S-nitrosylation and permeation through connexin 43 hemichannels in astrocytes: induction by oxidant stress and reversal by reducing agents MA Retamal, CJ Cortés, L Reuss, MVL Bennett, JC Sáez Proceedings of the National Academy of Sciences 103 (12), 4475-4480, 2006 | 343 | 2006 |
Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA CJ Cortes, HC Miranda, H Frankowski, Y Batlevi, JE Young, A Le, ... Nature neuroscience 17 (9), 1180-1189, 2014 | 180 | 2014 |
Muscle expression of mutant androgen receptor accounts for systemic and motor neuron disease phenotypes in spinal and bulbar muscular atrophy CJ Cortes, SC Ling, LT Guo, G Hung, T Tsunemi, L Ly, S Tokunaga, ... Neuron 82 (2), 295-307, 2014 | 166 | 2014 |
Peripheral androgen receptor gene suppression rescues disease in mouse models of spinal and bulbar muscular atrophy AP Lieberman, Z Yu, S Murray, R Peralta, A Low, S Guo, XX Yu, ... Cell reports 7 (3), 774-784, 2014 | 163 | 2014 |
TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: molecular mechanisms, cellular processes, and emerging therapeutic opportunities CJ Cortes, AR La Spada Neurobiology of disease 122, 83-93, 2019 | 152 | 2019 |
The many faces of autophagy dysfunction in Huntington's disease: from mechanism to therapy CJ Cortes, AR La Spada Drug discovery today 19 (7), 963-971, 2014 | 147 | 2014 |
Rapamycin delays disease onset and prevents PrP plaque deposition in a mouse model of Gerstmann–Sträussler–Scheinker disease CJ Cortes, K Qin, J Cook, A Solanki, JA Mastrianni Journal of Neuroscience 32 (36), 12396-12405, 2012 | 124 | 2012 |
Transcriptional regulation of core autophagy and lysosomal genes by the androgen receptor promotes prostate cancer progression AM Blessing, K Rajapakshe, L Reddy Bollu, Y Shi, MA White, AH Pham, ... Autophagy 13 (3), 506-521, 2017 | 110 | 2017 |
Autophagy in polyglutamine disease: Imposing order on disorder or contributing to the chaos? CJ Cortes, AR La Spada Molecular and Cellular Neuroscience 66, 53-61, 2015 | 59 | 2015 |
Challenges in IBD research: preclinical human IBD mechanisms TT Pizarro, TS Stappenbeck, F Rieder, MJ Rosen, JF Colombel, ... Inflammatory bowel diseases 25 (Supplement_2), S5-S12, 2019 | 54 | 2019 |
Proacrosin/acrosin quantification as an indicator of acrosomal integrity in fresh and frozen dog spermatozoa CJ Cortes, VA Codelia, I Manosalva, J de Lange, M De los Reyes, ... Animal reproduction science 93 (1-2), 165-175, 2006 | 39 | 2006 |
Low-cost gait analysis for behavioral phenotyping of mouse models of neuromuscular disease V Wertman, A Gromova, AR La Spada, CJ Cortes JoVE (Journal of Visualized Experiments), e59878, 2019 | 37 | 2019 |
A novel PRNP-P105S mutation associated with atypical prion disease and a rare PrPSc conformation E Tunnell, R Wollman, S Mallik, CJ Cortes, SJ Dearmond, JA Mastrianni Neurology 71 (18), 1431-1438, 2008 | 32 | 2008 |
Efecto de la refrigeración sobre la motilidad, integridad de membrana acrosomal y reacción acrosomal en espermatozoides caninos P Manosalva, C Cortés, V Leyva, C Valdivia, S De los Reyes, R Barros, ... Revista de Investigaciones Veterinarias del Perú 16 (2), 114-128, 2005 | 28 | 2005 |
Early delivery of misfolded PrP from ER to lysosomes by autophagy CJ Cortes, K Qin, EM Norstrom, WN Green, VP Bindokas, JA Mastrianni International journal of cell biology 2013, 2013 | 24 | 2013 |
Inhibition of the vacuolar H (+)-pump with bafilomycin A1 does not induce acrosome reaction or activate proacrosin in mouse spermatozoa VA Codelia, CJ Cortes, RD Moreno Biochemical and biophysical research communications 337 (4), 1337-1344, 2005 | 23 | 2005 |
X-linked spinal and bulbar muscular atrophy: from clinical genetic features and molecular pathology to mechanisms underlying disease toxicity CJ Cortes, AR La Spada Polyglutamine Disorders, 103-133, 2018 | 21 | 2018 |
Nemo-like kinase is a novel regulator of spinal and bulbar muscular atrophy TW Todd, H Kokubu, HC Miranda, CJ Cortes, AR La Spada, J Lim Elife 4, e08493, 2015 | 15 | 2015 |
Motor neuron degeneration in spinal and Bulbar Muscular Atrophy is a skeletal muscle-driven process: Relevance to therapy development and implications for related motor neuron … CJ Cortes, AR La Spada Rare Diseases 2 (1), e962402, 2014 | 6 | 2014 |
Cross-reactivity of monoclonal antibodies against human acrosin to dog spermatozoa RD Moreno, CJ Cortes, VA Codelia, M De los Reyes REPRODUCTION IN DOMESTIC ANIMALS 41 (4), 317-317, 2006 | 1 | 2006 |