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Lefkothea Papadopoulou
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Fatal infantile cardioencephalomyopathy with COX deficiency and mutations in SCO2, a COX assembly gene
LC Papadopoulou, CM Sue, MM Davidson, K Tanji, I Nishino, JE Sadlock, ...
Nature genetics 23 (3), 333-337, 1999
6781999
CAR T-cell therapy: a new era in cancer immunotherapy
AN Miliotou, LC Papadopoulou
Current pharmaceutical biotechnology 19 (1), 5-18, 2018
5042018
Heme as key regulator of major mammalian cellular functions: molecular, cellular, and pharmacological aspects
AS Tsiftsoglou, AI Tsamadou, LC Papadopoulou
Pharmacology & therapeutics 111 (2), 327-345, 2006
3482006
Differential features of patients with mutations in two COX assembly genes, SURF‐1 and SCO2
CM Sue, C Karadimas, N Checcarelli, K Tanji, LC Papadopoulou, ...
Annals of neurology 47 (5), 589-595, 2000
1532000
The fate of human sperm-derived mtDNA in somatic cells
G Manfredi, D Thyagarajan, LC Papadopoulou, F Pallotti, EA Schon
The American Journal of Human Genetics 61 (4), 953-960, 1997
1351997
Structural and functional impairment of mitochondria in adriamycin-induced cardiomyopathy in mice: suppression of cytochrome c oxidase II gene expression
LC Papadopoulou, G Theophilidis, GN Thomopoulos, AS Tsiftsoglou
Biochemical pharmacology 57 (5), 481-489, 1999
1171999
Effects of hemin on apoptosis, suppression of cytochrome c oxidase gene expression, and bone-marrow toxicity induced by doxorubicin (adriamycin)
LC Papadopoulou, AS Tsiftsoglou
Biochemical pharmacology 52 (5), 713-722, 1996
531996
Mitochondrial Cytochrome c Oxidase as a Target Site for Daunomycin in K-562 Cells and Heart Tissue
LC Papadopoulou, AS Tsiftsoglou
Cancer research 53 (5), 1072-1078, 1993
451993
Synthesis, characterization and biological evaluation of 99mTc/Re–tricarbonyl quinolone complexes
TE Kydonaki, E Tsoukas, F Mendes, AG Hatzidimitriou, A Paulo, ...
Journal of Inorganic Biochemistry 160, 94-105, 2016
402016
Human recombinant mutated forms of the mitochondrial COX assembly Sco2 protein differ from wild-type in physical state and copper binding capacity
PF Foltopoulou, GA Zachariadis, AS Politou, AS Tsiftsoglou, ...
Molecular genetics and metabolism 81 (3), 225-236, 2004
342004
Intracellular delivery of full length recombinant human mitochondrial L-Sco2 protein into the mitochondria of permanent cell lines and SCO2 deficient patient's primary cells
PF Foltopoulou, AS Tsiftsoglou, ID Bonovolias, AT Ingendoh, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1802 (6), 497-508, 2010
292010
In vitro-transcribed (IVT)-mRNA CAR therapy development
AN Miliotou, LC Papadopoulou
Chimeric Antigen Receptor T Cells: Development and Production, 87-117, 2020
232020
Organometallic rhenium tricarbonyl–enrofloxacin and–levofloxacin complexes: Synthesis, albumin-binding, DNA-interaction and cell viability studies
CC Pagoni, VS Xylouri, GC Kaiafas, M Lazou, G Bompola, E Tsoukas, ...
JBIC Journal of Biological Inorganic Chemistry 24, 609-619, 2019
222019
Tackling pharmacological response heterogeneity by PBPK modeling to advance precision medicine productivity of nanotechnology and genomics therapeutics
IS Vizirianakis, AN Miliotou, GA Mystridis, EG Andriotis, II Andreadis, ...
Expert Review of Precision Medicine and Drug Development 4 (3), 139-151, 2019
212019
Transduction of human recombinant proteins into mitochondria as a protein therapeutic approach for mitochondrial disorders
LC Papadopoulou, AS Tsiftsoglou
Pharmaceutical research 28, 2639-2656, 2011
212011
The potential role of cell penetrating peptides in the intracellular delivery of proteins for therapy of erythroid related disorders
LC Papadopoulou, AS Tsiftsoglou
Pharmaceuticals 6 (1), 32-53, 2013
192013
Development of a novel PTD-mediated IVT-mRNA delivery platform for potential protein replacement therapy of metabolic/genetic disorders
AN Miliotou, IS Pappas, G Spyroulias, E Vlachaki, AS Tsiftsoglou, ...
Molecular Therapy-Nucleic Acids 26, 694-710, 2021
182021
Differences in nuclear gene expression between cells containing monomer and dimer mitochondrial genomes
KM Clark, TA Brown, MM Davidson, LC Papadopoulou, DA Clayton
Gene 286 (1), 91-104, 2002
142002
In vivo biodistribution study of TAT-L-Sco2 fusion protein, developed as protein therapeutic for mitochondrial disorders attributed to SCO2 mutations
GC Kaiafas, D Papagiannopoulou, ΑN Miliotou, AS Tsingotjidou, ...
Molecular Genetics and Metabolism Reports 25, 100683, 2020
112020
Production and Transduction of a Human Recombinant β-Globin Chain into Proerythroid K-562 Cells To Replace Missing Endogenous β-Globin
LC Papadopoulou, A Ingendoh-Tsakmakidis, CN Mpoutoureli, ...
Molecular Pharmaceutics 15 (12), 5665-5677, 2018
82018
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