insights into the dynamics of replicative helicases RR Spinks, LM Spenkelink, NE Dixon, AM Van Oijen Frontiers in Molecular Biosciences 8, 741718, 2021 | 5 | 2021 |
Biology on track: single-molecule visualisation of protein dynamics on linear DNA substrates G Kaur, LM Spenkelink Essays in Biochemistry 65 (1), 5-16, 2021 | 5 | 2021 |
Understanding G-Quadruplex Biology and Stability Using Single-Molecule Techniques N Kusi-Appauh, SF Ralph, AM van Oijen, LM Spenkelink The Journal of Physical Chemistry B 127 (25), 5521-5540, 2023 | 4 | 2023 |
Rapid single-molecule characterisation of enzymes involved in nucleic-acid metabolism SH Mueller, LJ Fitschen, A Shirbini, SM Hamdan, LM Spenkelink, ... Nucleic acids research 51 (1), e5-e5, 2023 | 4 | 2023 |
Production of long linear DNA substrates with site-specific chemical lesions for single-molecule replisome studies G Kaur, LM Spenkelink, JS Lewis, S Jergic, NE Dixon, AM van Oijen Methods in enzymology 672, 299-315, 2022 | 4 | 2022 |
Single-molecule fluorescence methods to study protein exchange kinetics in supramolecular complexes RR Spinks, LM Spenkelink, AM van Oijen Single Stranded DNA Binding Proteins, 49-65, 2021 | 4 | 2021 |